Page last updated: 2024-10-24

verapamil and Anasarca

verapamil has been researched along with Anasarca in 22 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"We studied the effect of verapamil on intestinal ischemia and reperfusion (I/R) injury."7.70Beneficial effects of verapamil on intestinal ischemia and reperfusion injury: pretreatment versus postischemic treatment. ( Fujii, Y; Kataoka, M; Kato, T; Kimura, M; Kuwabara, Y; Narita, K; Okahira, T; Sato, A, 1998)
"The authors examined the efficacy and safety of the combination of verapamil and nifedipine in the control of hypertension."7.69Verapamil and nifedipine in combination for the treatment of hypertension. ( Bottini, PB; Carr, AA; Kaesemeyer, WH; Prisant, LM, 1994)
" The effects of the calcium channel blockers, verapamil and nifedipine on myocardial ischaemia and oedema evoked by endothelin-1 (ET-1) or IRL 1620, an ETB receptor-selective agonist were studied in anaesthetized and conscious rats."7.69Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat. ( Filep, JG; Földes-Filep, E; Fournier, A; Skrobik, Y, 1996)
"When verapamil was combined with diclofenac, in vitro, the inhibitory effect on PMA or OPZ-induced CL response was synergistic."5.28Verapamil enhances the inhibitory effect of diclofenac on the chemiluminescence of human polymorphonuclear leukocytes and carrageenan-induced rat's paw oedema. ( al-Tuwaijri, AS; Mustafa, AA, 1992)
"002; multivariate analysis of variance), with 7 significant univariate treatment effects, all favoring COER-verapamil, being noted-pedal edema, polyuria, rapid heart beat or palpitations, hives, muscle cramps, abdominal cramps, and headaches."5.09Physical Symptoms Distress Index: a sensitive tool to evaluate the impact of pharmacological agents on quality of life. ( Anderson, RB; Hollenberg, NK; Williams, GH, 1999)
" In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis."3.80Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014)
"We studied the effect of verapamil on intestinal ischemia and reperfusion (I/R) injury."3.70Beneficial effects of verapamil on intestinal ischemia and reperfusion injury: pretreatment versus postischemic treatment. ( Fujii, Y; Kataoka, M; Kato, T; Kimura, M; Kuwabara, Y; Narita, K; Okahira, T; Sato, A, 1998)
"The authors examined the efficacy and safety of the combination of verapamil and nifedipine in the control of hypertension."3.69Verapamil and nifedipine in combination for the treatment of hypertension. ( Bottini, PB; Carr, AA; Kaesemeyer, WH; Prisant, LM, 1994)
" The effects of the calcium channel blockers, verapamil and nifedipine on myocardial ischaemia and oedema evoked by endothelin-1 (ET-1) or IRL 1620, an ETB receptor-selective agonist were studied in anaesthetized and conscious rats."3.69Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat. ( Filep, JG; Földes-Filep, E; Fournier, A; Skrobik, Y, 1996)
