Page last updated: 2024-10-24

verapamil and Aura

verapamil has been researched along with Aura in 44 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"Faster metabolism of (R)-[(11)C]verapamil in epilepsy patients may be caused by hepatic cytochrome P450 enzyme induction by antiepileptic drugs."9.13Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients. ( Abrahim, A; Bauer, M; Baumgartner, C; Joukhadar, C; Karch, R; Kletter, K; Lammertsma, AA; Langer, O; Lubberink, M; Luurtsema, G; Müller, M; Pataraia, E, 2008)
"Verapamil, a voltage-gated calcium channel blocker, has been occasionally reported to have some effect on reducing seizure frequency in drug-resistant epilepsy or status epilepticus."7.80Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: a pilot study. ( Iannetti, P; Nicita, F; Nikanorova, M; Papetti, L; Parisi, P; Spalice, A, 2014)
" Pentylenetetrazole (PTZ)-kindled and spontaneous model of epilepsy (EL) mice were used as models of chemically induced and spontaneous epilepsy, respectively."7.80Pharmacoproteomics-based reconstruction of in vivo P-glycoprotein function at blood-brain barrier and brain distribution of substrate verapamil in pentylenetetrazole-kindled epilepsy, spontaneous epilepsy, and phenytoin treatment models. ( Ohtsuki, S; Terasaki, T; Uchida, Y, 2014)
"The failure of the maximum tolerated dosage to improve seizure control in dogs with phenobarbital-resistant epilepsy argues against the suitability of verapamil add-on treatment to overcome pharmacoresistance."7.77Add-on treatment with verapamil in pharmacoresistant canine epilepsy. ( Jambroszyk, M; Potschka, H; Tipold, A, 2011)
"Verapamil was added to the antiepileptic drug regimen of a 24-year-old woman with intractable epilepsy."7.72Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy. ( McAuley, JW; Moore, JL; Summers, MA, 2004)
"This was a single-centered, randomized, double-blind and placebo-controlled trial evaluating verapamil as an add-on therapy for adult patients with refractory epilepsy."5.19A pilot double-blind trial using verapamil as adjuvant therapy for refractory seizures. ( Ali, A; Andrade, DM; Borlot, F; Verocai, F; Wither, RG; Wu, N, 2014)
"Faster metabolism of (R)-[(11)C]verapamil in epilepsy patients may be caused by hepatic cytochrome P450 enzyme induction by antiepileptic drugs."5.13Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients. ( Abrahim, A; Bauer, M; Baumgartner, C; Joukhadar, C; Karch, R; Kletter, K; Lammertsma, AA; Langer, O; Lubberink, M; Luurtsema, G; Müller, M; Pataraia, E, 2008)
"Literature searches were conducted utilizing PubMed and MEDLINE databases employing combinations of search terms including, but not limited to, "epilepsy", "refractory", "seizure", and the following medications: acetazolamide, amantadine, bumetanide, imipramine, lidocaine, verapamil, and various stimulants."4.95Outside the box: Medications worth considering when traditional antiepileptic drugs have failed. ( Perry, MS; Turner, AL, 2017)
"Verapamil, a voltage-gated calcium channel blocker, has been occasionally reported to have some effect on reducing seizure frequency in drug-resistant epilepsy or status epilepticus."3.80Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: a pilot study. ( Iannetti, P; Nicita, F; Nikanorova, M; Papetti, L; Parisi, P; Spalice, A, 2014)
" Pentylenetetrazole (PTZ)-kindled and spontaneous model of epilepsy (EL) mice were used as models of chemically induced and spontaneous epilepsy, respectively."3.80Pharmacoproteomics-based reconstruction of in vivo P-glycoprotein function at blood-brain barrier and brain distribution of substrate verapamil in pentylenetetrazole-kindled epilepsy, spontaneous epilepsy, and phenytoin treatment models. ( Ohtsuki, S; Terasaki, T; Uchida, Y, 2014)
"The failure of the maximum tolerated dosage to improve seizure control in dogs with phenobarbital-resistant epilepsy argues against the suitability of verapamil add-on treatment to overcome pharmacoresistance."3.77Add-on treatment with verapamil in pharmacoresistant canine epilepsy. ( Jambroszyk, M; Potschka, H; Tipold, A, 2011)
"Verapamil was added to the antiepileptic drug regimen of a 24-year-old woman with intractable epilepsy."3.72Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy. ( McAuley, JW; Moore, JL; Summers, MA, 2004)
