verapamil has been researched along with Anoxemia in 120 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Noncardiogenic pulmonary edema has not been (to our knowledge) previously reported associated with a verapamil overdose." | 7.69 | Noncardiogenic pulmonary edema complicating massive verapamil overdose. ( Frumin, H; Leesar, MA; Martyn, R; Talley, JD, 1994) |
| " Pretreatment of animals with verapamil did not affect the abnormality of glucose metabolism but abolished the associated acidosis." | 7.68 | Verapamil prevents cerebral acidosis during moderate hypoxia and hypotension. ( Lockwood, AH; Yap, EW, 1991) |
| "Hypoxia-induced stimulation of the rate of von Willebrand factor (vWF) release from human umbilical vein endothelial cells in culture, and the influence of the calcium antagonist verapamil, was studied using a system in which a pO2 of 20 mm Hg was achieved over 60 min." | 7.68 | Hypoxia-induced von Willebrand factor release is blocked by verapamil. ( Blake, D; Cunningham, J; Stevens, CR; Wilkie, ME, 1992) |
| " We have used an isolated buffer-perfused preparation of the rabbit ear to investigate the effects of hypoxia and inhibition of endothelium-derived relaxing factor (EDRF) synthesis on the vasodilator responses to the potassium channel opener, levcromakalim (the active (-)-enantiomer of cromakalim)." | 7.68 | Modulation of vasodilatation to levcromakalim by hypoxia and EDRF in the rabbit isolated ear: a comparison with pinacidil, sodium nitroprusside and verapamil. ( Griffith, TM; Randall, MD, 1993) |
| " This report compares the activity of flunarizine and verapamil, another calcium entry blocking drug, on the central nervous system (CNS) and peripheral consequences of cytotoxic hypoxia induced by high and low doses of KCN." | 7.67 | Flunarizine and verapamil: effects on central nervous system and peripheral consequences of cytotoxic hypoxia in rats. ( Dubinsky, B; Ritchie, DM; Sierchio, JN; Temple, DE, 1984) |
| "To test whether verapamil protects myocardial high-energy phosphate content during hypoxia by reducing pre-hypoxic cardiac work or secondary to metabolic events that occur during hypoxia, we compared the relation between myocardial performance and high-energy phosphate content during normoxia, hypoxia and reoxygenation using 31P NMR spectroscopy in isolated, isovolumic buffer-perfused rat hearts." | 7.67 | Verapamil attenuates ATP depletion during hypoxia: 31P NMR studies of the isolated rat heart. ( Ingwall, JS; Neubauer, S, 1989) |
| "Myocardial hypoxia, induced by arrest of the artificial ventilation of anaesthetized open-chest rats, was utilized in order to study some aspects of the regulation of myocardial glycogen metabolism." | 7.67 | [Enzyme activity of cardiac glycogen metabolism: study of an in situ hypoxia protocol in the rat]. ( Grably, S; Rossi, A; Verdys, M, 1989) |
| "Changes in cAMP content of tissues of lung, heart and aorta and in blood plasma of rats during chronic hypoxia and administration of verapamil were determined and investigated." | 7.67 | Effects of chronic hypoxia and verapamil on cAMP content in tissues and blood plasma. ( Cai, YN; Yuan, XJ, 1989) |
| " We have investigated the effect of the calcium antagonist verapamil upon the polycythaemic response to hypoxia in rats." | 7.67 | Effect of verapamil on polycythaemia secondary to hypoxia in rats. ( Cameron, IR; Douglas, AR; Moore-Gillon, JC; Sheldon, JW, 1987) |
| " The bi-fluorophenyl-piperazine derivatives, lidoflazine and flunarizine, enhanced the reactive hyperemia elicited by a brief (30 s) anoxic challenge." | 7.67 | The effects of lidoflazine and flunarizine on cerebral reactive hyperemia. ( DeLong, RE; Phillis, JW; Towner, JK, 1985) |
| "Adult male Wistar rats were used for studying the effect of Ca2+ antagonist verapamil on pulmonary hypertension, right ventricular hypertrophy and the medial thickness of pulmonary arterioles, induced by intermittent high altitude (IHA) hypoxia." | 7.66 | Effect of verapamil on pulmonary hypertension and right ventricular hypertrophy induced in rats by intermittent high altitude hypoxia. ( Ostádal, B; Pelouch, V; Procházka, J; Ressl, J; Urbanová, D; Widimský, J, 1981) |
| "In calves with hypoxic pulmonary hypertension, resistance was reduced by 40 +/- 3% with normoxia, 19 +/- 4% with verapamil, and 60 +/- 1% with hexoprenaline." | 7.65 | Reduction of bovine pulmonary hypertension by normoxia, verapamil and hexoprenaline. ( Grover, RF; McMurtry, IF; Reeves, JT; Will, DH, 1977) |
| " At their maximal safe dosage in humans, methysergide and verapamil suggest no role for serotonin and calcium ions." | 6.66 | Ventilatory response to sustained hypoxia: effect of methysergide and verapamil. ( Anthonisen, NR; Balakumar, M; Easton, PA; Filuk, R; Long, GR, 1989) |
| "1." | 5.29 | Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs. ( Boulanger, CM; Kirchengast, M; Lee, JJ; Vanhoutte, PM, 1996) |
| "Verapamil (0." | 5.28 | Effects of manganese chloride, verapamil, and hypoxia on the rate-dependent increase in internal longitudinal resistance of rabbit myocardium. ( Alvarez, J; Dorticós, F; Morlans, J; Rousseau, G, 1989) |
| "Pretreatment with verapamil inhibited thromboxane synthesis, the rise in pulmonary artery pressure and the hypoxia without affecting the transient leukopenia." | 5.27 | Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep. ( Davies, BJ; McDonald, JW; Noulty, EJ; Pisters, LL; Smallbone, BW; Taylor, NE, 1986) |
| "Acute hypoxia did not alter the pharmacokinetics of theophylline [half-life+/-SD: 9." | 5.11 | Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m). ( Bärtsch, P; Burhenne, J; Dehnert, C; Göggelmann, C; Haefeli, WE; Menold, E; Mikus, G; Riedel, KD; Streit, M, 2005) |
