verapamil has been researched along with Apoplexy in 30 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.33) | 18.2507 |
2000's | 15 (50.00) | 29.6817 |
2010's | 12 (40.00) | 24.3611 |
2020's | 2 (6.67) | 2.80 |
Authors | Studies |
---|---|
Anger, T | 1 |
Madge, DJ | 1 |
Mulla, M | 1 |
Riddall, D | 1 |
Redondo, M | 1 |
Zarruk, JG | 1 |
Ceballos, P | 1 |
Pérez, DI | 1 |
Pérez, C | 1 |
Perez-Castillo, A | 1 |
Moro, MA | 1 |
Brea, J | 1 |
Val, C | 1 |
Cadavid, MI | 1 |
Loza, MI | 1 |
Campillo, NE | 1 |
Martínez, A | 1 |
Gil, C | 1 |
Sava, RI | 1 |
Chen, YE | 1 |
Smith, SM | 2 |
Gong, Y | 3 |
Cooper-DeHoff, RM | 5 |
Keeley, EC | 1 |
Pepine, CJ | 9 |
Handberg, EM | 2 |
Bobenko, AI | 1 |
Heller, S | 1 |
Schmitt, N | 1 |
Cherdtrakulkiat, R | 1 |
Lawung, R | 1 |
Nabu, S | 1 |
Tantimavanich, S | 1 |
Sinthupoom, N | 1 |
Prachayasittikul, S | 1 |
Prachayasittikul, V | 1 |
Zhang, B | 1 |
Wu, C | 1 |
Zhang, Z | 2 |
Yan, K | 1 |
Li, C | 2 |
Li, Y | 5 |
Li, L | 3 |
Zheng, C | 1 |
Xiao, Y | 1 |
He, D | 1 |
Zhao, F | 1 |
Su, JF | 1 |
Lun, SM | 1 |
Hou, YJ | 1 |
Duan, LJ | 1 |
Wang, NC | 1 |
Shen, FF | 1 |
Zhang, YW | 1 |
Gao, ZW | 1 |
Li, J | 5 |
Du, XJ | 1 |
Zhou, FY | 1 |
Yin, Z | 1 |
Zhu, J | 2 |
Yan, D | 1 |
Lou, H | 1 |
Yu, H | 1 |
Feng, C | 1 |
Wang, Z | 1 |
Wang, Y | 4 |
Hu, X | 1 |
Li, Z | 2 |
Shen, Y | 1 |
Hu, D | 1 |
Chen, H | 1 |
Wu, X | 1 |
Duan, Y | 1 |
Zhi, D | 1 |
Zou, M | 2 |
Zhao, Z | 1 |
Zhang, X | 2 |
Yang, X | 2 |
Zhang, J | 2 |
Wang, H | 1 |
Popović, KJ | 1 |
Popović, DJ | 1 |
Miljković, D | 1 |
Lalošević, D | 1 |
Čapo, I | 1 |
Popović, JK | 1 |
Liu, M | 1 |
Song, H | 2 |
Xing, Z | 1 |
Lu, G | 1 |
Chen, D | 1 |
Valentini, AM | 1 |
Di Pinto, F | 1 |
Coletta, S | 1 |
Guerra, V | 1 |
Armentano, R | 1 |
Caruso, ML | 1 |
Gong, J | 1 |
Wang, N | 1 |
Bian, L | 1 |
Wang, M | 1 |
Ye, M | 1 |
Wen, N | 1 |
Fu, M | 1 |
Fan, W | 2 |
Meng, Y | 1 |
Dong, G | 1 |
Lin, XH | 1 |
Liu, HH | 1 |
Gao, DM | 1 |
Cui, JF | 1 |
Ren, ZG | 1 |
Chen, RX | 1 |
Önal, B | 1 |
Özen, D | 1 |
Demir, B | 1 |
Akkan, AG | 1 |
Özyazgan, S | 1 |
Payette, G | 1 |
Geoffroy, V | 1 |
Martineau, C | 1 |
Villemur, R | 1 |
Jameel, T | 1 |
Baig, M | 1 |
Gazzaz, ZJ | 1 |
Tashkandi, JM | 1 |
Al Alhareth, NS | 1 |
Khan, SA | 1 |
Butt, NS | 1 |
Wang, J | 2 |
Geng, Y | 1 |
Zhang, Y | 4 |
Wang, X | 2 |
Liu, J | 2 |
Basit, A | 1 |
Miao, T | 1 |
Liu, W | 1 |
Jiang, W | 1 |
Yu, ZY | 1 |
Wu, L | 2 |
Qu, B | 1 |
Sun, JX | 1 |
Cai, AL | 1 |
Xie, LM | 1 |
Groeneveld, J | 1 |
Ho, SL | 1 |
Mackensen, A | 1 |
Mohtadi, M | 1 |
Laepple, T | 1 |
Genovesi, S | 1 |
Nava, E | 1 |
Bartolucci, C | 1 |
Severi, S | 1 |
Vincenti, A | 1 |
Contaldo, G | 1 |
Bigatti, G | 1 |
Ciurlino, D | 1 |
Bertoli, SV | 1 |
Slovak, JE | 1 |
Hwang, JK | 1 |