"In order to determine whether the anticonvulsant effect of 2, 3-benzodiazepines is also displayed in a model of in vitro epilepsy, such as the "epileptiform" hippocampal slice, we studied the effects of 2,3-benzodiazepine 1-(4-aminophenyl)-4-methyl-7, 8-methylenedioxe-5H 2,3-benzodiazepine hydrochloride (GYKI 52466) and some new 2,3-benzodiazepine derivatives on CA1 basal neuronal excitability and on CA1 epileptiform burst activity produced by 4-aminopyridine in rat hippocampal slices."3.70Effects of GYKI 52466 and some 2,3-benzodiazepine derivatives on hippocampal in vitro basal neuronal excitability and 4-aminopyridine epileptic activity. ( Gatta, F; Marinelli, S; Sagratella, S, 2000)
" The paper addresses this question by exploring the antiepileptic efficacy of the L-type calcium channel blockers verapamil and nifedipine in low-Mg(2+)-epilepsy in rat hippocampal slices of different postnatal (PN) ages."3.70Differential involvement of L-type calcium channels in epileptogenesis of rat hippocampal slices during ontogenesis. ( Köhling, R; Speckmann, EJ; Straub, H, 2000)
"The aim of the present study was to test whether the organic calcium channel blocker verapamil acts not only on spontaneously occurring epileptiform field potentials (EFP) but also on EFP triggered by single electrical stimuli in the low-Mg2+ epilepsy model."3.69Spontaneous and stimulus-triggered epileptic discharges: delayed antiepileptic effect with triggering. ( Köhling, R; Speckmann, EJ; Straub, H, 1994)
"Carbamazepine (CBZ) is known to have beneficial effects in the treatment of epilepsies and in the prophylaxis of affective disorders."3.68Calcium-antagonistic effects of carbamazepine in epilepsies and affective psychoses. ( Bingmann, D; Düsing, R; Grunze, H; Liu, Z; Mayer, A; Schirrmacher, K; Walden, J, 1993)
"Carbamazepine (CBZ) is used in neurology for the treatment of epilepsies and trigeminal neuralgia and in psychiatry for the prophylactic treatment of affective and schizoaffective psychoses."3.68Calcium antagonistic effects of carbamazepine as a mechanism of action in neuropsychiatric disorders: studies in calcium dependent model epilepsies. ( Bingmann, D; Düsing, R; Grunze, H; Liu, Z; Walden, J, 1992)
"Trimipramine has been classified as an atypical tricyclic antidepressant, because only weak inhibitory effects on serotonin and/or noradrenaline reuptake have been found."1.30Effects of the atypical antidepressant trimipramine on field potentials in the low Mg2+-model in guinea pig hippocampal slices. ( Berger, M; Langosch, JM; Repp, M; Walden, J, 1998)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.82)18.7374
1990's18 (40.91)18.2507
2000's11 (25.00)29.6817
2010's12 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anger, T1
Madge, DJ1
Mulla, M1
Riddall, D1
Bai, YF1
Chiu, M1
Chan, ES1
Axerio-Cilies, P1
Lu, J1
Huh, L1
Connolly, MB1
Guella, I1
Farrer, MJ1
Xu, ZD1
Liu, L1
Demos, M1
Wang, YT1
Turner, AL1
Perry, MS1
Nicita, F1
Spalice, A1
Papetti, L1
Nikanorova, M1
Iannetti, P1
Parisi, P1
Ma, A1
Wang, C1
Chen, Y1
Yuan, W1
Kumar, A1
Tripathi, D1
Paliwal, VK1
Neyaz, Z1
Agarwal, V1
Uchida, Y1
Ohtsuki, S1
Terasaki, T1
Borlot, F1
Wither, RG1
Ali, A1
Wu, N1
Verocai, F1
Andrade, DM1
Han, DY1
Guan, BJ1
Wang, YJ1
Hatzoglou, M1
Mu, TW1
Bauer, M2
Karch, R2
Neumann, F1
Wagner, CC1
Kletter, K2
Müller, M2
Löscher, W2
Zeitlinger, M1
Langer, O2
Jambroszyk, M1
Tipold, A1
Potschka, H2
Kovács, R1
Raue, C1
Gabriel, S1
Heinemann, U1
Chen, L1
Feng, P1
Li, Y1
Zhou, D1
Fedrowitz, M1
Gorji, A2
Moddel, G1
Speckmann, EJ11
Summers, MA1
Moore, JL1
McAuley, JW1
Rüschenschmidt, C1
Straub, H8
Köhling, R6
Siep, E1
Doyle, KM1
Kirby, BP1
Murphy, D1
Shaw, GG1
Abrahim, A1
Luurtsema, G1
Lubberink, M1
Pataraia, E1
Joukhadar, C1
Lammertsma, AA1
Baumgartner, C1
Link, MC1
Wiemann, M2
Bingmann, D3
Kryzhanovskiĭ, GN1
Karpova, MN1
Abrosimov, IIu1
Pankov, OIu1
Lakinina, MV1
Stanimirovic, DB1
Bacic, F1
Uematsu, S1
Spatz, M1
Walden, J5
Grunze, H2
Mayer, A1
Düsing, R2
Schirrmacher, K1
Liu, Z2
Lehmenkükhler, A1
Nicholson, C1
Jones, D1
Altrup, U1
Abellán, I1
Sempere, AP1
Langosch, JM1
Repp, M1
Berger, M1
Marinelli, S1
Gatta, F1
Sagratella, S3
Owen, A1
Pirmohamed, M1
Tettey, JN1
Morgan, P1
Chadwick, D1
Park, BK1
Chen, Q1
Xie, Y1
Chai, H1
Sasa, M1
Ishihara, K1
Momiyama, T1
Renming, X1
Todo, N1
Amano, T1
Serikawa, T1
Yamada, J1
Pohl, M1
Popoli, P1
Pezzola, A1
Zeng, YC1
Scotti de Carolis, A2
Woodcock, BG1
Kirsten, R1
Nelson, K1
Rietbrock, S1
Hopf, R1
Kaltenbach, M1
Aicardi, G1
Schwartzkroin, PA1
Witte, OW1
Frank, C1
Benedetti, M1
Marrosu, F1
Mereu, G1
Fratta, W1
Carcangiu, P1
Camarri, F1
Gessa, GL1