| " Biochemical evidence suggests that pulmonary vasoconstriction results from the transmembrane flux of calcium into vascular smooth muscle; accordingly, the pulmonary pressor responses in experimental hypoxic pulmonary hypertension can be attenuated by verapamil and nifedipine." | 4.77 | Therapeutic application of calcium-channel antagonists for pulmonary hypertension. ( Packer, M, 1985) |
| "Pregnancy increased diazoxide, but not verapamil-induced relaxations." | 3.76 | Role of KATP and L-type Ca2+ channel activities in regulation of ovine uterine vascular contractility: effect of pregnancy and chronic hypoxia. ( Longo, LD; Xiao, D; Zhang, L, 2010) |
| "Noncardiogenic pulmonary edema has not been (to our knowledge) previously reported associated with a verapamil overdose." | 3.69 | Noncardiogenic pulmonary edema complicating massive verapamil overdose. ( Frumin, H; Leesar, MA; Martyn, R; Talley, JD, 1994) |
| "Hypoxia-induced stimulation of the rate of von Willebrand factor (vWF) release from human umbilical vein endothelial cells in culture, and the influence of the calcium antagonist verapamil, was studied using a system in which a pO2 of 20 mm Hg was achieved over 60 min." | 3.68 | Hypoxia-induced von Willebrand factor release is blocked by verapamil. ( Blake, D; Cunningham, J; Stevens, CR; Wilkie, ME, 1992) |
| " We have used an isolated buffer-perfused preparation of the rabbit ear to investigate the effects of hypoxia and inhibition of endothelium-derived relaxing factor (EDRF) synthesis on the vasodilator responses to the potassium channel opener, levcromakalim (the active (-)-enantiomer of cromakalim)." | 3.68 | Modulation of vasodilatation to levcromakalim by hypoxia and EDRF in the rabbit isolated ear: a comparison with pinacidil, sodium nitroprusside and verapamil. ( Griffith, TM; Randall, MD, 1993) |
| " Pretreatment of animals with verapamil did not affect the abnormality of glucose metabolism but abolished the associated acidosis." | 3.68 | Verapamil prevents cerebral acidosis during moderate hypoxia and hypotension. ( Lockwood, AH; Yap, EW, 1991) |
| "In anesthetized and thoracotomized 20 adult dogs under artificial respiration, the effects of calcium blockers (nifedipine, diltiazem and verapamil) on the mechanics of the left and right cardiac pumps under acute hypoxia were observed." | 3.68 | [Effects of calcium blockers on the performance of left and right ventricles during acute hypoxia]. ( Gu, LM; Xiao, Y; Yuan, F; Zhou, ZN, 1992) |
| "Effects of "Qi-Xue" injection (Panax ginseng, Astragalus monogholicus, Angelica sinensis), verapamil (Vp, calcium antagonist) and their combination on pulmonary arterial pressure (PAP) and heart function were studied in rats exposed to chronic hypoxia." | 3.68 | [Prevention of hypoxic pulmonary hypertension with "qi-xue" injection]. ( Zhao, L, 1990) |
| "Cardiovascular responses to the calcium antagonists verapamil and nifedipine were evaluated in a piglet model of hypoxic pulmonary hypertension." | 3.67 | The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet. ( Bancalari, E; Dickstein, PJ; Goldberg, RN; Trindade, O, 1984) |
| " This report compares the activity of flunarizine and verapamil, another calcium entry blocking drug, on the central nervous system (CNS) and peripheral consequences of cytotoxic hypoxia induced by high and low doses of KCN." | 3.67 | Flunarizine and verapamil: effects on central nervous system and peripheral consequences of cytotoxic hypoxia in rats. ( Dubinsky, B; Ritchie, DM; Sierchio, JN; Temple, DE, 1984) |
| "To test whether verapamil protects myocardial high-energy phosphate content during hypoxia by reducing pre-hypoxic cardiac work or secondary to metabolic events that occur during hypoxia, we compared the relation between myocardial performance and high-energy phosphate content during normoxia, hypoxia and reoxygenation using 31P NMR spectroscopy in isolated, isovolumic buffer-perfused rat hearts." | 3.67 | Verapamil attenuates ATP depletion during hypoxia: 31P NMR studies of the isolated rat heart. ( Ingwall, JS; Neubauer, S, 1989) |
| "Changes in cAMP content of tissues of lung, heart and aorta and in blood plasma of rats during chronic hypoxia and administration of verapamil were determined and investigated." | 3.67 | Effects of chronic hypoxia and verapamil on cAMP content in tissues and blood plasma. ( Cai, YN; Yuan, XJ, 1989) |
| "88 mM Amytal (amobarbital), hypoxia (95% N2-5% CO2), or 12 microM adenosine in the presence and absence of 2." | 3.67 | Relationship of myocardial metabolism and coronary flow: dependence on extracellular calcium. ( Erecińska, M; Rumsey, WL; Wilson, DF, 1987) |
| "Myocardial hypoxia, induced by arrest of the artificial ventilation of anaesthetized open-chest rats, was utilized in order to study some aspects of the regulation of myocardial glycogen metabolism." | 3.67 | [Enzyme activity of cardiac glycogen metabolism: study of an in situ hypoxia protocol in the rat]. ( Grably, S; Rossi, A; Verdys, M, 1989) |
| "The objectives of this study were to examine the independent and combined effects of beta blockade (practolol) and calcium channel blockade (verapamil) on cardiac responses to hypoxia in the neonate." | 3.67 | Potentiation by calcium channel blockade of hypoxic myocardial depression in the neonate. ( Downing, SE, 1985) |
| " We have investigated the effect of the calcium antagonist verapamil upon the polycythaemic response to hypoxia in rats." | 3.67 | Effect of verapamil on polycythaemia secondary to hypoxia in rats. ( Cameron, IR; Douglas, AR; Moore-Gillon, JC; Sheldon, JW, 1987) |
| "In order to determine the influence of calcium on erythropoietin release in response to hypoxia, the effects of the calcium entry blocker verapamil on erythropoietin production were investigated." | 3.67 | Enhanced erythropoietin production by calcium entry blockers in rats exposed to hypoxia. ( Brookins, J; Fisher, JW; McGonigle, RJ; Pegram, BL, 1987) |