" The 5-HT2 receptor-antagonistic properties of AHR-16303B were demonstrated by inhibition of (a) [3H]ketanserin binding to rat cerebral cortical membranes (IC50 = 165 nM); (b) 5-hydroxytryptamine (5-HT)-induced foot edema in rats (minimum effective dose, (MED) = 0."3.68AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels. ( Appell, KC; Barrett, RJ; Kilpatrick, BF; Nolan, JC; Proakis, AG; Walsh, DA, 1991)
"Carrageenin oedema is enhanced by the simultaneous injection in the rat paw of platelet activating factor (PAF)."1.29Platelet activating factor potentiates rat paw oedema induced by different phlogogen agents. ( Autore, G; Capasso, F; Di Carlo, G; Di Urno, MV; Izzo, AA; Mascolo, N, 1994)
"When verapamil was combined with diclofenac, in vitro, the inhibitory effect on PMA or OPZ-induced CL response was synergistic."1.28Verapamil enhances the inhibitory effect of diclofenac on the chemiluminescence of human polymorphonuclear leukocytes and carrageenan-induced rat's paw oedema. ( al-Tuwaijri, AS; Mustafa, AA, 1992)
"A case of severe nonimmune hydrops fetalis caused by supraventricular tachycardia is presented."1.27Insufficient transplacental digoxin transfer in severe hydrops fetalis. ( Granat, M; Younis, JS, 1987)
"If oedema is associated with fetal cardiac arrhythmic conditions it can in certain cases be treated and cured in utero."1.27[Prenatal echographic diagnosis of fetoplacental anasarca]. ( de Grandi, P; Nguyen The, H; Stadlin, M, 1985)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19908 (36.36)18.7374
1990's10 (45.45)18.2507
2000's1 (4.55)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khan, H2
Saeed, M2
Mehmood, MH2
Rehman, NU2
Muhammad, N2
Haq, IU2
Ashraf, N1
El-Tahir, KE1
Gilani, AH2
Abbas, M1
Zhu, JJ1
Xu, YQ1
He, JH1
Yu, HP1
Huang, CJ1
Gao, JM1
Dong, QX1
Xuan, YX1
Li, CQ1
Tobin, J1
Flitman, S1
Goldenberg, MM1
Meurer, RD1
Sobotka, MA1
Exalto, N1
Dijkhuizen, GH1
van der Vorm, DH1
Izzo, AA1
Mascolo, N1
Di Urno, MV1
Autore, G1
Di Carlo, G1
Capasso, F1
Nagahisa, A1
Asai, R1
Kanai, Y1
Murase, A1
Tsuchiya-Nakagaki, M1
Nakagaki, T1
Shieh, TC1
Taniguchi, K1
Kaesemeyer, WH1
Carr, AA1
Bottini, PB1
Prisant, LM1
Battalora, MS1
Johnston, DA1
DiGiovanni, J1
Filep, JG1
Skrobik, Y1
Fournier, A1
Földes-Filep, E1
Taherzadeh, M1
Warren, JB1
Kimura, M1
Kataoka, M1
Kuwabara, Y1
Sato, A1
Kato, T1
Narita, K1
Okahira, T1
Fujii, Y1
Anderson, RB1
Hollenberg, NK1
Williams, GH1
al-Tuwaijri, AS1
Mustafa, AA1
Barrett, RJ1
Appell, KC1
Kilpatrick, BF1
Proakis, AG1
Nolan, JC1
Walsh, DA1
Srivastava, VK1
Saxena, KK1
Gupta, B1
Maxwell, DJ1
Crawford, DC1
Curry, PV1
Tynan, MJ1
Allan, LD1
Younis, JS1
Granat, M1
Castro, R1
Perera, C1
Doménech, E1
Méndez, A1
Ormazábal, C1
Nguyen The, H1
Stadlin, M1
de Grandi, P1
Kaltenbach, M1
Hopf, R1

