Page last updated: 2024-10-24

verapamil and Angiospasm, Intracranial

verapamil has been researched along with Angiospasm, Intracranial in 45 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"High-dose IA verapamil treatment is well-tolerated in the high-risk aneurysmal subarachnoid hemorrhage population that experience severe, symptomatic CVS with good functional outcomes at follow-up."8.02The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Esplin, N; Gigliotti, MJ; Mao, G; Sexton, K, 2021)
"We studied 11 patients with poor-grade aneurysmal subarachnoid hemorrhages who underwent multimodality brain monitoring and angiography with infusion of high-dose intra-arterial verapamil (≥15 mg total dose)."7.77High-dose intra-arterial verapamil for the treatment of cerebral vasospasm after subarachnoid hemorrhage: prolonged effects on hemodynamic parameters and brain metabolism. ( Badjatia, N; Claassen, J; Connolly, ES; Fernandez, L; Helbok, R; Kurtz, P; Lavine, S; Lee, K; Mayer, SA; Meyers, P; Schmidt, M; Stuart, RM, 2011)
" Intra-arterial verapamil was started; during this treatment, the patient developed right-sided focal motor seizures."7.74Intra-arterial verapamil-induced seizures: case report and review of the literature. ( Nwagwu, CI; Westhout, FD, 2007)
"The only pharmacologic prophylaxis for cerebral vasospasm after subarachnoid hemorrhage is oral nimodipine."5.46Verapamil eluting stents as a possible treatment for vasospasm after subarachnoid hemorrhage. ( Bhambri, P; Mitha, AP; Sarvi, A; Sundararaj, U; Wong, JH, 2017)
"According to angiorraphy cerebral vasospasm in acute rupture of an aneurysm is detected in 50-70% of cases, and the risk of ischemia on it's background is 19-46%."5.39[Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: case report]. ( Éliava, ShSh; Iakovlev, SB; Lubnin, AIu; Mikeladze, KG; Shekhtman, OD; Tabasaranskiĭ, TF, 2013)
"The first results of intracisternal administration of verapamil for the prevention and treatment of cerebral vasospasm (CVS) in patients in the acute period of subarachnoid hemorrhage (SAH) after microsurgical clipping of cerebral aneurysms are presented."5.30[Intracisternal administration of verapamil for the prevention and treatment of vasospasm in patients after microsurgical treatment of cerebral aneurysms in the acute period of hemorrhage]. ( Baranich, AI; Belousova, OB; Eliava, SS; Gorozhanin, VA; Kheyreddin, AS; Konovalov, AN; Kurdyumova, NV; Mikeladze, KG; Okishev, DN; Pilipenko, YV; Savin, IA; Shekhtman, OD; Spiru, AM; Tabasaransky, TF; Varyukhina, MD; Vinogradov, EV, 2019)
"High-dose IA verapamil treatment is well-tolerated in the high-risk aneurysmal subarachnoid hemorrhage population that experience severe, symptomatic CVS with good functional outcomes at follow-up."4.02The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Esplin, N; Gigliotti, MJ; Mao, G; Sexton, K, 2021)
"We outline the clinical presentation of a 56-year-old female with spontaneous subarachnoid hemorrhage with intraventricular extension in a coma from a petroclival meningioma taking escitalopram for depression and high-dose estrogen replacement therapy for menopause."3.96Intracranial Hemorrhage from Meningioma: 2 Novel Risk Factors. ( Patel, NJ; Penn, D; Pressman, E, 2020)
