Page last updated: 2024-10-24

verapamil and Angina at Rest

verapamil has been researched along with Angina at Rest in 28 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"We have studied the antiaggregatory effect of fenflumizole, a new non-steroidal antiinflammatory imidazole derivative, in ten patients with unstable angina pectoris."9.06The influence of fenflumizole on platelet aggregation in patients with unstable angina pectoris. ( Grande, P; Grauholt, AM; Wadt, J, 1987)
"Verapamil is well tolerated in patients with stable and unstable angina pectoris, as well as in patients with threatened infarction."8.80Verapamil in acute myocardial infarction. The rationales of the VAMI and DAVIT III trials. ( Jespersen, CM, 1999)
"Verapamil is well tolerated in patients with stable and unstable angina pectoris, as well as in patients with threatened infarction."8.80Verapamil in acute myocardial infarction. The rationales of the VAMI and DAVIT III trials. ( Jespersen, CM, 2000)
"Verapamil has been shown to be effective in reducing the frequency of episodes of ischemic pain in patients with unstable angina pectoris, and to be more effective than beta-adrenoceptor antagonists in such patients."7.67Verapamil in unstable angina pectoris: failure to demonstrate a relationship between efficacy and plasma levels. ( Elliott, SL; Horowitz, JD; Powell, AC, 1988)
"We have studied the antiaggregatory effect of fenflumizole, a new non-steroidal antiinflammatory imidazole derivative, in ten patients with unstable angina pectoris."5.06The influence of fenflumizole on platelet aggregation in patients with unstable angina pectoris. ( Grande, P; Grauholt, AM; Wadt, J, 1987)
"Verapamil is well tolerated in patients with stable and unstable angina pectoris, as well as in patients with threatened infarction."4.80Verapamil in acute myocardial infarction. The rationales of the VAMI and DAVIT III trials. ( Jespersen, CM, 1999)
"Verapamil is well tolerated in patients with stable and unstable angina pectoris, as well as in patients with threatened infarction."4.80Verapamil in acute myocardial infarction. The rationales of the VAMI and DAVIT III trials. ( Jespersen, CM, 2000)
" Although nifedipine is highly effective against vasospastic angina, its use in threatened myocardial infarction or severe unstable angina is not supported by recent studies, unless combined with a beta-blocker."4.77Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials. ( Opie, LH, 1988)
"Verapamil has been shown to be effective in reducing the frequency of episodes of ischemic pain in patients with unstable angina pectoris, and to be more effective than beta-adrenoceptor antagonists in such patients."3.67Verapamil in unstable angina pectoris: failure to demonstrate a relationship between efficacy and plasma levels. ( Elliott, SL; Horowitz, JD; Powell, AC, 1988)
"Patients with unstable angina pectoris have increased thrombocyte aggregation and disturbances in serum prostaglandin balance."2.67[Thrombocyte aggregation and serum thromboxane B2 in patients with unstable angina pectoris treated with diltiazem or verapamil]. ( Grande, P; Grauholt, AM; Holmvang, L; Lyck, F, 1992)
" The clinical syndrome was controlled by verapamil in 16 cases out of 20 (80% of cases) at the dosage of 360 mg/d in 14 patients and of 480 mg/d in two."2.67[Unstable angina and infarction without Q wave treated with verapamil: value of the early exercise test]. ( Ghadanfar, M; Guyon, P; Haiat, R; Halphen, C; Leroy, G; Richecoeur, J; Stoltz, JP, 1991)
"We report on a 46-year-old male with unstable angina pectoris due to a total proximal occlusion of the left circumflex artery."1.30[Anti-ischemic effect of verapamil within the scope of interventional recanalization]. ( Baumgart, D; Caspari, G; Eggebrecht, H; Erbel, R; Haude, M; Oldenburg, O; Schaar, J, 1999)
"They also have great potential for the treatment of hypertension, cerebrovascular disorders, and Raynaud's phenomenon."1.27Calcium channel blocking drugs. Part II: Clinical applications. ( Brill, DM; Fozzard, HA, 1985)
"Patients with unstable angina pectoris exhibited signs of platelet activation, i."1.27[Unstable stenocardia: indicators of platelet activity and the effect of verapamil]. ( Chikvashvili, DI; Gratsianskiĭ, NA; Masenko, VP, 1987)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199019 (67.86)18.7374
1990's8 (28.57)18.2507
2000's1 (3.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hugenholtz, PG2
Michels, R1
Serruys, PW1
Simoons, ML1
de Jong, JW1
Capucci, A3
Bracchetti, D2
Carini, G2
Di Ciò, G2
Maresta, A3
Magnani, B3
Singh, N1
Mironov, D1
Goodman, S1
Morgan, CD1
Langer, A1
Ergene, O1
Tastan, A1
Seyithanoglu, Y1
Nazli, C1
Kozan, O1
Ergene, U1
Keskin, V1
Hansen, JF1
Mellemgaard, K1
Jespersen, CM2
Oldenburg, O1
Baumgart, D1
Schaar, J1
Eggebrecht, H1
Caspari, G1
Haude, M1
Erbel, R1
Lyck, F1
Holmvang, L1
Grauholt, AM2
Grande, P2
Leroy, G1
Ghadanfar, M1
Guyon, P1
Richecoeur, J1
Halphen, C1
Stoltz, JP1
Haiat, R1
Yusuf, S1
Held, P1
Furberg, C1
Brill, DM1
Fozzard, HA1
Morrison, M1
Fairholm, S1
Freeman, MR1
Wadt, J1
Gratsianskiĭ, NA2
Chikvashvili, DI1
Masenko, VP1
Mauri, F1
Mafrici, A1
Biraghi, M1
Cerri, P1
De Biase, AM1
Opie, LH1
Sclarovsky, S1
Bassevich, R1
Klainman, E1
Rechavia, E1
Sagie, A1
Agmon, J1
Powell, AC1
Elliott, SL1
Horowitz, JD1
Pustovoĭt, GD1
Kukharchuk, VV1
Karpov, IuA3
Kutsenko, AI1
Noeva, EA2
Zaruba, AIu1
Ruda, MIa1
Marzocchi, A1
Galiè, N1
Marrozzini, C1
Winniford, MD1
Willerson, JT1
Hillis, LD1
Ceci, V1
Longo, A1
Di Mario, F1
Fiorella, AT1
Aiello, P1
Masini, V1

