verapamil has been researched along with Astrocytoma, Grade IV in 9 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The interactions between anticancer drugs such as carmustine (BCNU), vincristine (VCR) and procarbazine (PCB) and calcium channel blockers such as nimodipine and verapamil on cultured cells of glioblastoma from eight patients were therefore tested." | 7.70 | The effects of anticancer drugs in combination with nimodipine and verapamil on cultured cells of glioblastoma multiforme. ( Deliorman, S; Durmaz, R; Erol, K; Işiksoy, S; Tel, E; Uyar, R, 1999) |
| "Using the technique of alkaline filter elution, we have evaluated the DNA damage induced by doxorubicin and etoposide in a rat glioblastoma cell line, C6, and its doxorubicin-selected resistant variant, C6 0." | 7.69 | Differential stabilization of topoisomerase-II-DNA cleavable complexes by doxorubicin and etoposide in doxorubicin-resistant rat glioblastoma cells. ( de Tinguy-Moreaud, E; Denois, F; Lagarde, P; Montaudon, D; Pourquier, P; Robert, J, 1997) |
| " The interactions between anticancer drugs such as carmustine (BCNU), vincristine (VCR) and procarbazine (PCB) and calcium channel blockers such as nimodipine and verapamil on cultured cells of glioblastoma from eight patients were therefore tested." | 3.70 | The effects of anticancer drugs in combination with nimodipine and verapamil on cultured cells of glioblastoma multiforme. ( Deliorman, S; Durmaz, R; Erol, K; Işiksoy, S; Tel, E; Uyar, R, 1999) |
| "Using the technique of alkaline filter elution, we have evaluated the DNA damage induced by doxorubicin and etoposide in a rat glioblastoma cell line, C6, and its doxorubicin-selected resistant variant, C6 0." | 3.69 | Differential stabilization of topoisomerase-II-DNA cleavable complexes by doxorubicin and etoposide in doxorubicin-resistant rat glioblastoma cells. ( de Tinguy-Moreaud, E; Denois, F; Lagarde, P; Montaudon, D; Pourquier, P; Robert, J, 1997) |
| "Glioblastoma multiforme is an aggressive form of human astrocytoma, with poor prognosis due to multi-drug resistance to a number of anticancer drugs." | 1.40 | Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns. ( Habicht, KL; Khadeer, MA; Moaddel, R; Shimmo, R; Singh, NS; Wainer, IW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Yu, J | 1 |
| Pan, H | 1 |
| Hu, P | 1 |
| Hao, Y | 1 |
| Cai, W | 1 |
| Zhu, H | 1 |
| Yu, AD | 1 |
| Xie, X | 1 |
| Ma, D | 1 |
| Yuan, J | 1 |
| Hanif, F | 1 |
| Perveen, K | 1 |
| Malhi, SM | 1 |
| Jawed, H | 1 |
| Simjee, SU | 1 |
| Habicht, KL | 1 |
| Singh, NS | 1 |
| Khadeer, MA | 1 |
| Shimmo, R | 1 |
| Wainer, IW | 1 |
| Moaddel, R | 1 |
| Syatkin, SP | 1 |
| Frolov, VA | 1 |
| Gridina, NY | 1 |
| Draguntseva, NG | 1 |
| Skorik, AS | 1 |
| Kiwit, JC | 1 |
| Hertel, A | 1 |
| Matuschek, AE | 1 |
| Montaudon, D | 1 |
| Pourquier, P | 1 |
| Denois, F | 1 |
| de Tinguy-Moreaud, E | 1 |
| Lagarde, P | 1 |
| Robert, J | 1 |
| Labrakakis, C | 1 |
| Patt, S | 1 |
| Hartmann, J | 1 |
| Kettenmann, H | 1 |
| Durmaz, R | 1 |
| Deliorman, S | 1 |
| Uyar, R | 1 |
| Işiksoy, S | 1 |
| Erol, K | 1 |
| Tel, E | 1 |
| Rieger, L | 1 |
| Rieger, J | 1 |
| Winter, S | 1 |
| Streffer, J | 1 |
| Esser, P | 1 |
| Dichgans, J | 1 |
| Meyermann, R | 1 |
| Weller, M | 1 |
9 other studies available for verapamil and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; G | 2007 |
Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S | 2018 |
Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily | 2014 |
Differential Diagnostics of Neoplastic and Inflammatory Processes in the Brain by Modifications NMDA Receptor Activity in Blood Cells with Verapamil and Ketamine.
Topics: Brain Injuries, Traumatic; Calcium Channel Blockers; Case-Control Studies; Cell Aggregation; Diagnos | 2016 |
Reversal of chemoresistance in malignant gliomas by calcium antagonists: correlation with the expression of multidrug-resistant p-glycoprotein.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Membe | 1994 |
Differential stabilization of topoisomerase-II-DNA cleavable complexes by doxorubicin and etoposide in doxorubicin-resistant rat glioblastoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transp | 1997 |
Functional GABA(A) receptors on human glioma cells.
Topics: Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Flunitrazepam; GABA Agonists; GABA Modulat | 1998 |
The effects of anticancer drugs in combination with nimodipine and verapamil on cultured cells of glioblastoma multiforme.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Bloc | 1999 |
Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, | 2000 |