verapamil has been researched along with Arthritis, Rheumatoid in 2 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was carried out to examine the effect of rheumatoid arthritis (RA) on the pharmacokinetics and pharmacodynamics of verapamil." | 9.09 | Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis. ( Jamali, F; Mayo, PR; Russell, AS; Skeith, K, 2000) |
| "Active rheumatoid arthritis (RA), obesity, and old age are associated with reduced responsiveness to the calcium channel antagonist verapamil despite increased drug concentrations." | 7.75 | Influence of controlled rheumatoid arthritis on the action and disposition of verapamil: focus on infliximab. ( Ihejirika, B; Jamali, F; Lewanczuk, RZ; Ling, S; Russell, AS, 2009) |
| " This study was carried out to examine the effect of rheumatoid arthritis (RA) on the pharmacokinetics and pharmacodynamics of verapamil." | 5.09 | Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis. ( Jamali, F; Mayo, PR; Russell, AS; Skeith, K, 2000) |
| "Active rheumatoid arthritis (RA), obesity, and old age are associated with reduced responsiveness to the calcium channel antagonist verapamil despite increased drug concentrations." | 3.75 | Influence of controlled rheumatoid arthritis on the action and disposition of verapamil: focus on infliximab. ( Ihejirika, B; Jamali, F; Lewanczuk, RZ; Ling, S; Russell, AS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ling, S | 1 |
| Lewanczuk, RZ | 1 |
| Russell, AS | 2 |
| Ihejirika, B | 1 |
| Jamali, F | 2 |
| Mayo, PR | 1 |
| Skeith, K | 1 |
1 trial available for verapamil and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis.
Topics: Adult; Area Under Curve; Arthritis, Rheumatoid; Calcium Channel Blockers; Female; Humans; Interleuki | 2000 |
1 other study available for verapamil and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Influence of controlled rheumatoid arthritis on the action and disposition of verapamil: focus on infliximab.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; Biological Av | 2009 |