Rivera, SM | 1 |
Villarino, NF | 1 |
Li, S | 1 |
Cao, G | 1 |
Ling, M | 1 |
Ji, J | 1 |
Zhao, D | 1 |
Sha, Y | 1 |
Gao, X | 1 |
Liang, C | 2 |
Guo, Q | 1 |
Zhou, C | 1 |
Ma, Z | 1 |
Xu, J | 1 |
Wang, C | 1 |
Zhao, W | 1 |
Xia, X | 1 |
Jiang, Y | 1 |
Peng, J | 1 |
Jia, Z | 1 |
Li, F | 1 |
Chen, X | 2 |
Mo, J | 1 |
Zhang, S | 2 |
Li, X | 2 |
Huang, T | 1 |
Zhu, Q | 1 |
Wang, S | 1 |
Ge, RS | 1 |
Fortunato, G | 1 |
Lin, J | 2 |
Agarwal, PK | 1 |
Kohen, A | 1 |
Singh, P | 1 |
Cheatum, CM | 1 |
Zhu, D | 1 |
Hayman, A | 1 |
Kebede, B | 1 |
Stewart, I | 1 |
Chen, G | 1 |
Frew, R | 1 |
Guo, X | 1 |
Gong, Q | 1 |
Borowiec, J | 1 |
Han, S | 1 |
Zhang, M | 1 |
Willis, M | 1 |
Kreouzis, T | 1 |
Yu, K | 1 |
Chirvony, VS | 1 |
Sekerbayev, KS | 1 |
Pérez-Del-Rey, D | 1 |
Martínez-Pastor, JP | 1 |
Palazon, F | 1 |
Boix, PP | 1 |
Taurbayev, TI | 1 |
Sessolo, M | 1 |
Bolink, HJ | 1 |
Lu, M | 1 |
Lan, Y | 1 |
Xiao, J | 1 |
Song, M | 1 |
Chen, C | 1 |
Huang, Q | 1 |
Cao, Y | 1 |
Ho, CT | 1 |
Qi, B | 1 |
Wang, Q | 1 |
Zhang, W | 1 |
Fang, L | 1 |
Xie, CL | 1 |
Chen, R | 1 |
Yang, S | 1 |
Xia, JM | 1 |
Zhang, GY | 1 |
Chen, CH | 1 |
Yang, XW | 1 |
Domenech-Ximenos, B | 1 |
Garza, MS | 1 |
Prat-González, S | 1 |
Sepúlveda-Martínez, Á | 1 |
Crispi, F | 1 |
Perea, RJ | 1 |
Garcia-Alvarez, A | 1 |
Sitges, M | 1 |
Kalumpha, M | 1 |
Guyo, U | 1 |
Zinyama, NP | 1 |
Vakira, FM | 1 |
Nyamunda, BC | 1 |
Varga, M | 1 |
Drácz, L | 1 |
Kolbenheyer, E | 1 |
Varga, F | 1 |
Patai, ÁV | 1 |
Solymosi, N | 1 |
Patai, Á | 1 |
Kiss, J | 1 |
Gaál, V | 1 |
Nyul, Z | 1 |
Mosdósi, B | 1 |
Valdez, M | 1 |
Moosavi, L | 1 |
Heidari, A | 1 |
Novakovic-Agopian, T | 1 |
Kornblith, E | 1 |
Abrams, G | 1 |
McQuaid, JR | 1 |
Posecion, L | 1 |
Burciaga, J | 1 |
D'Esposito, M | 1 |
Chen, AJW | 1 |
Samy El Gendy, NM | 1 |
Wesolowska, P | 1 |
Georg, D | 1 |
Lechner, W | 1 |
Kazantsev, P | 1 |
Bokulic, T | 1 |
Tedgren, AC | 1 |
Adolfsson, E | 1 |
Campos, AM | 1 |
Alves, VGL | 1 |
Suming, L | 1 |
Hao, W | 1 |
Ekendahl, D | 1 |
Koniarova, I | 1 |
Bulski, W | 1 |
Chelminski, K | 1 |
Samper, JLA | 1 |
Vinatha, SP | 1 |
Rakshit, S | 1 |
Siri, S | 1 |
Tomsejm, M | 1 |
Tenhunen, M | 1 |
Povall, J | 1 |
Kry, SF | 1 |
Followill, DS | 1 |
Thwaites, DI | 1 |
Izewska, J | 1 |
Kang, JH | 1 |
Yoon, Y | 1 |
Song, J | 1 |
Van de Winckel, A | 1 |
Gauthier, L | 1 |
Chao, CT | 1 |
Lee, YH | 1 |
Li, CM | 1 |
Han, DS | 1 |
Huang, JW | 1 |
Huang, KC | 1 |
Ni, L | 1 |
Güttinger, R | 1 |
Triana, CA | 1 |
Spingler, B | 1 |
Baldridge, KK | 1 |
Patzke, GR | 1 |
Shen, X | 1 |
Wang, B | 1 |
Xie, S | 1 |
Deng, W | 1 |
Wu, D | 1 |
Zhang, Q | 1 |
Voskamp, BJ | 1 |
Peelen, MJCS | 1 |
Ravelli, ACJ | 1 |
van der Lee, R | 1 |
Mol, BWJ | 1 |
Pajkrt, E | 1 |
Ganzevoort, W | 1 |
