verapamil and Ataxia
verapamil has been researched along with Ataxia in 3 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"The possibility that non-sedating antihistamines could elicit sedation in mice due to drug-induced inhibition of brain PgP was evaluated by measuring the ability of desloratadine alone or in combination with verapamil to cause ataxia in mice." | 3.74 | Verapamil, but not probenecid, co-administration can convert desloratadine to a sedating antihistamine in mice. ( Bachmann, K; Bykowski, C; Dhananjeyan, M; Erhardt, P; Hacker, M; Katta, A; White, DB, 2007) |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Katta, A | 1 |
Dhananjeyan, M | 1 |
Bykowski, C | 1 |
Erhardt, P | 1 |
Hacker, M | 1 |
White, DB | 1 |
Bachmann, K | 1 |
Baliño, P | 1 |
Pastor, R | 1 |
Aragon, CM | 1 |
Beattie, B | 1 |
Biller, J | 1 |
Mehlhaus, B | 1 |
Murray, M | 1 |
Other Studies
3 other studies available for verapamil and Ataxia
Article | Year |
---|---|
Verapamil, but not probenecid, co-administration can convert desloratadine to a sedating antihistamine in mice.
Topics: Animals; Ataxia; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Chromatography, Liq | 2007 |
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: effects of diltiazem and verapamil.
Topics: Analysis of Variance; Animals; Ataxia; Behavior, Animal; Caffeine; Calcium Channel Blockers; Calcium | 2010 |
Verapamil-induced carbamazepine neurotoxicity. A report of two cases.
Topics: Adult; Ataxia; Carbamazepine; Drug Interactions; Female; Humans; Middle Aged; Seizures; Verapamil | 1988 |