"Using PubMed and Google Scholar, we performed a search of the English language literature with several combinations of the keywords "intra-arterial", "calcium channel blockers", "reversible cerebral vasoconstriction syndrome", "RCVS", "nimodipine", "verapamil", "milrinone", and "nicardipine" to identify studies in which RCVS was treated with IA calcium channel blockers."3.88Chemical angioplasty for medically refractory reversible cerebral vasoconstriction syndrome ( Al-Mufti, F; Alchaki, A; Dodson, V; El-Ghanem, M; Gupta, G; Hidalgo, A; Nuoman, R; Roychowdhury, S; Sutherland, A; Thabet, A; Wajswol, E, 2018)
"We studied 11 patients with poor-grade aneurysmal subarachnoid hemorrhages who underwent multimodality brain monitoring and angiography with infusion of high-dose intra-arterial verapamil (≥15 mg total dose)."3.77High-dose intra-arterial verapamil for the treatment of cerebral vasospasm after subarachnoid hemorrhage: prolonged effects on hemodynamic parameters and brain metabolism. ( Badjatia, N; Claassen, J; Connolly, ES; Fernandez, L; Helbok, R; Kurtz, P; Lavine, S; Lee, K; Mayer, SA; Meyers, P; Schmidt, M; Stuart, RM, 2011)
" Data were retrospectively collected, including age, sex, Hunt and Hess grade, Fisher grade, aneurysm location, aneurysm treatment, day of the onset of vasospasm, intracranial pressure, mean arterial pressures, intraarterial treatment of vasospasm, dosages and times of verapamil infusion, presence of a new ischemic area on CT scan, modified Rankin scale score at discharge and at the last clinical follow-up, and discharge status."3.76Ultrahigh-dose intraarterial infusion of verapamil through an indwelling microcatheter for medically refractory severe vasospasm: initial experience. Clinical article. ( Albanese, E; Mericle, RA; Quiroga, M; Russo, A; Ulm, AJ; Willis, RN, 2010)
" After receiving a nonselective slow infusion of verapamil, the patient developed an episode of extreme hypertension."3.75Near-complete resolution of angiographic cerebral vasospasm after extreme elevation of mean arterial pressure: case report. ( Dacey, RG; Derdeyn, CP; Diringer, MN; Moran, CJ; Ray, WZ; Zipfel, GJ, 2009)
" Intra-arterial verapamil was started; during this treatment, the patient developed right-sided focal motor seizures."3.74Intra-arterial verapamil-induced seizures: case report and review of the literature. ( Nwagwu, CI; Westhout, FD, 2007)
"We retrospectively reviewed the procedure reports, anesthesia records, clinical charts, and brain images of 29 patients who received intraarterially administered verapamil in 34 procedures for the treatment of vasospasm after subarachnoid hemorrhage from July 1998 to June 2000."3.71Intraarterially administered verapamil as adjunct therapy for cerebral vasospasm: safety and 2-year experience. ( Aagaard, BD; Berman, MF; Duong, H; Feng, L; Fitzsimmons, BF; Lin, E; Pile-Spellman, J; Young, WL, 2002)
" The most common oral verapamil dosing regimen was controlled release 120 mg once daily."3.01Verapamil in the treatment of reversible cerebral vasoconstriction syndrome: A systematic review. ( Bacchi, S; Bagster, M; Collins, L; Goh, R; Gupta, A; Kleinig, O; Kleinig, T; Kovoor, J; Lam, L; Proudman, W; Schultz, D; Zhang, R, 2023)
"Patients with cerebral vasospasm caused by aneurysmal subarachnoid hemorrhage (aSAH) are often treated with intra-arterial (IA) vasodilator infusion."1.62Use of single versus multiple vasodilator agents in the treatment of cerebral vasospasm: is more better than less? ( Bulsara, K; Chen, PR; Day, AL; Erkmen, K; Kim, DH; Lopez-Rivera, V; Oni-Orisan, AO; Sanzgiri, A; Sheriff, FG; Sheth, S; Vahidy, FS, 2021)
