verapamil has been researched along with Benign Neoplasms, Brain in 15 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As a novel type of nano-radiosensitizer, silver nanoparticles (AgNPs) have shown promising radiosensitizing properties in the radiotherapy of glioma, but their ability to efficiently enter and accumulate in tumor cells needs to be improved." | 8.02 | Increasing the accumulation of aptamer AS1411 and verapamil conjugated silver nanoparticles in tumor cells to enhance the radiosensitivity of glioma. ( Cao, Y; Chen, W; Li, D; Liu, P; Ma, J; Yang, H; Zhao, J, 2021) |
| " As a novel type of nano-radiosensitizer, silver nanoparticles (AgNPs) have shown promising radiosensitizing properties in the radiotherapy of glioma, but their ability to efficiently enter and accumulate in tumor cells needs to be improved." | 4.02 | Increasing the accumulation of aptamer AS1411 and verapamil conjugated silver nanoparticles in tumor cells to enhance the radiosensitivity of glioma. ( Cao, Y; Chen, W; Li, D; Liu, P; Ma, J; Yang, H; Zhao, J, 2021) |
| "Membrane-modifying agents such as reserpine, calcium antagonists (nicardipine, verapamil) and calmodulin inhibitor (trifluoperazine) were found to enhance the cytotoxicity of ACNU in vitro and in vivo in ACNU-resistant C 6 (C 6/ACNU) glioma." | 3.67 | [Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma]. ( Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, J | 1 |
| Li, D | 1 |
| Ma, J | 1 |
| Yang, H | 1 |
| Chen, W | 1 |
| Cao, Y | 1 |
| Liu, P | 1 |
| Hanif, F | 1 |
| Perveen, K | 1 |
| Malhi, SM | 1 |
| Jawed, H | 1 |
| Simjee, SU | 1 |
| Zanotti-Fregonara, P | 1 |
| Veronese, M | 1 |
| Pascual, B | 1 |
| Rostomily, RC | 1 |
| Turkheimer, F | 1 |
| Masdeu, JC | 1 |
| Mrozikiewicz, PM | 1 |
| Bogacz, A | 1 |
| Bartkowiak-Wieczorek, J | 1 |
| Kujawski, R | 1 |
| Mikolajczak, PL | 1 |
| Ozarowski, M | 1 |
| Czerny, B | 1 |
| Mrozikiewicz-Rakowska, B | 1 |
| Grzeskowiak, E | 1 |
| Bedford, RF | 1 |
| Dacey, R | 1 |
| Winn, HR | 1 |
| Lynch, C | 1 |
| Matsukado, K | 1 |
| Ikezaki, K | 1 |
| Nomura, T | 1 |
| Fukui, M | 1 |
| Ducharme, J | 1 |
| Abdullah, S | 1 |
| Wainer, IW | 1 |
| Straub, H | 1 |
| Köhling, R | 1 |
| Lüke, A | 1 |
| Fauteck, JD | 1 |
| Speckmann, EJ | 1 |
| Moskopp, D | 1 |
| Wassmann, H | 1 |
| Tuxhorn, I | 1 |
| Wolf, P | 1 |
| Pannek, H | 1 |
| Oppel, F | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Rieger, L | 1 |
| Rieger, J | 1 |
| Winter, S | 1 |
| Streffer, J | 1 |
| Esser, P | 1 |
| Dichgans, J | 1 |
| Meyermann, R | 1 |
| Weller, M | 1 |
| Andersson, U | 1 |
| Grankvist, K | 1 |
| Bergenheim, AT | 1 |
| Behnam-Motlagh, P | 1 |
| Hedman, H | 1 |
| Henriksson, R | 1 |
| Bowles, AP | 1 |
| Pantazis, CG | 1 |
| Wansley, W | 1 |
| Yoshida, T | 2 |
| Shimizu, K | 2 |
| Ushio, Y | 2 |
| Hayakawa, T | 1 |
| Kato, A | 1 |
| Mogami, H | 2 |
| Sakamoto, Y | 2 |
| Kaba, K | 1 |
| Tani, E | 1 |
| Morimura, T | 1 |
| Matsumoto, T | 1 |
1 trial available for verapamil and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity.
Topics: Adult; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Brain Neoplasms; Chromatogr | 1996 |
14 other studies available for verapamil and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Increasing the accumulation of aptamer AS1411 and verapamil conjugated silver nanoparticles in tumor cells to enhance the radiosensitivity of glioma.
Topics: Aptamers, Nucleotide; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Metal Nanoparticles; Oligod | 2021 |
Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S | 2018 |
The validity of
Topics: Animals; Biomarkers; Biopsy; Blood-Brain Barrier; Brain; Brain Neoplasms; Carbazoles; Fluorine Radio | 2019 |
Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Neoplasms; Ginkgo biloba; Hypericum | 2014 |
Adverse impact of a calcium entry-blocker (verapamil) on intracranial pressure in patients with brain tumors.
Topics: Brain Neoplasms; Humans; Intracranial Pressure; Verapamil | 1983 |
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Cir | 1996 |
The effects of verapamil and flunarizine on epileptiform activity induced by bicuculline and low Mg2+ in neocortical tissue of epileptic and primary non-epileptic patients.
Topics: Astrocytoma; Bicuculline; Brain Neoplasms; Cerebral Cortex; Ependymoma; Epilepsy, Frontal Lobe; Epil | 1996 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, | 2000 |
Rapid induction of long-lasting drug efflux activity in brain vascular endothelial cells but not malignant glioma following irradiation.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2002 |
Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Drug Screening Assays, Antitumor; Fluorescent D | 1990 |
[Mechanism and overcoming of resistance in ACNU-resistant sublines of rat brain tumors].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Membrane Permeability; Drug Resistance; Glioma | 1986 |
[Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Drug T | 1986 |
Potentiation of vincristine effect in human and murine gliomas by calcium channel blockers or calmodulin inhibitors.
Topics: Animals; Brain Neoplasms; Calcium Channel Blockers; Calmodulin; Drug Synergism; Glioma; Humans; In V | 1985 |