Reviews

3 reviews available for verapamil and Aura

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo

2001
Outside the box: Medications worth considering when traditional antiepileptic drugs have failed.
    Seizure, 2017, Volume: 50

    Topics: Amantadine; Anticonvulsants; Bumetanide; Central Nervous System Stimulants; Epilepsy; Humans; Imipra

2017
Epileptogenesis: contributions of calcium ions and antiepileptic calcium antagonists.
    Acta neurologica Scandinavica. Supplementum, 1992, Volume: 140

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroencephalography; Epilep

1992

Trials

2 trials available for verapamil and Aura

ArticleYear
A pilot double-blind trial using verapamil as adjuvant therapy for refractory seizures.
    Epilepsy research, 2014, Volume: 108, Issue:9

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anticonvulsants; Calcium Channel Blockers; Combined M

2014
Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:1

    Topics: Adult; Calcium Channel Blockers; Carbon Radioisotopes; Case-Control Studies; Chromatography, High Pr

2008

Other Studies

39 other studies available for verapamil and Aura

ArticleYear
Pathophysiology of and therapeutic options for a GABRA1 variant linked to epileptic encephalopathy.
    Molecular brain, 2019, 11-10, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Child; Chloride Channels; Diazepam; Electroencephalography; Epilepsy; Female; G

2019
Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: a pilot study.
    Seizure, 2014, Volume: 23, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Ep

2014
P-glycoprotein alters blood-brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barri

2013
Role of P-glycoprotein in refractoriness of seizures to antiepileptic drugs in Lennox-Gastaut syndrome.
    Journal of child neurology, 2015, Volume: 30, Issue:2

    Topics: Adolescent; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channe

2015
Pharmacoproteomics-based reconstruction of in vivo P-glycoprotein function at blood-brain barrier and brain distribution of substrate verapamil in pentylenetetrazole-kindled epilepsy, spontaneous epilepsy, and phenytoin treatment models.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:10