"The age is from 8 to 77 years."1.56Intra-arterial Administration of Verapamil for the Prevention and Treatment of Cerebral Angiospasm. ( Ageev, IS; Belousova, OB; Eliava, SS; Kaftanov, AN; Konovalov, AN; Kurdyumova, NV; Mikeladze, KG; Okishev, DN; Okisheva, EA; Pilipenko, YV; Shekhtman, OD; Tabasaransky, TF; Yakovlev, SB, 2020)
"Verapamil was more frequently used for clinical vasospasm in UH patients, at 0."1.56Discrepancy in Neurologic Outcomes Following Aneurysmal Subarachnoid Hemorrhage as a Function of Socioeconomic Class. ( Amar, A; Bakhsheshian, J; Chartrain, A; Giannotta, SL; Jackanich, A; Mack, W; Mert, M; Ravina, K; Rennert, RC; Russin, JJ; Shahrestani, S; Strickland, BA, 2020)
" Quantitative thresholds and analysis based on DSA perfusion may assist with real-time dosage estimation and help predict response to treatment, however future prospective analysis is required for validation."1.56Computational methods for visualizing and measuring verapamil efficacy for cerebral vasospasm. ( Abumoussa, A; Flores, A; Ho, J; Lee, YZ; Niethammer, M; Sasaki-Adams, D, 2020)
"The only pharmacologic prophylaxis for cerebral vasospasm after subarachnoid hemorrhage is oral nimodipine."1.46Verapamil eluting stents as a possible treatment for vasospasm after subarachnoid hemorrhage. ( Bhambri, P; Mitha, AP; Sarvi, A; Sundararaj, U; Wong, JH, 2017)
"Cerebral vasospasm is a devastating complication after subarachnoid hemorrhage."1.43Initial clinical experience with near-infrared spectroscopy in assessing cerebral tissue oxygen saturation in cerebral vasospasm before and after intra-arterial verapamil injection. ( Flexman, AM; Higashida, RT; Meng, L; Settecase, F; Xiao, J; Yu, Z, 2016)
"Verapamil was the most common first-line therapy in the United States, whereas nimodipine was most popular in non-U."1.42Results of an International Survey on the Investigation and Endovascular Management of Cerebral Vasospasm and Delayed Cerebral Ischemia. ( Bulsara, KR; Chen, PR; Coulthard, A; Goddard, AJ; Hollingworth, M; Söderman, M, 2015)
"However, posterior reversible encephalopathy syndrome (PRES) is a hyperperfusion syndrome reported as a rare complication of IH that may confound this picture."1.42Posterior reversible encephalopathy syndrome with thalamic involvement during vasopressor treatment of vertebrobasilar vasospasm after subarachnoid hemorrhage. ( Dhar, R; Madaelil, TP, 2015)
"According to angiorraphy cerebral vasospasm in acute rupture of an aneurysm is detected in 50-70% of cases, and the risk of ischemia on it's background is 19-46%."1.39[Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: case report]. ( Éliava, ShSh; Iakovlev, SB; Lubnin, AIu; Mikeladze, KG; Shekhtman, OD; Tabasaranskiĭ, TF, 2013)
"The dose-response studies revealed that intracarotid administration of nicardipine, compared with verapamil, was more effective in augmenting cerebral blood flow."1.34Augmentation of cerebral blood flow and reversal of endothelin-1-induced vasospasm: a comparison of intracarotid nicardipine and verapamil. ( Etu, JJ; Joshi, S; Lavine, SD; Meyers, PM; Wang, M, 2007)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (24.44)29.6817
2010's25 (55.56)24.3611
2020's9 (20.00)2.80

