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verapamil and Asthma, Exercise-Induced

verapamil has been researched along with Asthma, Exercise-Induced in 11 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Asthma, Exercise-Induced: Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).

Research Excerpts

ExcerptRelevanceReference
"Fifteen children with exercise-induced asthma (EIA) participated in a double-blind trial comparing the protective effects of inhaled sodium cromoglycate (20 mg/2 ml), ipratropium bromide (500 micrograms/2 ml) and verapamil (5 mg/2 ml)."9.06Comparison of the effects of inhaled calcium antagonist verapamil, sodium cromoglycate and ipratropium bromide on exercise-induced bronchoconstriction in children with asthma. ( Andreoli, A; Antolini, I; Boner, AL; De Stefano, G; Sette, L, 1987)
"The protective effect of 5 mg/2 ml and 10 mg/4 ml of the calcium antagonist verapamil on methacholine challenge and exercise were evaluated in two groups of asthmatic children."9.06Effects of different dosages of the calcium antagonist verapamil in exercise- and methacholine-induced bronchospasm in children with chronic asthma. ( Boner, AL; De Stefano, G; Sette, L, 1987)
"Twenty-four patients who were known to develop bronchoconstriction in response to isocapnic hyperventilation (IH) took part in a double-blind, placebo-controlled trial to assess the effects of verapamil (5 mg) and sodium cromoglycate (SCG) 20 mg in the prevention of IH-induced bronchoconstriction."9.05Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation. ( Biggs, BA; Fergusson, RJ; Grant, IW; Rafferty, P; Tweeddale, PM, 1985)
"Fifteen children with exercise-induced asthma (EIA) participated in a double-blind trial comparing the protective effects of inhaled sodium cromoglycate (20 mg/2 ml), ipratropium bromide (500 micrograms/2 ml) and verapamil (5 mg/2 ml)."5.06Comparison of the effects of inhaled calcium antagonist verapamil, sodium cromoglycate and ipratropium bromide on exercise-induced bronchoconstriction in children with asthma. ( Andreoli, A; Antolini, I; Boner, AL; De Stefano, G; Sette, L, 1987)
"The protective effect of 5 mg/2 ml and 10 mg/4 ml of the calcium antagonist verapamil on methacholine challenge and exercise were evaluated in two groups of asthmatic children."5.06Effects of different dosages of the calcium antagonist verapamil in exercise- and methacholine-induced bronchospasm in children with chronic asthma. ( Boner, AL; De Stefano, G; Sette, L, 1987)
"Ten patients with exercise-induced asthma participated in a single-blind trial comparing the protective effects of inhaled verapamil (estimated dose 3 mg) and sodium cromoglycate (estimated dose 12 mg)."5.05Calcium antagonists in exercise-induced asthma. ( Patel, KR, 1981)
"Twenty-four patients who were known to develop bronchoconstriction in response to isocapnic hyperventilation (IH) took part in a double-blind, placebo-controlled trial to assess the effects of verapamil (5 mg) and sodium cromoglycate (SCG) 20 mg in the prevention of IH-induced bronchoconstriction."5.05Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation. ( Biggs, BA; Fergusson, RJ; Grant, IW; Rafferty, P; Tweeddale, PM, 1985)
" Certain drugs such as antihistamines and ketotifen may be more effective administered by inhalation since high concentrations with reduced unwanted effects can be achieved on the bronchial surface where, in allergic asthma, the critical initial interaction between sensitized mast cells (mucosal?) and allergen with subsequent mediator release occurs."3.67Use of inhaled calcium channel blocking agents in the treatment of asthma. ( Bennett, J; Davies, RJ; Osman, J, 1984)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Solway, J1
Patel, KR3
König, P1
Davies, RJ1
Bennett, J1
Osman, J1
Kerr, JW1
Ahmed, T1
Abraham, WM1
Berman, BA1
Ross, RN1
Boner, AL2
Antolini, I1
Andreoli, A1
De Stefano, G2
Sette, L2
Rafferty, P1
Fergusson, RJ1
Tweeddale, PM1
Biggs, BA1
Grant, IW1

Reviews

2 reviews available for verapamil and Asthma, Exercise-Induced

ArticleYear
Role of calcium-channel blockers in obstructive airway disease.
    Chest, 1985, Volume: 88, Issue:2 Suppl

    Topics: Acetylcholine; Animals; Asthma; Asthma, Exercise-Induced; Calcium; Calcium Channel Blockers; Diltiaz

1985
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
    Annals of allergy, 1986, Volume: 56, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca

1986

Trials

5 trials available for verapamil and Asthma, Exercise-Induced

ArticleYear
Sodium cromoglycate and verapamil alone and in combination in exercise induced asthma.
    British medical journal (Clinical research ed.), 1983, Feb-19, Volume: 286, Issue:6365

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Drug Therapy, Combination; Female; Humans;

1983
Calcium antagonists in exercise-induced asthma.
    British medical journal (Clinical research ed.), 1981, Mar-21, Volume: 282, Issue:6268

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Fema

1981
Comparison of the effects of inhaled calcium antagonist verapamil, sodium cromoglycate and ipratropium bromide on exercise-induced bronchoconstriction in children with asthma.
    European journal of pediatrics, 1987, Volume: 146, Issue:4

    Topics: Administration, Inhalation; Adolescent; Airway Resistance; Asthma; Asthma, Exercise-Induced; Atropin

1987
Effects of different dosages of the calcium antagonist verapamil in exercise- and methacholine-induced bronchospasm in children with chronic asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1987, Volume: 24, Issue:2

    Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Female; Forced Exp

1987
Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation.
    Clinical allergy, 1985, Volume: 15, Issue:6

    Topics: Asthma, Exercise-Induced; Bronchial Spasm; Cromolyn Sodium; Female; Humans; Hyperventilation; Male;

1985

Other Studies

4 other studies available for verapamil and Asthma, Exercise-Induced

ArticleYear
Calcium channel blocking agents in bronchial hyperreactivity.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; C

1984
The use of cromolyn in the management of hyperreactive airways and exercise.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2

    Topics: Adult; Aerosols; Angioedema; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Child; Cold Temperat

1984
Use of inhaled calcium channel blocking agents in the treatment of asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Aerosols; Airway Resistance; Allergens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Test

1984
Calcium antagonists in experimental asthma.
    Clinical allergy, 1982, Volume: 12 Suppl

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl

1982