verapamil has been researched along with Adjuvant Arthritis in 6 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated (i) the effectiveness of glucosamine (GlcN) in treating adjuvant arthritis (AA) and its cardiac abnormalities (down regulation of cardiac calcium channel and beta-adrenergic proteins) (ii) the effect of AA on pharmacokinetics of GlcN and the cardiac ryanodine-2 target protein." | 7.78 | Glucosamine and adjuvant arthritis: a pharmacokinetic and pharmacodynamic study. ( Gilzad-Kohan, MH; Jamali, F, 2012) |
| " On day 6, rats were administered with single s." | 5.35 | The effect of infliximab on hepatic cytochrome P450 and pharmacokinetics of verapamil in rats with pre-adjuvant arthritis: a drug-disease and drug-drug interaction. ( Jamali, F; Ling, S, 2009) |
| "The objective of this study was to evaluate the suitability of the early phase of adjuvant arthritis (pre-AA) as a model of inflammation for pharmacokinetic studies." | 5.33 | Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies. ( Jamali, F; Ling, S, 2005) |
| "We investigated (i) the effectiveness of glucosamine (GlcN) in treating adjuvant arthritis (AA) and its cardiac abnormalities (down regulation of cardiac calcium channel and beta-adrenergic proteins) (ii) the effect of AA on pharmacokinetics of GlcN and the cardiac ryanodine-2 target protein." | 3.78 | Glucosamine and adjuvant arthritis: a pharmacokinetic and pharmacodynamic study. ( Gilzad-Kohan, MH; Jamali, F, 2012) |
| "Treatment of verapamil attenuated inflammation as well as joint destruction in arthritis models." | 1.43 | Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice. ( Li, W; Li, Z; Liu, Y; Meng, Q; Pan, J; Wang, W; Wang, X; Yan, P; Zhai, Y; Zhang, H; Zhang, P; Zhang, Z; Zhao, Y, 2016) |
| " On day 6, rats were administered with single s." | 1.35 | The effect of infliximab on hepatic cytochrome P450 and pharmacokinetics of verapamil in rats with pre-adjuvant arthritis: a drug-disease and drug-drug interaction. ( Jamali, F; Ling, S, 2009) |
| "The objective of this study was to evaluate the suitability of the early phase of adjuvant arthritis (pre-AA) as a model of inflammation for pharmacokinetic studies." | 1.33 | Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies. ( Jamali, F; Ling, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Li, Z | 1 |
| Meng, Q | 1 |
| Zhang, P | 1 |
| Yan, P | 1 |
| Zhang, Z | 1 |
| Zhang, H | 1 |
| Pan, J | 1 |
| Zhai, Y | 1 |
| Liu, Y | 1 |
| Wang, X | 1 |
| Li, W | 1 |
| Zhao, Y | 1 |
| Duan, C | 1 |
| Guo, JM | 1 |
| Dai, Y | 1 |
| Xia, YF | 1 |
| Ling, S | 2 |
| Jamali, F | 3 |
| Gilzad-Kohan, MH | 1 |
| Fontaine, J | 1 |
| Herchuelz, A | 1 |
| Famaey, JP | 1 |
6 other studies available for verapamil and Adjuvant Arthritis
| Article | Year |
|---|---|
Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice.
Topics: Animals; Arthritis, Experimental; Calcium Channel Blockers; Collagen; Inflammation; Inflammation Med | 2016 |
The absorption enhancement of norisoboldine in the duodenum of adjuvant-induced arthritis rats involves the impairment of P-glycoprotein.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; ATP Binding Cassette Transpor | 2017 |
The effect of infliximab on hepatic cytochrome P450 and pharmacokinetics of verapamil in rats with pre-adjuvant arthritis: a drug-disease and drug-drug interaction.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arthritis, Experimental; C-Reactive Prote | 2009 |
Glucosamine and adjuvant arthritis: a pharmacokinetic and pharmacodynamic study.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Arthritis, Experimental; Calcium Channel | 2012 |
Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Blood Proteins; Cytochrome P-450 Enzyme Syst | 2005 |
A pharmacological analysis of the responses of isolated aorta from rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Calcium; In Vitro Techniques; Male; Muscle Contraction; | 1984 |