Authors

AuthorsStudies
Collins, L1
Lam, L1
Kleinig, O1
Proudman, W1
Zhang, R1
Bagster, M1
Kovoor, J1
Gupta, A1
Goh, R1
Bacchi, S1
Schultz, D1
Kleinig, T1
Mikeladze, KG3
Okishev, DN2
Belousova, OB2
Konovalov, AN2
Pilipenko, YV2
Ageev, IS1
Kaftanov, AN1
Shekhtman, OD3
Kurdyumova, NV2
Tabasaransky, TF2
Okisheva, EA1
Eliava, SS2
Yakovlev, SB1
Varyukhina, MD1
Savin, IA1
Kheyreddin, AS1
Gorozhanin, VA1
Spiru, AM1
Baranich, AI1
Vinogradov, EV1
Pressman, E1
Penn, D1
Patel, NJ1
Ospel, JM1
Wright, CH1
Jung, R1
Vidal, LLM1
Manjila, S1
Singh, G1
Heck, DV1
Ray, A1
Blackham, KA1
Liu, X1
Vitt, JR1
Hetts, SW2
Gudelunas, K1
Ho, N1
Ko, N1
Hu, X1
Strickland, BA1
Mert, M1
Ravina, K1
Chartrain, A1
Rennert, RC1
Bakhsheshian, J1
Shahrestani, S1
Jackanich, A1
Amar, A1
Mack, W1
Russin, JJ1
Giannotta, SL1
Chen, PR2
Bulsara, K1
Lopez-Rivera, V1
Sheriff, FG1
Sanzgiri, A1
Sheth, S1
Oni-Orisan, AO1
Vahidy, FS1
Erkmen, K1
Kim, DH1
Day, AL1
Abumoussa, A1
Flores, A1
Ho, J1
Niethammer, M1
Sasaki-Adams, D1
Lee, YZ1
Mao, G1
Gigliotti, MJ1
Esplin, N1
Sexton, K1
Al-Mufti, F2
Dodson, V1
Wajswol, E1
El-Ghanem, M1
Alchaki, A1
Nuoman, R1
Thabet, A1
Sutherland, A1
Roychowdhury, S1
Hidalgo, A1
Gupta, G1
Folzenlogen, Z1
Seinfeld, J1
Kubes, S1
Kumpe, D1
Case, D1
Roark, C1
Akkaya, E1
Evran, Ş1
Çalış, F1
Çevik, S1
Hanımoğlu, H1
Seyithanoğlu, MH1
Katar, S1
Karataş, E1
Koçyiğit, A1
Sağlam, MY1
Hatiboğlu, MA1
Kaynar, MY1
Éliava, ShSh1
Lubnin, AIu1
Tabasaranskiĭ, TF1
Iakovlev, SB1
Chia, NH1
Kleinig, TJ1
Komatsu, T1
Kimura, T1
Yagishita, A1
Takahashi, K1
Koide, R1
Mortimer, AM1
Steinfort, B1
Faulder, K1
Bradford, C1
Finfer, S1
Assaad, N1
Harrington, T1
Hollingworth, M1
Goddard, AJ1
Coulthard, A1
Söderman, M1
Bulsara, KR1
Chen, SH1
Grandhi, R1
Deibert, CP1
Jovin, TG1
Gardner, PA1
Ducruet, AF1
Madaelil, TP1
Dhar, R1
Maniskas, ME1
Roberts, JM1
Aron, I1
Fraser, JF1
Bix, GJ1
Meng, L1
Settecase, F1
Xiao, J1
Yu, Z1
Flexman, AM2
Higashida, RT2
Amuluru, K1
Singh, IP1
Frohman, LP1
Gandhi, CD1
Liu, JK1
Bhambri, P1
Sarvi, A1
Wong, JH1
Sundararaj, U1
Mitha, AP1
Kulkarni, M1
Chauhan, V1
Shetty, S1
Perdices, M1
Herkes, G1
Bouchard, M1
Verreault, S1
Gariépy, JL1
Dupré, N1
Shahlaie, K1
Boggan, JE1
Latchaw, RE1
Ji, C1
Muizelaar, JP1
Lee, DJ1
Moftakhar, P1
Glenn, TC1
Vespa, PM1
Martin, NA1
Ray, WZ1
Moran, CJ3
Derdeyn, CP3
Diringer, MN1
Dacey, RG1
Zipfel, GJ1
Albanese, E1
Russo, A1
Quiroga, M1
Willis, RN1
Mericle, RA1
Ulm, AJ1
Pierot, L1
Aggour, M1
Moret, J1
Jun, P1
Ko, NU1
English, JD1
Dowd, CF1
Halbach, VV1
Lawton, MT1
Sehy, JV1
Holloway, WE1
Lin, SP1
Cross, DT2
Stuart, RM1
Helbok, R1
Kurtz, P1
Schmidt, M1
Fernandez, L1
Lee, K1
Badjatia, N1
Mayer, SA1
Lavine, S1
Meyers, P1
Connolly, ES1
Claassen, J1
French, KF1
Hoesch, RE1
Allred, J1
Wilder, M1
Smith, AG1
Digre, KB1
La Barge, DV1
Ryerson, CJ1
Talke, PO1
Rahme, R1
Abruzzo, TA1
Zuccarello, M1
Ringer, A1
Feng, L1
Fitzsimmons, BF1
Young, WL1
Berman, MF1
Lin, E1
Aagaard, BD1
Duong, H1
Pile-Spellman, J1
Mazumdar, A1
Rivet, DJ1
Lavine, SD1
Wang, M1
Etu, JJ1
Meyers, PM1
Joshi, S1
Westhout, FD1
Nwagwu, CI1
Nishizawa, S1
Zhang, JH1
Keuskamp, J1
Murali, R1
Chao, KH1
Tanaka, Y1
Masuzawa, T1
Saito, M1
Yamada, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome[NCT02756416]10 participants (Anticipated)Interventional2016-07-31Not yet recruiting
The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study[NCT01996436]Phase 4330 participants (Anticipated)Interventional2016-08-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for verapamil and Angiospasm, Intracranial