| "Effects of hypoxia on atrioventricular conduction were investigated in the Langendorff-perfused isolated heart of the rabbit with various extracellular calcium concentrations ([Ca2+]) as well as in the presence of verapamil, nifedipine, N-(6-aminohexyl)-5-chloro-1-naphthalenesulphonamide (W-7) and chlorpromazine." | 3.67 | Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia. ( Anno, T; Kodama, I; Shibata, S; Toyama, J; Yamada, K, 1986) |
| "9 microM), the Ca++ channel blocker verapamil (2 microM), and CaCl2 (6 mM) on a model of heart damage, hypoxia/reoxygenation of isolated guinea-pig hearts." | 3.67 | TEA prevents the decline of the duration of the action potential in hypoxic cardiac muscle. ( Asano, T; Kasuya, Y; Shigenobu, K, 1985) |
| " The bi-fluorophenyl-piperazine derivatives, lidoflazine and flunarizine, enhanced the reactive hyperemia elicited by a brief (30 s) anoxic challenge." | 3.67 | The effects of lidoflazine and flunarizine on cerebral reactive hyperemia. ( DeLong, RE; Phillis, JW; Towner, JK, 1985) |
| "Experiments were undertaken to determine if drugs (verapamil, propranolol, and methylprednisolone sodium saccinate) that protect the fine ultrastructure of heart muscle against damage caused by hypoxia, protect mitochondrial function." | 3.66 | Pharmacological protection of mitochondrial function in hypoxic heart muscle: Effect of verapamil, propranolol, and methylprednisolone. ( Fassold, E; Nayler, WG; Yepez, C, 1978) |
| "Adult male Wistar rats were used for studying the effect of Ca2+ antagonist verapamil on pulmonary hypertension, right ventricular hypertrophy and the medial thickness of pulmonary arterioles, induced by intermittent high altitude (IHA) hypoxia." | 3.66 | Effect of verapamil on pulmonary hypertension and right ventricular hypertrophy induced in rats by intermittent high altitude hypoxia. ( Ostádal, B; Pelouch, V; Procházka, J; Ressl, J; Urbanová, D; Widimský, J, 1981) |
| " The vascular reactivity of isolated, blood-perfused rat lungs was established by eliciting pressor responses to airway hypoxia and to intraarterial angiotensin II." | 3.66 | Inhibitors of oxidative ATP production cause transient vasoconstriction and block subsequent pressor responses in rat lungs. ( McMurtry, IF; Rounds, S, 1981) |
| "The influence of an increased Ca concentration on reactive hyperemia, work induced vasodilation and pharmacologically induced dilation (adenosine, nifedipine, verapamil) was studied in the blood perfused gastrocnemius of dogs." | 3.65 | [The effect of increased extracellular calcium concentration on the hypoxic and pharmacologic hyperemia of skeletal muscle]. ( Marten, W; Meyer, VU; Raff, WK; Schiffer, W, 1975) |
| "In calves with hypoxic pulmonary hypertension, resistance was reduced by 40 +/- 3% with normoxia, 19 +/- 4% with verapamil, and 60 +/- 1% with hexoprenaline." | 3.65 | Reduction of bovine pulmonary hypertension by normoxia, verapamil and hexoprenaline. ( Grover, RF; McMurtry, IF; Reeves, JT; Will, DH, 1977) |
| " At their maximal safe dosage in humans, methysergide and verapamil suggest no role for serotonin and calcium ions." | 2.66 | Ventilatory response to sustained hypoxia: effect of methysergide and verapamil. ( Anthonisen, NR; Balakumar, M; Easton, PA; Filuk, R; Long, GR, 1989) |
| "IPA treated with thapsigargin (1 microM) in Ca2+-free solution to deplete Ca2+ stores showed sustained constriction upon re-exposure to Ca2+ and an increase in the rate of Mn2+ influx, suggesting capacitative Ca2+ entry." | 1.31 | Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat. ( Aaronson, PI; Hague, D; Robertson, TP; Ward, JP, 2000) |
| "1." | 1.29 | Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs. ( Boulanger, CM; Kirchengast, M; Lee, JJ; Vanhoutte, PM, 1996) |
| "In a second group (n = 9), hypoxemia induced marked significant decreases in GFR, RBF and urine flow rate (-22 +/- 5%, -18 +/- 6% and -34 +/- 7% respectively)." | 1.29 | Protection from hypoxemic renal dysfunction by verapamil and manganese in the rabbit. ( Guignard, JP; Heumann, C; Semama, D, 1995) |
| "Verapamil's inhibition was rapid in onset and disappearance; changes in glucose transport rate were detectable when verapamil was added to or removed from the incubation medium 15 min prior to measurement of glucose transport." | 1.28 | Diverse effects of calcium channel blockers on skeletal muscle glucose transport. ( Briggs-Tung, C; Cartee, GD; Holloszy, JO, 1992) |
| "Verapamil (0." | 1.28 | Effects of manganese chloride, verapamil, and hypoxia on the rate-dependent increase in internal longitudinal resistance of rabbit myocardium. ( Alvarez, J; Dorticós, F; Morlans, J; Rousseau, G, 1989) |
| " AB and hypoxia/reoxygenation caused additive, not synergistic, LDH release whereas CS-AB had no adverse effect." | 1.28 | Direct amphotericin B-mediated tubular toxicity: assessments of selected cytoprotective agents. ( Bredl, CR; Schimpf, BA; Zager, RA, 1992) |
| " No clinically useful benefit was found with verapamil in the dosage used in this group of patients and the value of calcium antagonists in the treatment of patients with chronic obstructive lung disease requires further clarification." | 1.27 | Effects of verapamil on pulmonary haemodynamics during hypoxaemia, at rest, and during exercise in patients with chronic obstructive pulmonary disease. ( Blair, GP; Brown, SE; King, RR; Light, RW; Linden, GS; Stansbury, DW, 1983) |
| "Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue." | 1.27 | Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia. ( Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS, 1986) |
| "Pretreatment with verapamil inhibited thromboxane synthesis, the rise in pulmonary artery pressure and the hypoxia without affecting the transient leukopenia." | 1.27 | Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep. ( Davies, BJ; McDonald, JW; Noulty, EJ; Pisters, LL; Smallbone, BW; Taylor, NE, 1986) |
