verapamil has been researched along with Acute Brain Injuries in 12 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with verapamil (1." | 1.33 | Verapamil prevents, in a dose-dependent way, the loss of ChAT-immunoreactive neurons in the cerebral cortex following lesions of the rat nucleus basalis magnocellularis. ( Caballero-Bleda, M; Popović, M; Popović, N; Puelles, L; van Groen, T; Witter, MP, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, YY | 1 |
| Gao, YX | 1 |
| Gao, W | 1 |
| Xu, Y | 1 |
| Xu, YZ | 1 |
| Wang, YJ | 1 |
| Chang, S | 1 |
| Yu, LG | 1 |
| Zhang, LY | 1 |
| Liao, H | 1 |
| Yang, LF | 1 |
| Pang, T | 1 |
| Qiu, WW | 1 |
| Hwang, JJ | 1 |
| Sherwin, RS | 1 |
| Shahlaie, K | 1 |
| Boggan, JE | 1 |
| Latchaw, RE | 1 |
| Ji, C | 1 |
| Muizelaar, JP | 1 |
| Lee, DJ | 1 |
| Moftakhar, P | 1 |
| Glenn, TC | 1 |
| Vespa, PM | 1 |
| Martin, NA | 1 |
| Maeda, T | 1 |
| Lee, SM | 1 |
| Hovda, DA | 1 |
| Popović, M | 1 |
| Caballero-Bleda, M | 1 |
| Popović, N | 1 |
| Puelles, L | 1 |
| van Groen, T | 1 |
| Witter, MP | 1 |
| Okiyama, K | 2 |
| Rosenkrantz, TS | 1 |
| Smith, DH | 2 |
| Gennarelli, TA | 1 |
| McIntosh, TK | 2 |
| Matyja, E | 1 |
| Kida, E | 1 |
| Ciani, E | 1 |
| Baldinotti, I | 1 |
| Contestabile, A | 1 |
| Thomas, MJ | 1 |
| Damron, DS | 1 |
| Dorman, RV | 1 |
| Koenig, H | 1 |
| Goldstone, AD | 1 |
| Lu, CY | 1 |
1 review available for verapamil and Acute Brain Injuries
| Article | Year |
|---|---|
Posttraumatic vasospasm detected by continuous brain tissue oxygen monitoring: treatment with intraarterial verapamil and balloon angioplasty.
Topics: Adult; Angioplasty, Balloon; Brain Injuries; Female; Humans; Monitoring, Physiologic; Oxygen Consump | 2009 |
11 other studies available for verapamil and Acute Brain Injuries
| Article | Year |
|---|---|
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury.
Topics: Animals; Brain Injuries; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Drug Design; G | 2015 |
Verapamil is a potential therapy for hypoglycaemic brain injury.
Topics: Brain; Brain Injuries; Cognitive Dysfunction; Humans; Hypoglycemia; Hypoglycemic Agents; Verapamil | 2018 |
Intra-arterial calcium channel blocker infusion for treatment of severe vasospasm in traumatic brain injury: case report.
Topics: Accidents, Traffic; Adult; Brain Injuries; Calcium Channel Blockers; Cerebral Angiography; Cerebral | 2008 |
Restoration of cerebral vasoreactivity by an L-type calcium channel blocker following fluid percussion brain injury.
Topics: Animals; Antipyrine; Blood Pressure; Brain Injuries; Calcium; Calcium Channel Blockers; Calcium Chan | 2005 |
Verapamil prevents, in a dose-dependent way, the loss of ChAT-immunoreactive neurons in the cerebral cortex following lesions of the rat nucleus basalis magnocellularis.
Topics: Analysis of Variance; Animals; Basal Nucleus of Meynert; Brain Injuries; Calcium Channel Blockers; C | 2006 |
(S)-emopamil attenuates acute reduction in regional cerebral blood flow following experimental brain injury.
Topics: Animals; Brain Injuries; Brain Stem; Calcium Channel Blockers; Cerebellum; Cerebrovascular Circulati | 1994 |
Verapamil reduces quinolinic acid-induced neuronal damage in rat hippocampus in vitro.
Topics: Animals; Brain Injuries; Dendritic Cells; Hippocampus; In Vitro Techniques; Microscopy, Electron; Ne | 1993 |
Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury.
Topics: Animals; Basal Nucleus of Meynert; Brain; Brain Injuries; Calcium Channel Blockers; Choline O-Acetyl | 2001 |
Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury.
Topics: Animals; Blood Pressure; Brain Edema; Brain Injuries; Calcium Channel Blockers; Male; Memory; Psycho | 1992 |
Calcium-dependent phospholipid catabolism and arachidonic acid mobilization in cerebral minces.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Brain Injuries; Calcium; Egtazic Acid; Kinetics | 1990 |
Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin.
Topics: Animals; Aspirin; Blood-Brain Barrier; Brain; Brain Injuries; Cold Temperature; Cycloheximide; Dacti | 1989 |