ArticleYear
Verapamil in the treatment of reversible cerebral vasoconstriction syndrome: A systematic review.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2023, Volume: 113

    Topics: Cerebrovascular Disorders; Humans; Nimodipine; Vasoconstriction; Vasospasm, Intracranial; Verapamil

2023
Posttraumatic vasospasm detected by continuous brain tissue oxygen monitoring: treatment with intraarterial verapamil and balloon angioplasty.
    Neurocritical care, 2009, Volume: 10, Issue:1

    Topics: Adult; Angioplasty, Balloon; Brain Injuries; Female; Humans; Monitoring, Physiologic; Oxygen Consump

2009
Vasospasm after aneurysmal subarachnoid hemorrhage: recent advances in endovascular management.
    Current opinion in critical care, 2010, Volume: 16, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angioplasty, Balloon; Critical Care; Endovascular Pro

2010
[Basic research and treatment for cerebral vasospasm after subarachnoid hemorrhage: the present and future prospects].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Angioplasty, Balloon; Calcium Channel

2008

Trials

2 trials available for verapamil and Angiospasm, Intracranial

ArticleYear
[Intracisternal administration of verapamil for the prevention and treatment of vasospasm in patients after microsurgical treatment of cerebral aneurysms in the acute period of hemorrhage].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2019, Volume: 83, Issue:4

    Topics: Humans; Intracranial Aneurysm; Subarachnoid Hemorrhage; Treatment Outcome; Vasodilator Agents; Vasos

2019
Effect of intraarterial verapamil on the diameter of vasospastic intracranial arteries in patients with cerebral vasospasm.
    Neurosurgical focus, 2006, Sep-15, Volume: 21, Issue:3

    Topics: Cerebral Angiography; Cerebral Arteries; Dose-Response Relationship, Drug; Female; Humans; Infusions

2006

Other Studies

39 other studies available for verapamil and Angiospasm, Intracranial

ArticleYear
Intra-arterial Administration of Verapamil for the Prevention and Treatment of Cerebral Angiospasm.
    Acta neurochirurgica. Supplement, 2020, Volume: 127

    Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Child; Humans; Middle Aged; Subarachnoid Hemorrhage; Tr

2020
Intracranial Hemorrhage from Meningioma: 2 Novel Risk Factors.
    World neurosurgery, 2020, Volume: 135

    Topics: Basilar Artery; Cerebral Intraventricular Hemorrhage; Citalopram; Coma; Computed Tomography Angiogra

2020
Intra-Arterial Verapamil Treatment in Oral Therapy-Refractory Reversible Cerebral Vasoconstriction Syndrome.
    AJNR. American journal of neuroradiology, 2020, Volume: 41, Issue:2

    Topics: Adult; Aged; Cerebrovascular Disorders; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged

2020
Morphological changes of intracranial pressure quantifies vasodilatory effect of verapamil to treat cerebral vasospasm.
    Journal of neurointerventional surgery, 2020, Volume: 12, Issue:8

    Topics: Aged; Cerebrovascular Circulation; Female; Humans; Infusions, Intra-Arterial; Intracranial Pressure;

2020
Discrepancy in Neurologic Outcomes Following Aneurysmal Subarachnoid Hemorrhage as a Function of Socioeconomic Class.
    World neurosurgery, 2020, Volume: 138

    Topics: Female; Health Services Accessibility; Humans; Male; Microsurgery; Middle Aged; Retrospective Studie

2020
Use of single versus multiple vasodilator agents in the treatment of cerebral vasospasm: is more better than less?
    Acta neurochirurgica, 2021, Volume: 163, Issue:1

    Topics: Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nicardipine; Nitroglycerin; Retrospect

2021
Computational methods for visualizing and measuring verapamil efficacy for cerebral vasospasm.
    Scientific reports, 2020, 11-02, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Angiography, Digital Subtraction; Female; Humans; Male; Middle Aged; Perfusion Im

2020
The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
    Clinical neurology and neurosurgery, 2021, Volume: 202

    Topics: Aneurysm, Ruptured; Anticonvulsants; Brain Ischemia; Dose-Response Relationship, Drug; Female; Funct