Kazemier, BM | 1 |
Tibrewala, R | 1 |
Bahroos, E | 1 |
Mehrabian, H | 1 |
Foreman, SC | 1 |
Link, TM | 1 |
Pedoia, V | 1 |
Majumdar, S | 1 |
Jablonski, CL | 1 |
Leonard, C | 1 |
Salo, P | 1 |
Krawetz, RJ | 1 |
Yoon, N | 1 |
Hong, SN | 1 |
Cho, JG | 1 |
Jeong, HK | 1 |
Lee, KH | 1 |
Park, HW | 1 |
Barman, S | 1 |
Konai, MM | 1 |
Samaddar, S | 1 |
Haldar, J | 1 |
Mohamed, HSH | 1 |
Li, CF | 1 |
Hu, ZY | 1 |
Deng, Z | 1 |
Chen, LH | 1 |
Su, BL | 1 |
Chu, K | 1 |
Liu, YP | 1 |
Li, YB | 1 |
Zhang, H | 1 |
Xu, C | 1 |
Zou, Z | 1 |
Wu, Z | 1 |
Xia, Y | 1 |
Zhao, P | 1 |
Wang, HT | 1 |
de Biase, S | 1 |
Pellitteri, G | 1 |
Gigli, GL | 1 |
Valente, M | 1 |
Ismael, S | 1 |
Nasoohi, S | 1 |
Yoo, A | 1 |
Mirzahosseini, G | 1 |
Ahmed, HA | 1 |
Ishrat, T | 1 |
Fraser, JF | 2 |
Maniskas, M | 1 |
Trout, A | 1 |
Lukins, D | 1 |
Parker, L | 1 |
Stafford, WL | 1 |
Alhajeri, A | 1 |
Roberts, J | 1 |
Bix, GJ | 2 |
Washam, JB | 1 |
Hellkamp, AS | 1 |
Lokhnygina, Y | 1 |
Piccini, JP | 1 |
Berkowitz, SD | 1 |
Nessel, CC | 1 |
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Breithardt, G | 1 |
Fox, KAA | 1 |
Halperin, JL | 1 |
Hankey, GJ | 1 |
Mahaffey, KW | 1 |
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Patel, MR | 1 |
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Chaudry, I | 1 |
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Handberg, E | 2 |
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Messerli, FH | 5 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
INternational VErapamil SR Trandolapril STudy[NCT00133692] | Phase 4 | 22,000 participants | Interventional | 1997-09-30 | Completed | ||
A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multi-centre Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of Verapamil SR on Preservation of Beta-cell Function (Ver-A-T1D)[NCT04545151] | Phase 2 | 138 participants (Anticipated) | Interventional | 2021-02-08 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for verapamil and Apoplexy
Article | Year |
---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo | 2001 |
Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P | 2019 |
Chronopharmacology of cardiovascular therapy.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Blood Pressu | 2002 |
Protection against stroke and dementia: an update on the latest clinical trial evidence.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl | 2004 |
6 trials available for verapamil and Apoplexy
Article | Year |
---|---|
Intra-arterial verapamil post-thrombectomy is feasible, safe, and neuroprotective in stroke.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Brain Ischemia; Cell Death; Cells, | 2017 |
Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial).
Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Diltiazem | 2017 |
Verapamil-sustained release-based treatment strategy is equivalent to atenolol-based treatment strategy at reducing cardiovascular events in patients with prior myocardial infarction: an INternational VErapamil SR-Trandolapril (INVEST) substudy.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Atenol | 2008 |
Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Coronary Artery Disease; Coronary Disease; | 2009 |
Dogma disputed: can aggressively lowering blood pressure in hypertensive patients with coronary artery disease be dangerous?
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cause of Death; Coronary Artery Disease; Di | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
20 other studies available for verapamil and Apoplexy
Article | Year |
---|---|
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.
Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease | 2012 |
Risk and Blood Pressure Control Rates Across the Spectrum of Coronary Artery Disease in Hypertensive Women: An Analysis from The INternational VErapamil SR-Trandolapril STudy (INVEST).
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Cha | 2020 |
Verapamil as an Adjunct Therapy to Reduce tPA Toxicity in Hyperglycemic Stroke: Implication of TXNIP/NLRP3 Inflammasome.
Topics: Animals; Carrier Proteins; Drug Therapy, Combination; Fibrinolytic Agents; Hyperglycemia; Male; Mice | 2021 |
S-oxiracetam protect against ischemic stroke via alleviating blood brain barrier dysfunction in rats.
Topics: Animals; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cla | 2017 |
A Young Woman With A History of Stroke and Recurrent Migraine Headaches.
Topics: Adult; Anti-Arrhythmia Agents; Biopsy; CADASIL; Female; Humans; Magnetic Resonance Imaging; Migraine | 2019 |
Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke.
Topics: Acute Disease; Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Calcium Channel Blockers; Cell | 2016 |
Calcium channel blocker use is associated with lower fasting serum glucose among adults with diabetes from the REGARDS study.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus; Dose-Response R | 2016 |
Basilar artery occlusion in a child treated successfully with mechanical thrombectomy using ADAPT.
Topics: Arterial Occlusive Diseases; Basilar Artery; Cerebral Angiography; Child; Combined Modality Therapy; | 2016 |
Mortality Risk Associated With Resistant Hypertension Among Women: Analysis from Three Prospective Cohorts Encompassing the Spectrum of Women's Heart Disease.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Artery Disease; Drug Resistance; Fema | 2016 |
Proteomic identification of haptoglobin as a stroke plasma biomarker in spontaneously hypertensive stroke-prone rats.
Topics: Animals; Biomarkers; Blood Proteins; Haptoglobins; Hypertension; Male; Proteomics; Rats; Rats, Inbre | 2008 |
Overlapping features of eclampsia and postpartum angiopathy.
Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipi | 2009 |
Recurrent stroke due to a novel voltage sensor mutation in Cav2.1 responds to verapamil.
Topics: Calcium Channels; Calcium Channels, N-Type; Child; Female; Humans; Mutation; Secondary Prevention; S | 2011 |
Harmful effects of NSAIDs among patients with hypertension and coronary artery disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Celec | 2011 |
Cerebral vasoconstriction and stroke after use of serotonergic drugs.
Topics: Cerebrovascular Circulation; Humans; Migraine Disorders; Serotonin Agents; Stroke; Vasoconstriction; | 2002 |
VISP and INVEST.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; | 2004 |
[Stroke and other thromboembolic complications of atrial fibrillation. Part v. The use of drugs without antithrombotic or antiarrhythmic properties.].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Humans; Stroke; Verapamil | 2004 |
Adult hypertension: reducing cardiovascular morbidity and mortality.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking | 2005 |
Predictors of adverse outcome among patients with hypertension and coronary artery disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium | 2006 |
Predicting stroke risk in hypertensive patients with coronary artery disease: a report from the INVEST.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Black People; Coronary Artery Disease; D | 2008 |
Stroke-prone spontaneously hypertensive rats lose their ability to auto-regulate cerebral blood flow prior to stroke.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diet; Homeostasis; Hypertension; In Vitro Tech | 1999 |