Trials

1 trial available for verapamil and Anasarca

ArticleYear
Physical Symptoms Distress Index: a sensitive tool to evaluate the impact of pharmacological agents on quality of life.
    Archives of internal medicine, 1999, Apr-12, Volume: 159, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Constipation; Dou

1999

Other Studies

21 other studies available for verapamil and Anasarca

ArticleYear
Studies on tracheorelaxant and anti-inflammatory activities of rhizomes of Polygonatum verticillatum.
    BMC complementary and alternative medicine, 2013, Jul-29, Volume: 13

    Topics: Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Carbachol; Carrageenan; Edema; Female;

2013
Bronchodilator activity of aerial parts of Polygonatum verticillatum augmented by anti-inflammatory activity: attenuation of Ca²⁺ channels and lipoxygenase.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Carra

2013
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease

2014
Cluster-like headaches associated with internal carotid artery dissection responsive to verapamil.
    Headache, 2008, Volume: 48, Issue:3

    Topics: Anticoagulants; Blepharoptosis; Carotid Artery, Internal, Dissection; Cluster Headache; Diagnosis, D

2008
A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat.
    Prostaglandins, 1984, Volume: 28, Issue:2

    Topics: Animals; Carrageenan; Dexamethasone; Dose-Response Relationship, Drug; Edema; Hindlimb; Indomethacin

1984
[Fetal hydrops as a result of supraventricular tachycardia].
    Nederlands tijdschrift voor geneeskunde, 1983, Sep-10, Volume: 127, Issue:37

    Topics: Adult; Cesarean Section; Digoxin; Edema; Female; Fetal Diseases; Humans; Infant, Newborn; Male; Preg

1983
Platelet activating factor potentiates rat paw oedema induced by different phlogogen agents.
    Agents and actions, 1994, Volume: 41, Issue:3-4

    Topics: Animals; Bradykinin; Carrageenan; Cellulose; Dextrans; Dinoprostone; Diterpenes; Drug Synergism; Ede

1994
Non-specific activity of (+/-)CP-96,345 in models of pain and inflammation.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Hyp

1993
Verapamil and nifedipine in combination for the treatment of hypertension.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Drug Therapy, Combination; Edema; Female

1994
The effects of calcium antagonists on anthrone skin tumor promotion and promoter-related effects in SENCAR mice.
    Cancer letters, 1995, Nov-27, Volume: 98, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Calcium; Calcium Channel Blockers; Carcinoge

1995
Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: Albumins; Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Edema

1996
Comparison of diltiazem and verapamil on rat microvascular permeability.
    Microvascular research, 1997, Volume: 54, Issue:3

    Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Diltiazem; Edema; Evans Blue; Injections,

1997
Beneficial effects of verapamil on intestinal ischemia and reperfusion injury: pretreatment versus postischemic treatment.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1998, Volume: 30, Issue:3

    Topics: Animals; Edema; Intestinal Diseases; Intestines; Ischemia; Magnetic Resonance Spectroscopy; Male; Ra

1998
Verapamil enhances the inhibitory effect of diclofenac on the chemiluminescence of human polymorphonuclear leukocytes and carrageenan-induced rat's paw oedema.
    International journal of immunopharmacology, 1992, Volume: 14, Issue:1

    Topics: Animals; Cell Survival; Diclofenac; Drug Synergism; Edema; Luminescent Measurements; Male; Neutrophi

1992
AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:1

    Topics: Animals; Atrial Function; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Calci

1991
Calcium channel blockers in acute inflammation.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:1

    Topics: Animals; Carrageenan; Edema; Female; Foot; Histamine; Hyaluronoglucosaminidase; Inflammation; Male;

1988
Obstetric importance, diagnosis, and management of fetal tachycardias.
    BMJ (Clinical research ed.), 1988, Jul-09, Volume: 297, Issue:6641

    Topics: Delivery, Obstetric; Digoxin; Drug Therapy, Combination; Edema; Female; Fetal Diseases; Heart Failur

1988
Insufficient transplacental digoxin transfer in severe hydrops fetalis.
    American journal of obstetrics and gynecology, 1987, Volume: 157, Issue:5

    Topics: Adult; Digoxin; Edema; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Pregnancy; Propranol

1987
[Hydrops fetalis caused by supraventricular tachycardia: effects of the administration of verapamil].
    Anales espanoles de pediatria, 1986, Volume: 25, Issue:6

    Topics: Edema; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy; Tachycardia, Supra

1986
[Prenatal echographic diagnosis of fetoplacental anasarca].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1985, Volume: 14, Issue:8

    Topics: Adult; Digoxin; Edema; Female; Fetal Diseases; Humans; Pregnancy; Tachycardia; Ultrasonography; Vera

1985
Treatment of hypertrophic cardiomyopathy: relation to pathological mechanisms.
    Journal of molecular and cellular cardiology, 1985, Volume: 17 Suppl 2

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiac Catheterization; Cardio

1985