2021
Chemical angioplasty for medically refractory reversible cerebral vasoconstriction syndrome
    British journal of neurosurgery, 2018, Volume: 32, Issue:4

    Topics: Angioplasty; Calcium Channel Blockers; Drug Resistance; Female; Humans; Infusions, Intra-Arterial; M

2018
Use of the PulseRider Device in the Treatment of Ruptured Intracranial Aneurysms: A Case Series.
    World neurosurgery, 2019, Volume: 127

    Topics: Abciximab; Adult; Aged; Aneurysm, Ruptured; Calcium Channel Blockers; Cerebral Angiography; Combined

2019
Effects of Intrathecal Verapamil on Cerebral Vasospasm in Experimental Rat Study.
    World neurosurgery, 2019, Volume: 127

    Topics: Animals; Calcium Channel Blockers; Injections, Spinal; Male; Oxidative Stress; Rats; Rats, Sprague-D

2019
[Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: case report].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2013, Volume: 77, Issue:4

    Topics: Acute Disease; Aged; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; Subarachnoid Hemorrh

2013
Verapamil-responsive coital cephalalgia as reversible cerebral vasoconstriction prodrome.
    Journal of neurology, 2014, Volume: 261, Issue:8

    Topics: Cerebral Angiography; Female; Headache; Humans; Imaging, Three-Dimensional; Middle Aged; Vasoconstri

2014
A case of reversible cerebral vasoconstriction syndrome presenting with recurrent neurological deficits: Evaluation using noninvasive arterial spin labeling MRI.
    Clinical neurology and neurosurgery, 2014, Volume: 126

    Topics: Calcium Channel Blockers; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Electro

2014
The detrimental clinical impact of severe angiographic vasospasm may be diminished by maximal medical therapy and intensive endovascular treatment.
    Journal of neurointerventional surgery, 2015, Volume: 7, Issue:12

    Topics: Adult; Endovascular Procedures; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Prospe

2015
Results of an International Survey on the Investigation and Endovascular Management of Cerebral Vasospasm and Delayed Cerebral Ischemia.
    World neurosurgery, 2015, Volume: 83, Issue:6

    Topics: Adult; Australasia; Brain Ischemia; Disease Management; Endovascular Procedures; Europe; Female; Hea

2015
Coil herniation following intra-arterial verapamil infusion for the treatment of cerebral vasospasm: Case report and literature review.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2015, Volume: 21, Issue:2

    Topics: Blood Vessel Prosthesis; Carotid Artery, Internal; Hemiplegia; Hernia; Humans; Infusions, Intra-Arte

2015
Posterior reversible encephalopathy syndrome with thalamic involvement during vasopressor treatment of vertebrobasilar vasospasm after subarachnoid hemorrhage.
    BMJ case reports, 2015, Dec-11, Volume: 2015

    Topics: Humans; Intracranial Aneurysm; Magnetic Resonance Imaging; Male; Middle Aged; Phenylephrine; Posteri

2015
Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016, Volume: 36, Issue:4

    Topics: Acute Disease; Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Calcium Channel Blockers; Cell

2016
Initial clinical experience with near-infrared spectroscopy in assessing cerebral tissue oxygen saturation in cerebral vasospasm before and after intra-arterial verapamil injection.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 26

    Topics: Adult; Aged; Brain; Cerebrovascular Circulation; Female; Humans; Injections, Intra-Arterial; Male; M

2016
Reversal of Visual Impairment Associated with Vasospasm After Resection of Sphenoclinoidocavernous Meningioma with Intra-Arterial Verapamil.
    World neurosurgery, 2016, Volume: 92

    Topics: Adrenal Cortex Hormones; Female; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging;

2016
Verapamil eluting stents as a possible treatment for vasospasm after subarachnoid hemorrhage.
    Journal of neurointerventional surgery, 2017, Volume: 9, Issue:9

    Topics: Coated Materials, Biocompatible; Drug-Eluting Stents; Humans; Microscopy, Electron, Scanning; Subara

2017
Reversible Cerebral Vasoconstriction Syndrome.
    The Journal of the Association of Physicians of India, 2016, Volume: 64, Issue:6

    Topics: Adult; Brain Infarction; Circle of Willis; Coronary Vasospasm; Female; Headache Disorders, Primary;

