verapamil has been researched along with Anoxia, Brain in 9 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an in vitro model of cerebral ischemia we investigated the functional consequences of repeated hypoxias and the potential protective effect of the N-methyl-D-aspartate (NMDA) receptor antagonist D-2-amino-5-phosphonovaleric acid (D-APV) and the calcium channel blocker verapamil in preventing the expression of pathophysiological activity." | 3.68 | Role of NMDA receptors and voltage-activated calcium channels in an in vitro model of cerebral ischemia. ( Heinemann, U; Kral, T; Luhmann, HJ; Mittmann, T, 1993) |
| "To provide evidence to support the calcium hypothesis of cerebral ischemia, we examined the effects of extracellular calcium and calcium antagonists (verapamil, flunarizine, nicardipine) on in vitro 'ischemia' using guinea pig hippocampal slices." | 3.68 | Effects of calcium and calcium antagonists against deprivation of glucose and oxygen in guinea pig hippocampal slices. ( Amagasa, M; Ogawa, A; Yoshimoto, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fraser, JF | 1 |
| Maniskas, M | 1 |
| Trout, A | 1 |
| Lukins, D | 1 |
| Parker, L | 1 |
| Stafford, WL | 1 |
| Alhajeri, A | 1 |
| Roberts, J | 1 |
| Bix, GJ | 1 |
| Fang, W | 1 |
| Lv, P | 1 |
| Geng, X | 1 |
| Shang, E | 1 |
| Yang, Q | 1 |
| Sha, L | 1 |
| Li, Y | 1 |
| Oka, M | 1 |
| Itoh, Y | 1 |
| Wada, M | 1 |
| Yamamoto, A | 1 |
| Fujita, T | 1 |
| Proctor, HJ | 1 |
| Palladino, GW | 1 |
| Fillipo, D | 1 |
| Sanders, R | 1 |
| Clincke, GH | 1 |
| Wauquier, A | 1 |
| White, BC | 1 |
| Winegar, CD | 1 |
| Wilson, RF | 1 |
| Krause, GS | 1 |
| Karasawa, A | 1 |
| Kumada, Y | 1 |
| Yamada, K | 1 |
| Shuto, K | 1 |
| Nakamizo, N | 1 |
| Kral, T | 1 |
| Luhmann, HJ | 1 |
| Mittmann, T | 1 |
| Heinemann, U | 1 |
| Amagasa, M | 1 |
| Ogawa, A | 1 |
| Yoshimoto, T | 1 |
1 trial available for verapamil and Anoxia, Brain
| Article | Year |
|---|---|
Intra-arterial verapamil post-thrombectomy is feasible, safe, and neuroprotective in stroke.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Brain Ischemia; Cell Death; Cells, | 2017 |
8 other studies available for verapamil and Anoxia, Brain
| Article | Year |
|---|---|
Penetration of verapamil across blood brain barrier following cerebral ischemia depending on both paracellular pathway and P-glycoprotein transportation.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Bloo | 2013 |
A comparison of Ca2+ channel blocking mode between gabapentin and verapamil: implication for protection against hypoxic injury in rat cerebrocortical slices.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-T | 2003 |
Cerebral high energy phosphates after hypoxic-hypotension: effect of verapamil and nifedipine.
Topics: Adenosine Triphosphate; Animals; Brain; Cerebrovascular Circulation; Hypotension; Hypoxia, Brain; Ma | 1984 |
Pharmacological protection against hypoxia-induced effects on medium-term memory in a two-way avoidance paradigm.
Topics: Animals; Avoidance Learning; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Dose-Response R | 1984 |
Calcium blockers in cerebral resuscitation.
Topics: Animals; Calcium Channel Blockers; Cardiopulmonary Bypass; Cerebral Cortex; Cerebrovascular Circulat | 1983 |
Protective effect of flunarizine against cerebral hypoxia-anoxia in mice and rats.
Topics: Animals; Cinnarizine; Flunarizine; Hypoxia, Brain; Male; Mice; Mice, Inbred Strains; Pentobarbital; | 1982 |
Role of NMDA receptors and voltage-activated calcium channels in an in vitro model of cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Calcium; Calcium Channels; Electrophysiology; | 1993 |
Effects of calcium and calcium antagonists against deprivation of glucose and oxygen in guinea pig hippocampal slices.
Topics: Action Potentials; Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Disease Models, Anima | 1990 |