Reviews

4 reviews available for verapamil and Angina at Rest

ArticleYear
Verapamil in acute myocardial infarction. The rationales of the VAMI and DAVIT III trials.
    Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:4

    Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical Trials as Topic

1999
Verapamil in acute myocardial infarction. The rationales of the VAMI and DAVIT III trials.
    Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:1

    Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical Trials as Topic

2000
Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials.
    Cardiovascular drugs and therapy, 1988, Volume: 1, Issue:5

    Topics: Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Thera

1988
Calcium antagonists for acute ischemic heart disease.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Acute Disease; Angina Pectoris, Variant; Angina, Unstable; Calcium Channel Blockers; Coronary Diseas

1985

Trials

8 trials available for verapamil and Angina at Rest

ArticleYear
[Double-blind comparison of verapamil and propranolol in the therapy of unstable angina].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:5

    Topics: Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Female; Huma

1982
Treatment of silent ischemia in unstable angina: a randomized comparison of sustained-release verapamil versus metoprolol.
    Clinical cardiology, 1995, Volume: 18, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Angina, Unstable; Calcium Channel Blockers; Delayed-Action Prepar

1995
[Thrombocyte aggregation and serum thromboxane B2 in patients with unstable angina pectoris treated with diltiazem or verapamil].
    Ugeskrift for laeger, 1992, Oct-26, Volume: 154, Issue:44

    Topics: Angina, Unstable; Diltiazem; Drug Evaluation; Female; Humans; Male; Middle Aged; Pilot Projects; Pla

1992
[Unstable angina and infarction without Q wave treated with verapamil: value of the early exercise test].
    Annales de cardiologie et d'angeiologie, 1991, Volume: 40, Issue:6

    Topics: Adult; Aged; Angina, Unstable; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged

1991
Update of effects of calcium antagonists in myocardial infarction or angina in light of the second Danish Verapamil Infarction Trial (DAVIT-II) and other recent studies.
    The American journal of cardiology, 1991, Jun-01, Volume: 67, Issue:15

    Topics: Angina, Unstable; Calcium Channel Blockers; Denmark; Humans; Myocardial Infarction; Nicardipine; Nif

1991
The influence of fenflumizole on platelet aggregation in patients with unstable angina pectoris.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:5

