verapamil has been researched along with Allodynia in 4 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Spinal pretreatment with cyclooxygenase (10 and 30 microg (S)-(+)-ibuprofen; and 3 and 30 microg ketorolac) and nitric oxide synthase (33 and 100 microg N(G) Nitro-L-arginine methyl ester hydrochloride (L-NAME) and 10 microg thiocitrulline) inhibitors resulted in no specific anti-allodynia." | 3.74 | Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase. ( Doom, CM; Maruyama, KP; Nanigian, DB; Sorkin, LS, 2008) |
| "Peripheral nerve demyelination was produced in adult rats by placing loosely-constrictive ligatures around the common sciatic nerve." | 1.28 | [Ca2+ channels and the abnormal electrical activity of demyelinated nerve]. ( Xiao, W; Xie, Y, 1992) |
| "Norepinephrine does not produce hyperalgesia in untreated skin, but in chloroform pretreated skin or in the presence of the calcium ionophore A23187, norepinephrine produces a potent dose-dependent hyperalgesia." | 1.28 | Characterization of distinct phospholipases mediating bradykinin and noradrenaline hyperalgesia. ( Heller, PH; Levine, JD; Taiwo, YO, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sorkin, LS | 1 |
| Doom, CM | 1 |
| Maruyama, KP | 1 |
| Nanigian, DB | 1 |
| Nagahisa, A | 1 |
| Asai, R | 1 |
| Kanai, Y | 1 |
| Murase, A | 1 |
| Tsuchiya-Nakagaki, M | 1 |
| Nakagaki, T | 1 |
| Shieh, TC | 1 |
| Taniguchi, K | 1 |
| Xiao, W | 1 |
| Xie, Y | 1 |
| Taiwo, YO | 1 |
| Heller, PH | 1 |
| Levine, JD | 1 |
4 other studies available for verapamil and Allodynia
| Article | Year |
|---|---|
Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase.
Topics: Animals; Behavior, Animal; Burns; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Diltiazem; En | 2008 |
Non-specific activity of (+/-)CP-96,345 in models of pain and inflammation.
Topics: Animals; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Hyp | 1993 |
[Ca2+ channels and the abnormal electrical activity of demyelinated nerve].
Topics: Animals; Calcium; Calcium Channels; Demyelinating Diseases; Electrophysiology; Hyperalgesia; Lanthan | 1992 |
Characterization of distinct phospholipases mediating bradykinin and noradrenaline hyperalgesia.
Topics: Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Fluorescent D | 1990 |