| "When monensin was applied simultaneously with ouabain, there was a rapid increase in cellular Na+ and loss of cellular K+." | 1.27 | Action of the Na+ ionophore monensin on vascular smooth muscle of guinea-pig aorta. ( Chihara, S; Kishimoto, T; Ozaki, H; Umeno, H; Urakawa, N, 1984) |
| "Verapamil was more active than nifedipine in both models." | 1.27 | Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists. ( Jacobs, LW; Rosenberger, LB; Stanton, HC, 1984) |
| "After 45 min of anoxia and a 4- to 6-hr incubation in normal Ca++-containing media, cells from all segments were dead." | 1.27 | Beneficial effects of calcium channel blockers and calmodulin binding drugs on in vitro renal cell anoxia. ( Schrier, RW; Schwertschlag, U; Wilson, P, 1986) |
| "Propranolol was either added at the start of the hypoxic perfusion or the rabbit were pretreated with it." | 1.26 | [Creatine phosphokinase release from perfused cardiac muscle under hypoxic conditions. Effect of propranolol, verapamil, reserpine and deslanoside]. ( Bongrani, S; Ferrari, R, 1979) |
| "In the isolated rat heart, anoxia or ischemia do not induce important ventricular tachyarrhythmias (VTAs)." | 1.26 | Inhibitory effect of anoxia on reperfusion- and digitalis-induced ventricular tachyarrhythmias. ( Carbonin, P; Di Gennaro, M; Valle, R; Weisz, AM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (70.00) | 18.7374 |
| 1990's | 27 (22.50) | 18.2507 |
| 2000's | 6 (5.00) | 29.6817 |
| 2010's | 3 (2.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, TX | 1 |
| Liu, RH | 1 |
| Wang, XB | 1 |
| Luo, J | 1 |
| Luo, JG | 1 |
| Kong, LY | 1 |
| Yang, MH | 1 |
| Meng, F | 1 |
| To, WK | 1 |
| Gu, Y | 1 |
| Mampreso, E | 1 |
| Maggioni, F | 1 |
| Viaro, F | 1 |
| Disco, C | 1 |
| Zanchin, G | 1 |
| Xiao, D | 1 |
| Longo, LD | 1 |
| Zhang, L | 1 |
| Strielkov, IeV | 1 |
| Frantsuzova, SB | 1 |
| Khromov, OS | 1 |
| Barac-Nieto, M | 1 |
| Constantinescu, A | 1 |
| Pina-Benabou, MH | 1 |
| Rozental, R | 1 |
| Streit, M | 1 |
| Göggelmann, C | 1 |
| Dehnert, C | 1 |
| Burhenne, J | 1 |
| Riedel, KD | 1 |
| Menold, E | 1 |
| Mikus, G | 1 |
| Bärtsch, P | 1 |
| Haefeli, WE | 1 |
| Dukes, ID | 1 |
| Vaughan Williams, EM | 1 |
| Metsä-Ketelä, T | 2 |
| Laustiola, K | 2 |
| Lilius, EM | 1 |
| Vapaatalo, H | 2 |
| Gracián Gómez, M | 1 |
| Rodríguez Caamaño, J | 1 |
| Guía Torrent, JM | 1 |
| Ostádal, B | 2 |
| Widimský, J | 2 |
| Urbanová, D | 2 |
| Procházka, J | 2 |
| Pelouch, V | 2 |
| Ressl, J | 1 |
| Sys, SU | 1 |
| Housmans, PR | 1 |
| Van Ocken, ER | 1 |
| Brutsaert, DL | 1 |
| Milstein, JM | 1 |
| Goetzman, BW | 1 |
| Dickstein, PJ | 1 |
| Trindade, O | 1 |
| Goldberg, RN | 1 |
| Bancalari, E | 1 |
| Young, TE | 1 |
| Lundquist, LJ | 1 |
| Chesler, E | 1 |
| Weir, EK | 1 |
| Brown, SE | 1 |
| Linden, GS | 1 |
| King, RR | 1 |
| Blair, GP | 1 |
| Stansbury, DW | 1 |
| Light, RW | 1 |
| Scherer, R | 1 |
| Wendt, M | 1 |
| Schneider, U | 1 |
| Kober, S | 1 |
| Lawin, P | 1 |
| Cheung, JY | 1 |
| Leaf, A | 1 |
| Bonventre, JV | 1 |
| Dubinsky, B | 1 |
| Sierchio, JN | 1 |
| Temple, DE | 1 |
| Ritchie, DM | 1 |
| Rosenberger, LB | 1 |
| Jacobs, LW | 1 |
| Stanton, HC | 1 |
| Kovách, AG | 3 |
| Dóra, E | 2 |
| Ozaki, H | 1 |
| Kishimoto, T | 1 |
| Chihara, S | 1 |
| Umeno, H | 1 |
| Urakawa, N | 1 |
| Stanbrook, HS | 1 |
| Morris, KG | 1 |
| McMurtry, IF | 6 |
| Higgins, TJ | 1 |
| Allsopp, D | 1 |
| Bailey, PJ | 1 |
| Szedlacsek, S | 1 |
| Koller, A | 1 |
| Doorey, AJ | 1 |
| Barry, WH | 1 |
| Kraynack, BJ | 1 |
| Gintautas, J | 1 |
| Kraynack, LL | 1 |
| Havasi, G | 1 |
| Watanabe, Y | 1 |
| Carbonin, P | 1 |
| Di Gennaro, M | 1 |
| Valle, R | 1 |
| Weisz, AM | 1 |
| Gilmour, RF | 1 |
| Zipes, DP | 1 |
| Rounds, S | 1 |
| Cornfield, DN | 1 |
| Stevens, T | 1 |
| Abman, SH | 1 |
| Rodman, DM | 1 |
| Savineau, JP | 1 |
| Gonzalez de la Fuente, P | 1 |
| Marthan, R | 1 |
| Semama, D | 1 |
| Heumann, C | 1 |
| Guignard, JP | 1 |
| Hisatome, I | 1 |
| Arita, M | 1 |
| Wetzels, JF | 1 |
| Yu, L | 1 |
| Wang, X | 1 |
| Kribben, A | 1 |
| Burke, TJ | 1 |
| Schrier, RW | 2 |
| Leesar, MA | 1 |
| Martyn, R | 1 |
| Talley, JD | 1 |
| Frumin, H | 1 |
| Randall, MD | 1 |
| Griffith, TM | 1 |
| Salvaterra, CG | 1 |
| Goldman, WF | 1 |
| Lee, JJ | 1 |
| Boulanger, CM | 1 |
| Kirchengast, M | 1 |
| Vanhoutte, PM | 2 |
| Sanotskaia, NV | 1 |
| Matsievskiĭ, DD | 1 |
| Kurambaev, IaK | 1 |
| Safonov, VA | 1 |
| Marquez, MT | 1 |
| Consolini, A | 1 |
| Bonazzola, P | 1 |
| Ponce-Hornos, JE | 1 |
| Tenthorey, D | 1 |
| de Ribaupierre, Y | 1 |
| Kucera, P | 1 |
| Raddatz, E | 1 |
| Priest, RM | 1 |
| Robertson, TP | 2 |
| Leach, RM | 1 |
| Ward, JP | 2 |
| Lee, YH | 1 |
| Seo, JH | 1 |
| Kang, BS | 1 |
| Hague, D | 1 |
| Aaronson, PI | 1 |
| De Crescenzo, V | 1 |
| Dubuis, E | 1 |
| Constantin, S | 1 |
| Rebocho, M | 1 |
| Girardin, C | 1 |
| Bonnet, P | 1 |
| Vandier, C | 1 |
| Nayler, WG | 3 |
| Yepez, CE | 1 |
| Poole-Wilson, PA | 1 |
| Schurek, HJ | 1 |
| Aulbert, E | 1 |
| Ebel, H | 1 |
| Ferrari, R | 1 |
| Bongrani, S | 1 |
| Fassold, E | 1 |
| Yepez, C | 1 |
| Davidson, A | 1 |
| McMurtry, I | 1 |
| Reeves, JT | 4 |
| Will, DH | 1 |
| Grover, RF | 3 |
| Barer, GR | 1 |
| Mohammed, FH | 1 |
| Sugget, AJ | 1 |
| Grau, A | 1 |
| Slade, A | 1 |
| Meyer, VU | 1 |
| Marten, W | 1 |
| Schiffer, W | 1 |
| Raff, WK | 1 |
| Davidson, AB | 1 |
| Tucker, A | 1 |
| Zhou, ZN | 1 |
| Gu, LM | 1 |
| Yuan, F | 1 |
| Xiao, Y | 1 |
| Wilkie, ME | 1 |
| Stevens, CR | 1 |
| Cunningham, J | 1 |
| Blake, D | 1 |
| Pacini, DJ | 1 |
| Boachie-Ansah, G | 1 |
| Kane, KA | 3 |
| Ohdaira, T | 1 |
| Kobayashi, T | 1 |
| Tanaka, M | 1 |
| Chowdhury, MF | 1 |
| Ahn, B | 1 |