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barri

2014
L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABA(A) Receptors.
    ACS chemical biology, 2015, Sep-18, Volume: 10, Issue:9

    Topics: Calcium Channel Blockers; Calcium Channels, L-Type; Calnexin; Calreticulin; Cell Line; Endoplasmic R

2015
Assessment of regional differences in tariquidar-induced P-glycoprotein modulation at the human blood-brain barrier.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:3

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Calcium

2010
Add-on treatment with verapamil in pharmacoresistant canine epilepsy.
    Epilepsia, 2011, Volume: 52, Issue:2

    Topics: Age of Onset; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blo

2011
Functional test of multidrug transporter activity in hippocampal-neocortical brain slices from epileptic patients.
    Journal of neuroscience methods, 2011, Sep-15, Volume: 200, Issue:2

    Topics: Adjuvants, Pharmaceutic; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; E

2011
Influences of "spasmolytic powder" on pgp expression of Coriaria Lactone-kindling drug-resistant epileptic rat model.
    Journal of molecular neuroscience : MN, 2013, Volume: 51, Issue:1

    Topics: Animals; Anticonvulsants; Arthropods; ATP Binding Cassette Transporter, Subfamily B, Member 1; Disea

2013
P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats.
    Neuroscience letters, 2002, Jul-26, Volume: 327, Issue:3

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barri

2002
Background potassium concentrations and epileptiform discharges. II. Involvement of calcium channels.
    Brain research, 2003, Jan-03, Volume: 959, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Epilepsy; Extracellular Space; Female;

2003
Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:10

    Topics: Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance; Dr

2004
Reduction of human neocortical and guinea pig CA1-neuron A-type currents by organic calcium channel blockers.
    Neuroscience letters, 2004, Sep-16, Volume: 368, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Animals; Calcium Channel Blockers; Child; Epilepsy; Fem

2004
Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo.
    Neuroscience letters, 2005, Jun-03, Volume: 380, Issue:3

    Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System; Convuls

2005
Organic and inorganic calcium antagonists inhibit veratridine-induced epileptiform activity in CA3 neurons of the guinea pig.
    Epilepsy research, 2008, Volume: 78, Issue:2-3

    Topics: Animals; Calcium; Calcium Channel Blockers; Cobalt; Convulsants; Epilepsy; Guinea Pigs; Hippocampus;

2008
Spontaneous and stimulus-triggered epileptic discharges: delayed antiepileptic effect with triggering.
    Experimental brain research, 1994, Volume: 100, Issue:3

    Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Guinea

1994
Picrotoxin-induced epileptic activity in hippocampal and neocortical slices (guinea pig): suppression by organic calcium channel blockers.
    Brain research, 1994, Sep-26, Volume: 658, Issue:1-2

    Topics: Animals; Cerebral Cortex; Depression, Chemical; Epilepsy; Female; Flunarizine; Guinea Pigs; Hippocam

1994
[Anticonvulsant activity of sodium valproate and various calcium antagonists during their combined use in mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:3

    Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combi

1993
Profile of prostaglandins induced by endothelin-1 in human brain capillary endothelium.
    Neurochemistry international, 1993, Volume: 23, Issue:4

    Topics: Analysis of Variance; Capillaries; Cell Line; Dexamethasone; Endothelin Receptor Antagonists; Endoth

1993
Calcium-antagonistic effects of carbamazepine in epilepsies and affective psychoses.
    Neuropsychobiology, 1993, Volume: 27, Issue:3

    Topics: Animals; Caffeine; Calcium Channel Blockers; Carbamazepine; Epilepsy; Guinea Pigs; Hippocampus; In V

1993
Superfusion of verapamil on the cerebral cortex does not suppress epileptic discharges due to restricted diffusion (rats, in vivo).
    Brain research, 1993, Oct-29, Volume: 626, Issue:1-2

    Topics: Animals; Cerebral Cortex; Diffusion; Epilepsy; Perfusion; Rats; Verapamil

1993
Simultaneous blockade of intracellular calcium increases and of neuronal epileptiform depolarizations by verapamil.
    Brain research, 1996, Sep-23, Volume: 734, Issue:1-2