    Topics: Adenosine Diphosphate; Adult; Aged; Angina Pectoris; Angina, Unstable; Anti-Inflammatory Agents; Ara

1987
Effectiveness of calcium antagonist drugs in patients with unstable angina and proven coronary artery disease.
    European heart journal, 1988, Volume: 9 Suppl N

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Calcium; Coronary Disease; Diltiazem; Electrocardiog

1988
Nifedipine compared with verapamil in unstable angina pectoris.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Drug Evaluation; Female; Follow-Up Studies; Humans;

1986

Other Studies

16 other studies available for verapamil and Angina at Rest

ArticleYear
Treatment of unstable angina with emphasis on calcium antagonists.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:11

    Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electroca

1984
Mechanism(s) of calcium antagonists and ischemia.
    Zeitschrift fur Kardiologie, 1984, Volume: 73 Suppl 2

    Topics: Adenosine Triphosphate; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Coronary Circul

1984
[Double-blind comparison between verapamil and propranolol in the therapy of unstable angina].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:5

    Topics: Aged; Angina Pectoris; Angina, Unstable; Double-Blind Method; Drug Evaluation; Female; Humans; Male;

1982
Catheter-induced vasospasm in the right external iliac and femoral arteries during a cardiac diagnostic procedure.
    International journal of cardiac imaging, 1999, Volume: 15, Issue:3

    Topics: Angina, Unstable; Arterial Occlusive Diseases; Catheterization, Peripheral; Chest Pain; Cineangiogra

1999
Angina pectoris, myocardial infarction and verapamil.
    Journal of the American College of Cardiology, 1999, Volume: 34, Issue:3

    Topics: Angina, Unstable; Calcium Channel Blockers; Heart Failure; Humans; Myocardial Infarction; Randomized

1999
[Anti-ischemic effect of verapamil within the scope of interventional recanalization].
    Herz, 1999, Volume: 24, Issue:7

    Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Blood Flow Velocity; Calcium Channel Blockers; Cor

1999
Calcium channel blocking drugs. Part II: Clinical applications.
    Comprehensive therapy, 1985, Volume: 11, Issue:10

    Topics: Angina Pectoris; Angina Pectoris, Variant; Angina, Unstable; Arrhythmias, Cardiac; Calcium Channel B

1985
New etiology for intestinal uptake of thallium-201.
    Clinical nuclear medicine, 1989, Volume: 14, Issue:10

    Topics: Angina, Unstable; Colon; Exercise Test; Female; Heart; Humans; Middle Aged; Radionuclide Imaging; Th

1989
[Unstable stenocardia: indicators of platelet activity and the effect of verapamil].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1987, Volume: 10, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; beta-Thromboglobulin; Blood Platelets; Humans; Male;

1987
Unstable angina with tachycardia: clinical and therapeutic implications.
    American heart journal, 1988, Volume: 116, Issue:5 Pt 1

    Topics: Aged; Amiodarone; Angina Pectoris; Angina, Unstable; Electrocardiography; Female; Heart Rate; Humans

1988
Verapamil in unstable angina pectoris: failure to demonstrate a relationship between efficacy and plasma levels.
    Therapeutic drug monitoring, 1988, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Female; Humans; Male; Middle Aged

1988
[Use of decimeter microwaves and drugs in patients with unstable stenocardia].
    Vrachebnoe delo, 1987, Issue:9

    Topics: Angina Pectoris; Angina, Unstable; Combined Modality Therapy; Delayed-Action Preparations; Drug Ther

1987
[Clinical effectiveness of plasmapheresis in patients with unstable stenocardia refractory to drug therapy].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1987, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Angina Pectoris; Angina, Unstable; Humans; Middle Aged; Nitrates; Plasmaphe

1987
[Unstable stenocardia: hemodynamic effect of the intravenous administration of verapamil].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:5

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Blood Pressure; Cardiac Output; Cardiac Volume; Hear

1986
[Use of verapamil for treating patients with unstable stenocardia].
    Kardiologiia, 1985, Volume: 25, Issue:5

    Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Angina, Unstable; Delayed-Action Preparations; D

1985
[Comparison between atenolol and verapamil in the treatment of unstable angina].
    Recenti progressi in medicina, 1985, Volume: 76, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Arrhythmias, Cardiac; Atenolol; Drug Evaluation; Hum

1985