| Masuda, A | 1 |
| Sakakibara, Y | 1 |
| Honda, Y | 1 |
| Zager, RA | 1 |
| Bredl, CR | 1 |
| Schimpf, BA | 1 |
| Konishi, K | 1 |
| Utsunomiya, H | 1 |
| Hashimoto, H | 1 |
| Hirano, M | 1 |
| Cartee, GD | 1 |
| Briggs-Tung, C | 1 |
| Holloszy, JO | 1 |
| Demiryurek, AT | 1 |
| Wadsworth, RM | 2 |
| Poloński, L | 2 |
| Polońska, A | 2 |
| Tendera, M | 2 |
| Wodniecki, J | 2 |
| Krzywiecki, A | 1 |
| Lockwood, AH | 1 |
| Yap, EW | 1 |
| Hasan, NM | 1 |
| Cundall, RB | 1 |
| Adams, GE | 1 |
| Yuan, XJ | 2 |
| Tod, ML | 1 |
| Rubin, LJ | 1 |
| Blaustein, MP | 1 |
| Zhao, L | 1 |
| Adamantidis, MM | 1 |
| Caron, JF | 1 |
| Dupuis, BA | 1 |
| Rumsey, WL | 1 |
| Wilson, DF | 1 |
| Erecińska, M | 1 |
| Grably, S | 1 |
| Verdys, M | 1 |
| Rossi, A | 1 |
| Cai, YN | 1 |
| Neubauer, S | 1 |
| Ingwall, JS | 1 |
| Bhattacharyya, ML | 1 |
| Acharya, S | 1 |
| Lee, SL | 1 |
| Dunn, J | 1 |
| Yu, FS | 1 |
| Fanburg, BL | 1 |
| Long, GR | 1 |
| Filuk, R | 1 |
| Balakumar, M | 1 |
| Easton, PA | 1 |
| Anthonisen, NR | 1 |
| Kjaeve, J | 1 |
| Bjertnaes, LJ | 1 |
| Kwan, YW | 1 |
| Alvarez, J | 1 |
| Rousseau, G | 1 |
| Dorticós, F | 1 |
| Morlans, J | 1 |
| Urbanics, R | 1 |
| Leitold, M | 1 |
| Hader, S | 1 |
| Escoubet, B | 2 |
| Griffaton, G | 2 |
| Lechat, P | 2 |
| Barrett, JA | 1 |
| DePaul Lynch, V | 1 |
| Balkon, J | 1 |
| Smith, RD | 1 |
| Wolf, PS | 1 |
| Cartheuser, CF | 2 |
| Douglas, AR | 1 |
| Moore-Gillon, JC | 1 |
| Sheldon, JW | 1 |
| Cameron, IR | 2 |
| Brezis, M | 1 |
| Shina, A | 1 |
| Kidroni, G | 1 |
| Epstein, FH | 1 |
| Rosen, S | 1 |
| Takeo, S | 1 |
| Tanonaka, K | 1 |
| Tazuma, Y | 1 |
| Fukao, N | 1 |
| Yoshikawa, C | 1 |
| Fukumoto, T | 1 |
| Tanaka, T | 1 |
| Pudelski, J | 1 |
| Kardaszewicz, P | 1 |
| Treacher, DF | 1 |
| Douglas, A | 1 |
| Jones, A | 1 |
| Bateman, NT | 1 |
| Bradley, RD | 1 |
| Samuel, JL | 1 |
| McGonigle, RJ | 1 |
| Brookins, J | 1 |
| Pegram, BL | 1 |
| Fisher, JW | 1 |
| Mårtensson, L | 1 |
| Davoust, N | 1 |
| Anno, T | 1 |
| Kodama, I | 1 |
| Shibata, S | 1 |
| Toyama, J | 1 |
| Yamada, K | 1 |
| Schwertschlag, U | 1 |
| Wilson, P | 1 |
| Kano, T | 1 |
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| Smallbone, BW | 1 |
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| Noulty, EJ | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of High Altitude on 5' Adenosine Monophosphate-activated Protein Kinase (AMPK) Activation and Peroxisome Proliferator-activated Receptor Gamma (PPARγ) Regulation[NCT02391519] | 84 participants (Anticipated) | Observational | 2016-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for verapamil and Anoxemia
| Article | Year |
|---|---|
[Hypoxic pulmonary hypertension: modern views on pathogenesis and options for rational pharmacological correction].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels; Humans; Hypertension, Pulmonary | 2012 |
[Recent advances and future perspectives in the medical treatment of cardiopathies in children].
Topics: Child; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Failure; Humans; Hypoxia; Indomet | 1984 |
Therapeutic application of calcium-channel antagonists for pulmonary hypertension.
Topics: Animals; Calcium Channel Blockers; Cattle; Diltiazem; Hemodynamics; Humans; Hypertension, Pulmonary; | 1985 |
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide; | 1974 |
[Modern treatment of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bradycardia; Cell Membrane Permeability; Digitali | 1971 |
3 trials available for verapamil and Anoxemia
| Article | Year |
|---|---|
Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m).
Topics: Adult; Altitude; Area Under Curve; Calcium Channel Blockers; Cross-Over Studies; Cytochrome P-450 CY | 2005 |
Effect of verapamil on ventilatory and circulatory responses to hypoxia and hypercapnia in normal subjects.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium; Carotid Body; Double-Blind Method; Electrocard | 1992 |
Ventilatory response to sustained hypoxia: effect of methysergide and verapamil.
Topics: Adult; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypo | 1989 |
112 other studies available for verapamil and Anoxemia
| Article | Year |
|---|---|
Hypoxia-Protective Azaphilone Adducts from Peyronellaea glomerata.
Topics: Apoptosis; Ascomycota; Benzopyrans; Cells, Cultured; Crystallography, X-Ray; Endophytes; Human Umbil | 2018 |
Role of TRP channels and NCX in mediating hypoxia-induced [Ca(2+)](i) elevation in PC12 cells.
Topics: Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Gene | 2008 |
Efficacy of oxygen inhalation in sumatriptan refractory "high altitude" cluster headache attacks.
Topics: Adult; Altitude Sickness; Atmospheric Pressure; Calcium Channel Blockers; Cluster Headache; Drug Res | 2009 |
Role of KATP and L-type Ca2+ channel activities in regulation of ovine uterine vascular contractility: effect of pregnancy and chronic hypoxia.
Topics: Adenosine Triphosphate; Altitude; Animals; Arteries; Calcium Channels, L-Type; Disease Models, Anima | 2010 |
Hypoxic rise in cytosolic calcium and renal proximal tubule injury mediated by a nickel-sensitive pathway.
Topics: Animals; Calcium; Calcium Channel Blockers; Cytoplasm; Female; GABA Modulators; Humans; Hypoxia; Kid | 2004 |
Hypoxia-induced cardiac hypertrophy in rabbits treated with verapamil and nifedipine.
Topics: Animals; Cardiomegaly; Eating; Hypoxia; Nifedipine; Organ Size; Rabbits; Verapamil | 1983 |
On the role of cyclic nucleotides in the regulation of cardiac contractility and glycolysis during hypoxia.
Topics: Animals; Cyclic AMP; Cyclic GMP; Glycolysis; Hypoxia; Lactates; Lactic Acid; Male; Myocardial Contra | 1981 |
[Verapamil in rats exposed to intermittent altitude hypoxia. Its effect on pulmonary hypertension, right ventricular hypertrophy and myocardial necroses (author's transl)].