    Topics: Animals; Calcium; Calcium Channel Blockers; Electrophysiology; Epilepsy; Helix, Snails; Intracellula

1996
[The Valencia Neurological Society. A 45-year-old man with epileptic crises].
    Revista de neurologia, 1997, Volume: 25, Issue:144

    Topics: Anticonvulsants; Epilepsy; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Spain; Verapamil

1997
Strychnine-induced epileptiform activity in hippocampal and neocortical slice preparations: suppression by the organic calcium antagonists verapamil and flunarizine.
    Brain research, 1997, Oct-31, Volume: 773, Issue:1-2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Epilepsy; Evoked Pote

1997
Effects of the atypical antidepressant trimipramine on field potentials in the low Mg2+-model in guinea pig hippocampal slices.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1998, Volume: 8, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Antidepressive Agents, Tricyclic; Calcium C

1998
Effects of GYKI 52466 and some 2,3-benzodiazepine derivatives on hippocampal in vitro basal neuronal excitability and 4-aminopyridine epileptic activity.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: 4-Aminopyridine; Animals; Anti-Anxiety Agents; Anticonvulsants; Axons; Benzodiazepines; Calcium Chan

2000
Differential involvement of L-type calcium channels in epileptogenesis of rat hippocampal slices during ontogenesis.
    Neurobiology of disease, 2000, Volume: 7, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels, L-Type; Epilepsy

2000
Carbamazepine is not a substrate for P-glycoprotein.
    British journal of clinical pharmacology, 2001, Volume: 51, Issue:4

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cel

2001
[Effects of calcium channel blocker verapamil on hippocampal kindled seizures induced by coriaria lactone in rabbits].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1992, Volume: 23, Issue:3

    Topics: Animals; Electroencephalography; Epilepsy; Female; Hippocampus; Injections, Intraventricular; Kindli

1992
Abnormal calcium current in hippocampal CA3 pyramidal cells of the spontaneously epileptic rat (SER).
    The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:2

    Topics: Action Potentials; Animals; Calcium Channels; Electric Stimulation; Epilepsy; Flunarizine; Hippocamp

1992
Calcium antagonistic effects of carbamazepine as a mechanism of action in neuropsychiatric disorders: studies in calcium dependent model epilepsies.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:4

    Topics: Animals; Calcium Channel Blockers; Carbamazepine; Epilepsy; Extracellular Space; Guinea Pigs; Hippoc

1992
Low magnesium-induced epileptiform discharges in guinea pig hippocampal slices: depression by the organic calcium antagonist verapamil.
    Brain research, 1992, Apr-10, Volume: 577, Issue:1

    Topics: Animals; Anticonvulsants; Epilepsy; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques

1992
Cromakalim (BRL 34915) counteracts the epileptiform activity elicited by diltiazem and verapamil in rats.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Animals; Anticonvulsants; Benzopyrans; Cromakalim; Diltiazem; Electric Stimulation; Electroencephalo

1991
A reduction in verapamil concentrations with phenytoin.
    The New England journal of medicine, 1991, Oct-17, Volume: 325, Issue:16

    Topics: Adult; Cardiomyopathy, Hypertrophic; Drug Interactions; Epilepsy; Female; Humans; Phenytoin; Verapam

1991
Suppression of epileptiform burst discharges in CA3 neurons of rat hippocampal slices by the organic calcium channel blocker, verapamil.
    Experimental brain research, 1990, Volume: 81, Issue:2

    Topics: Action Potentials; Animals; Calcium Channels; Electric Stimulation; Epilepsy; Female; Hippocampus; I

1990
Suppression of focal epileptiform discharges by intraventricular perfusion of a calcium antagonist.
    Electroencephalography and clinical neurophysiology, 1985, Volume: 61, Issue:4

    Topics: Animals; Brain; Calcium Channel Blockers; Cerebral Ventricles; Electroencephalography; Epilepsy; Pen

1985
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices.
    Brain research, 1988, Feb-16, Volume: 441, Issue:1-2

    Topics: Adenosine; Animals; Caffeine; Calcium; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male;

1988
Different epileptogenic activities of murine and ovine corticotropin-releasing factor.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: Animals; Corticotropin-Releasing Hormone; Electroencephalography; Epilepsy; Injections, Intraventric

1987