2016
Reversible cerebral vasoconstriction syndrome.
    Neuropsychological rehabilitation, 2018, Volume: 28, Issue:2

    Topics: Adult; Brain; Female; Headache Disorders, Primary; Humans; Neuropsychological Tests; Vasodilator Age

2018
Intra-arterial milrinone for reversible cerebral vasoconstriction syndrome.
    Headache, 2009, Volume: 49, Issue:1

    Topics: Anti-Inflammatory Agents; Brain; Calcium Channel Blockers; Cerebral Angiography; Female; Headache Di

2009
Intra-arterial calcium channel blocker infusion for treatment of severe vasospasm in traumatic brain injury: case report.
    Neurosurgery, 2008, Volume: 63, Issue:5

    Topics: Accidents, Traffic; Adult; Brain Injuries; Calcium Channel Blockers; Cerebral Angiography; Cerebral

2008
Near-complete resolution of angiographic cerebral vasospasm after extreme elevation of mean arterial pressure: case report.
    Surgical neurology, 2009, Volume: 72, Issue:4

    Topics: Calcium Channel Blockers; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Fema

2009
Ultrahigh-dose intraarterial infusion of verapamil through an indwelling microcatheter for medically refractory severe vasospasm: initial experience. Clinical article.
    Journal of neurosurgery, 2010, Volume: 113, Issue:4

    Topics: Adult; Aged; Calcium Channel Blockers; Catheterization; Catheters, Indwelling; Cerebral Angiography;

2010
Endovascular treatment of medically refractory cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
    AJNR. American journal of neuroradiology, 2010, Volume: 31, Issue:10

    Topics: Adult; Angioplasty; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Humans; Mal

2010
Improvement in angiographic cerebral vasospasm after intra-arterial verapamil administration.
    AJNR. American journal of neuroradiology, 2010, Volume: 31, Issue:10

    Topics: Adult; Calcium Channel Blockers; Cerebral Angiography; Female; Humans; Infusions, Intra-Arterial; Ma

2010
High-dose intra-arterial verapamil for the treatment of cerebral vasospasm after subarachnoid hemorrhage: prolonged effects on hemodynamic parameters and brain metabolism.
    Neurosurgery, 2011, Volume: 68, Issue:2

    Topics: Adult; Blood Pressure; Brain; Cerebrovascular Circulation; Female; Hemodynamics; Humans; Infusions,

2011
Repetitive use of intra-arterial verapamil in the treatment of reversible cerebral vasoconstriction syndrome.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:1

    Topics: Adult; Aged, 80 and over; Cerebral Arteries; Cerebrovascular Disorders; Female; Humans; Radiography;

2012
Hemodynamic stability after intraarterial injection of verapamil for cerebral vasospasm.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:6

    Topics: Adult; Anesthesia, General; Blood Pressure; British Columbia; Cerebral Arteries; Female; Heart Rate;

2012
Intra-arterial veramil-induced seizures: drug toxicity or rapid reperfusion?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2012, Volume: 39, Issue:4

    Topics: Accidents, Traffic; Adult; Anti-Arrhythmia Agents; Cerebral Angiography; Craniocerebral Trauma; Fema

2012
Intraarterially administered verapamil as adjunct therapy for cerebral vasospasm: safety and 2-year experience.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:8

    Topics: Calcium Channel Blockers; Cerebral Angiography; Female; Humans; Injections, Intra-Arterial; Male; Mi

2002
Augmentation of cerebral blood flow and reversal of endothelin-1-induced vasospasm: a comparison of intracarotid nicardipine and verapamil.
    Neurosurgery, 2007, Volume: 60, Issue:4

    Topics: Animals; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelin-1; Injections, In

2007
Intra-arterial verapamil-induced seizures: case report and review of the literature.
    Surgical neurology, 2007, Volume: 67, Issue:5

    Topics: Adult; Anticonvulsants; Aphasia, Broca; Carotid Artery, Internal; Female; Functional Laterality; Hum

2007
High-dose intraarterial verapamil in the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2008, Volume: 108, Issue:3

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Heart Rat

2008
Inhibitory effects of verapamil and nitroglycerin on contraction and cytosolic Ca2+ levels in cerebrovascular smooth muscle during chronic cerebral vasospasm.
    Neurologia medico-chirurgica, 2001, Volume: 41, Issue:5

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Cytosol; Disease Models, Anima

2001