Topics: Animals; Cardiomegaly; Hypertension, Pulmonary; Hypoxia; Male; Myocardium; Necrosis; Rats; Rats, Inb | 1981 |
Effect of verapamil on pulmonary hypertension and right ventricular hypertrophy induced in rats by intermittent high altitude hypoxia.
Topics: Altitude Sickness; Animals; Body Weight; Cardiomegaly; Hematocrit; Hemodynamics; Hemoglobins; Hypert | 1981 |
Mechanisms of hypoxia-induced decrease of load dependence of relaxation in cat papillary muscle.
Topics: Animals; Biomechanical Phenomena; Calcium; Cats; Hypoxia; In Vitro Techniques; Myocardial Contractio | 1984 |
Pulmonary vascular response to digoxin in newborn lambs.
Topics: Animals; Animals, Newborn; Digoxin; Hemodynamics; Hypoxia; Oxygen Consumption; Pulmonary Circulation | 1984 |
The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet.
Topics: Animals; Animals, Newborn; Cardiac Output; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary W | 1984 |
Comparative effects of nifedipine, verapamil, and diltiazem on experimental pulmonary hypertension.
Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Dinoprost; Dogs; Dose-Response Rel | 1983 |
Effects of verapamil on pulmonary haemodynamics during hypoxaemia, at rest, and during exercise in patients with chronic obstructive pulmonary disease.
Topics: Aged; Blood Pressure; Hemodynamics; Humans; Hypoxia; Lung Diseases, Obstructive; Middle Aged; Physic | 1983 |
Oxygen transport during hemodilution in normoxic and hypoxic dogs treated with verapamil.
Topics: Animals; Biological Transport; Dogs; Hematocrit; Hemodilution; Hemodynamics; Hypoxia; Lactates; Oxyg | 1983 |
Mechanism of protection by verapamil and nifedipine from anoxic injury in isolated cardiac myocytes.
Topics: Animals; Biomechanical Phenomena; Calcium; Hypoxia; Myocardial Contraction; Myocardium; Nifedipine; | 1984 |
Flunarizine and verapamil: effects on central nervous system and peripheral consequences of cytotoxic hypoxia in rats.
Topics: Animals; Calcium Channel Blockers; Cinnarizine; Flunarizine; Hyperventilation; Hypoxia; Male; Pipera | 1984 |
Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists.
Topics: Adenine Nucleotides; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Corona | 1984 |
Contribution of adenosine to the regulation of cerebral blood flow: the role of calcium ions in the adenosine-induced cerebrocortical vasodilatation.
Topics: Adenosine; Animals; Calcium; Calcium Channel Blockers; Cats; Cerebral Cortex; Cerebrovascular Circul | 1984 |
Action of the Na+ ionophore monensin on vascular smooth muscle of guinea-pig aorta.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Furans; Glucose; Guinea Pigs; Hypoxia; In Vitro Te | 1984 |
Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists.
Topics: Animals; Dimethyl Sulfoxide; Hydralazine; Hypertension, Pulmonary; Hypoxia; Male; Nifedipine; Pulmon | 1984 |
The effect of extracellular calcium concentration and Ca-antagonist drugs on enzyme release and lactate production by anoxic heart cell cultures.
Topics: Animals; Calcium; Cells, Cultured; Glucose; Heart; Hypoxia; L-Lactate Dehydrogenase; Lactates; Manni | 1980 |
Effect of the organic calcium antagonist D-600 on cerebrocortical vascular and redox responses evoked by adenosine, anoxia, and epilepsy.
Topics: Adenosine; Animals; Blood Volume; Cats; Cerebral Cortex; Cerebrovascular Circulation; Electrocardiog | 1983 |
Regulation of cardiac contractility and glycolysis by cyclic nucleotides during hypoxia.
Topics: Animals; Calcium; Glycolysis; Hypoxia; Male; Myocardial Contraction; Myocardium; Nitroprusside; Nore | 1983 |
The effects of inhibition of oxidative phosphorylation and glycolysis on contractility and high-energy phosphate content in cultured chick heart cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Cyanides; Glycolysis; Heart Ventricl | 1983 |
Failure of verapamil to increase survival time in hypoxic mice.
Topics: Animals; Hypoxia; Male; Mice; Oxygen; Verapamil | 1982 |
Peculiarities of AV nodal conduction and the role of slow Na current.
Topics: Action Potentials; Animals; Atrioventricular Node; Calcium; Heart Conduction System; Hypoxia; In Vit | 1981 |
Inhibitory effect of anoxia on reperfusion- and digitalis-induced ventricular tachyarrhythmias.
Topics: Animals; Coronary Disease; Guinea Pigs; Heart Ventricles; Hypoxia; Male; Medigoxin; Oxygen; Perfusio | 1981 |
Different electrophysiological responses of canine endocardium and epicardium to combined hyperkalemia, hypoxia, and acidosis.
Topics: Acidosis; Action Potentials; Animals; Dogs; Electrophysiology; Endocardium; Hyperkalemia; Hypoxia; M | 1980 |
Inhibitors of oxidative ATP production cause transient vasoconstriction and block subsequent pressor responses in rat lungs.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antimycin A; Azides; Blood Pressure; Calcium; Dinit | 1981 |
Acute hypoxia causes membrane depolarization and calcium influx in fetal pulmonary artery smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries.
Topics: Aged; Animals; Benzopyrans; Calcium; Calcium Channels; Cromakalim; Glyburide; Humans; Hypoxia; In Vi | 1995 |
Protection from hypoxemic renal dysfunction by verapamil and manganese in the rabbit.
Topics: Animals; Calcium; Hypoxia; Kidney; Kidney Diseases; Male; Manganese; Rabbits; Verapamil | 1995 |
Effects of catecholamines on the residual sodium channel dependent slow conduction in guinea pig ventricular muscles under normoxia and hypoxia.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channels; Catecholamines; Dose-Response Re | 1995 |
Calcium modulation and cell injury in isolated rat proximal tubules.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Membrane Permeability; Cell Survival; Hypoxia; In Vit | 1993 |
Noncardiogenic pulmonary edema complicating massive verapamil overdose.
Topics: Adult; Drug Overdose; Dyspnea; Female; Humans; Hypotension; Hypoxia; Pulmonary Edema; Verapamil | 1994 |
Modulation of vasodilatation to levcromakalim by hypoxia and EDRF in the rabbit isolated ear: a comparison with pinacidil, sodium nitroprusside and verapamil.
Topics: Acetylcholine; Animals; Arginine; Benzopyrans; Cromakalim; Ear, External; Guanidines; Hypoxia; In Vi | 1993 |
Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes.
Topics: Acute Disease; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cu | 1993 |
Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Coronary Vasospasm; Dog | 1996 |
[Effect of calcium and its antagonists on hemodynamics and respiration].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Calcium Chloride; Cardiac Output; Cats; Cerebrova | 1996 |
The energetics of the quiescent heart muscle: high potassium cardioplegic solution and the influence of calcium and hypoxia on the rat heart.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cardioplegic Solutions; Ener | 1997 |
Effects of verapamil and ryanodine on activity of the embryonic chick heart during anoxia and reoxygenation.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Chick Embryo; Contr | 1998 |
Membrane potential-dependent and -independent vasodilation in small pulmonary arteries from chronically hypoxic rats.
Topics: Animals; Body Weight; Cromakalim; Dinoprost; Dose-Response Relationship, Drug; Heart Ventricles; Hem | 1998 |
Effects of hypoxia on pulmonary vascular contractility.
Topics: Animals; Blood Vessels; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Hypo | 1998 |
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Diltiazem; | 2000 |
Halothane differentially decreases 5-hydroxytryptamine-induced contractions in normal and chronic hypoxic rat pulmonary arteries.
Topics: Anesthetics, Inhalation; Animals; Cadmium; Calcium Channel Blockers; Chronic Disease; Halothane; Hyp | 2001 |
The effect of beta-adrenoceptor and Ca2+ antagonist drugs on the hypoxia-induced increased in resting tension.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Depression, Chemical; Guinea Pigs; Heart Rate; Hypert | 1978 |
The effect of Ca ion antagonist verapamil on ouabain inhibition of renal sodium reabsorption. Studies in the isolated perfused rat kidney.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Biological Transport; Calcium; Glomerular F | 1976 |
[Creatine phosphokinase release from perfused cardiac muscle under hypoxic conditions. Effect of propranolol, verapamil, reserpine and deslanoside].
Topics: Animals; Creatine Kinase; Deslanoside; Hypoxia; Lanatosides; Male; Myocardium; Propranolol; Rabbits; | 1979 |
Pharmacological protection of mitochondrial function in hypoxic heart muscle: Effect of verapamil, propranolol, and methylprednisolone.
Topics: Animals; Calcium; Hypoxia; In Vitro Techniques; Male; Methylprednisolone; Mitochondria, Heart; Oxida | 1978 |
Pulmonary vascular effects of verapamil.
Topics: Altitude; Animals; Blood Pressure; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Circulation; Ra | 1978 |
Reduction of bovine pulmonary hypertension by normoxia, verapamil and hexoprenaline.
Topics: Airway Resistance; Animals; Blood Pressure; Calcium; Cattle; Hexoprenaline; Hypertension, Pulmonary; | 1977 |
Angiotensin, hypoxia, verapamil and pulmonary vessels [proceedings].
Topics: Angiotensin II; Animals; Cats; Dogs; Ferrets; Hypoxia; In Vitro Techniques; Pulmonary Circulation; R | 1977 |
A protective effect of verapamil on hypoxic heart muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Creatine Kinase; Heart; Hypoxia; Male; Mitochondrial Swell | 1976 |
[The effect of increased extracellular calcium concentration on the hypoxic and pharmacologic hyperemia of skeletal muscle].
Topics: Adenosine; Animals; Calcium; Dogs; Hyperemia; Hypoxia; Muscles; Nifedipine; Regional Blood Flow; Sti | 1975 |
Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs.
Topics: Angiotensin II; Animals; Calcium; Hypoxia; Male; Meclofenamic Acid; Proadifen; Prostaglandins; Prost | 1976 |
Attenuation of hypoxic pulmonary vasoconstriction by verapamil in intact dogs.
Topics: Animals; Calcium; Dogs; Hypoxia; Lung; Muscle, Smooth; Prostaglandins F; Time Factors; Vascular Resi | 1976 |
Effects of anoxia and glucose depletion on isolated veins of the dog.
Topics: Acetylcholine; Animals; Dogs; Glucose; Hypoxia; In Vitro Techniques; Mesenteric Veins; Muscle Contra | 1976 |
[Effects of calcium blockers on the performance of left and right ventricles during acute hypoxia].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Hemodynamics; Hypoxia; Male; Nif | 1992 |
Hypoxia-induced von Willebrand factor release is blocked by verapamil.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Humans; Hypoxia; Verapamil; von Willebrand Facto | 1992 |
Modification by hypoxia, hyperkalaemia and acidosis of the cardiac electrophysiological effects of a range of antiarrhythmic drugs.
Topics: Acidosis; Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Ele | 1992 |
Direct amphotericin B-mediated tubular toxicity: assessments of selected cytoprotective agents.
Topics: Adenosine Triphosphate; Amphotericin B; Animals; Calcium; Cholesterol Esters; Deoxycholic Acid; Dose | 1992 |
[The effects of calcium antagonists on ventilation-perfusion mismatching in the canine lung].
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Hypoxia; Models, Biological; Nifedipine; Oxygen; | 1992 |
Diverse effects of calcium channel blockers on skeletal muscle glucose transport.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Calcium Channel Blockers; Diltiazem; Dose-Response | 1992 |
Pharmacological evidence for the role of mediators in hypoxia-induced vasoconstriction in sheep isolated intrapulmonary artery rings.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channels; Enzyme Inhibitors; Flurbiprofen; Hypoxia; I | 1991 |
[Verapamil and nifedipine limit hemodynamic changes in pulmonary circulation in rats with hypoxia].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Disease Models, Animal; Hype | 1991 |
Verapamil prevents cerebral acidosis during moderate hypoxia and hypotension.
Topics: Acidosis; Animals; Brain; Glucose; Hypotension; Hypoxia; Male; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Effects of hypoxia and reoxygenation on the conversion of xanthine dehydrogenase to oxidase in Chinese hamster V79 cells.
Topics: Allopurinol; Animals; Calcium; Cell Line; Cell Membrane; Cricetinae; Cricetulus; Glucose; Hypoxia; L | 1991 |
Contrasting effects of hypoxia on tension in rat pulmonary and mesenteric arteries.
Topics: Animals; Benzopyrans; Cromakalim; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Ma | 1990 |
[Prevention of hypoxic pulmonary hypertension with "qi-xue" injection].
Topics: Animals; Drugs, Chinese Herbal; Hypertension, Pulmonary; Hypoxia; Injections; Male; Panax; Plants, M | 1990 |
Triggered activity induced by combined mild hypoxia and acidosis in guinea-pig Purkinje fibers.
Topics: Acidosis; Animals; Arrhythmias, Cardiac; Calcium; Female; Guinea Pigs; Heart Conduction System; Hypo | 1986 |
Relationship of myocardial metabolism and coronary flow: dependence on extracellular calcium.
Topics: Adenosine Triphosphate; Amobarbital; Animals; Calcium; Calcium Channel Blockers; Coronary Circulatio | 1987 |
[Enzyme activity of cardiac glycogen metabolism: study of an in situ hypoxia protocol in the rat].
Topics: Animals; Atenolol; Calcium; Cyclic AMP; Enzyme Activation; Female; Glycogen; Glycogen Synthase; Hear | 1989 |
Effects of chronic hypoxia and verapamil on cAMP content in tissues and blood plasma.
Topics: Animals; Carotid Arteries; Cyclic AMP; Heart; Hypoxia; Lung; Male; Muscle, Smooth, Vascular; Myocard | 1989 |
Verapamil attenuates ATP depletion during hypoxia: 31P NMR studies of the isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Energy Metabolism; Heart; Hemodynamics; Hydro | 1989 |
Effects of dextrose, verapamil and magnesium during hypoxia in myocardial tissue.
Topics: Action Potentials; Anaerobiosis; Animals; Calcium; Dogs; Female; Glucose; Heart; Hypoxia; Magnesium; | 1989 |
Serotonin uptake and configurational change of bovine pulmonary artery smooth muscle cells in culture.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; Hypoxia; Imipramine; Microscopy, Phase-Contrast; Mu | 1989 |
Interaction of verapamil and halogenated inhalation anesthetics on hypoxic pulmonary vasoconstriction.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Calcium Chloride; Drug Interactions; Halothane; Hyp | 1989 |
Effects of hypoxia on the pharmacological responsiveness of isolated coronary artery rings from the sheep.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Hypox | 1989 |
Effects of manganese chloride, verapamil, and hypoxia on the rate-dependent increase in internal longitudinal resistance of rabbit myocardium.
Topics: Animals; Chlorides; Electric Conductivity; Electric Stimulation; Hypoxia; In Vitro Techniques; Manga | 1989 |
Effect of emopamil on cerebrocortical microcirculation during hypoxia and reactive hyperemia and on [K+]e, pH, pO2 changes during and after N2 anoxia.
Topics: Animals; Calcium Channel Blockers; Cats; Cerebral Cortex; Hydrogen-Ion Concentration; Hyperemia; Hyp | 1989 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Is | 1986 |
Verapamil depresses the synthesis of lipoxygenase products by hypoxic cardiac rat fibroblasts in culture.
Topics: Anaerobiosis; Animals; Cells, Cultured; Fibroblasts; Hypoxia; Kinetics; Lipoxygenase Inhibitors; Myo | 1986 |
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dog | 1986 |
Verapamil enhances brain function tolerance against severe hypoxia without enhancing cerebral blood flow in the rat.
Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Electrocardiography; El | 1987 |
Effect of verapamil on polycythaemia secondary to hypoxia in rats.
Topics: Animals; Carbon Dioxide; Erythrocyte Volume; Hematocrit; Hemoglobins; Hypoxia; Male; Oxygen; Polycyt | 1987 |
Calcium and hypoxic injury in the renal medulla of the perfused rat kidney.
Topics: Amino Acids; Animals; Calcium-Binding Proteins; Glomerular Filtration Rate; Hypercalcemia; Hypoxia; | 1988 |
Diltiazem and verapamil reduce the loss of adenine nucleotide metabolites from hypoxic hearts.
Topics: Adenine Nucleotides; Adenosine; Animals; Body Water; Calcium; Creatine Kinase; Diltiazem; Female; He | 1988 |
[Hemodynamic effect of a single intravenous dose of verapamil in patients with hypoxemic pulmonary hypertension].
Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Infusions, Intravenous; | 1988 |
Slow channel inhibitor effects on brain function: tolerance to severe hypoxia in the rat.
Topics: Animals; Bencyclane; Bepridil; Brain; Calcium Channel Blockers; Cinnarizine; Diltiazem; Electroencep | 1988 |
The acute haemodynamic effects of intravenous verapamil in patients with chronic obstructive airways disease.
Topics: Acute Disease; Cardiac Output; Female; Hemodynamics; Humans; Hypoxia; Infusions, Intravenous; Lung D | 1987 |
Calcium antagonists stimulate prostaglandin synthesis by cultured rat cardiac myocytes and prevent the effects of hypoxia.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cells, Cultured; Cobalt; Diltiazem; Dinoprostone; Epopr | 1986 |
Enhanced erythropoietin production by calcium entry blockers in rats exposed to hypoxia.
Topics: Animals; Biological Assay; Blood Pressure; Calcium Channel Blockers; Erythropoietin; Female; Hypoxia | 1987 |
Effects of indomethacin or verapamil on dialysis induced leucopenia and hypoxia in the unstressed sheep.
Topics: Animals; Extracorporeal Circulation; Hypoxia; Indomethacin; Leukopenia; Renal Dialysis; Sheep; Verap | 1987 |
Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia.
Topics: Animals; Atrioventricular Node; Calcium; Calcium Channel Blockers; Calmodulin; Chlorpromazine; Heart | 1986 |
Beneficial effects of calcium channel blockers and calmodulin binding drugs on in vitro renal cell anoxia.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cell Survival; Cells, Cultured; Hypoxia; Isomerism; N | 1986 |
External pH dependency of delayed afterdepolarization in rabbit myocardium.
Topics: Animals; Doxorubicin; Electrophysiology; Female; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techn | 1986 |
Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Complement Activation; Female; Hypertension, Pulmonary; Hypox | 1986 |
Verapamil improves defective duodenal calcium absorption in experimental chronic renal failure.
Topics: Aminoquinolines; Animals; Calcium; Duodenum; Hypoxia; Intestinal Absorption; Kidney Cortex; Kidney F | 1986 |
Maps of optical action potentials and NADH fluorescence in intact working hearts.
Topics: Action Potentials; Algorithms; Animals; Coronary Vessels; Fluorescence; Guinea Pigs; Heart; Heart Ra | 1987 |
TEA prevents the decline of the duration of the action potential in hypoxic cardiac muscle.
Topics: Action Potentials; Animals; Calcimycin; Calcium Chloride; Guinea Pigs; Heart; Hypoxia; In Vitro Tech | 1985 |
Effect of verapamil on ventilation and chemical control of breathing in anesthetized rats.
Topics: Anesthesia; Animals; Carbon Dioxide; Hypoxia; Male; Rats; Respiration; Vagotomy; Verapamil | 1985 |
Myocardial reoxygenation damage: can it be circumvented?
Topics: Animals; Calcium; Cats; Diltiazem; Heart; Hypoxia; In Vitro Techniques; Lidoflazine; Myocardial Cont | 1985 |
The effects of lidoflazine and flunarizine on cerebral reactive hyperemia.
Topics: Animals; Blood Gas Analysis; Cerebrovascular Circulation; Cinnarizine; Extracorporeal Circulation; F | 1985 |
Potentiation by calcium channel blockade of hypoxic myocardial depression in the neonate.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Diastole; Hypoxia; Myocardial Contraction; Prac | 1985 |
[Differentiation between real and apparent beta receptor blockade in the heart].
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Electrocardiography; Glycogen; Heart; Heart Rate; H | 1974 |
[Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions].
Topics: Animals; Coronary Circulation; Dipyridamole; Female; Heart; Hypoxia; Male; Myocardium; Nitroglycerin | 1974 |
[Effect of Verapamil on the metabolism of myocardium].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Asphyxia; Blood Glucos | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Control of myocardial metabolism by verapamil. Sites of action and therapeutic effects].
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Cell Membrane Permeability; Guinea Pigs; Heart; Heart Cond | 1970 |
[On the protective effect of iproveratil in myocardial diseases due to hypertension in animal experiment].
Topics: Animals; Anti-Arrhythmia Agents; Electrocardiography; Heart Diseases; Hypertension, Renal; Hypoxia; | 1967 |