verapamil has been researched along with Achalasia in 6 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Verapamil hydrochloride is an organic calcium antagonist that is known to decrease the contraction of smooth muscle." | 5.27 | The effect of verapamil on the lower esophageal sphincter pressure in normal subjects and in achalasia. ( Becker, BS; Burakoff, R, 1983) |
| "Verapamil and diltiazem have been shown in animals (opossum, baboon) to produce decreased contractions in esophageal smooth muscle, resulting in a decreased amplitude of peristalsis and decreased lower esophageal sphincter pressures." | 3.75 | Calcium-channel blocking agents for gastrointestinal disorders. ( Castell, DO, 1985) |
| "Verapamil hydrochloride is an organic calcium antagonist that is known to decrease the contraction of smooth muscle." | 1.27 | The effect of verapamil on the lower esophageal sphincter pressure in normal subjects and in achalasia. ( Becker, BS; Burakoff, R, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Traube, M | 1 |
| McCallum, RW | 1 |
| Becker, BS | 1 |
| Burakoff, R | 2 |
| Triadafilopoulos, G | 1 |
| Aaronson, M | 1 |
| Sackel, S | 1 |
| Palombo, C | 1 |
| Mian, M | 1 |
| Bertelli, A | 1 |
| Castell, DO | 1 |
| Schroeder, JS | 1 |
4 reviews available for verapamil and Achalasia
| Article | Year |
|---|---|
Calcium-channel blockers and the gastrointestinal tract. American College of Gastroenterology's Committee on FDA related matters.
Topics: Animals; Calcium Channel Blockers; Digestive System; Diltiazem; Esophageal Achalasia; Esophageal Dis | 1984 |
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach | 1989 |
Calcium-channel blocking agents for gastrointestinal disorders.
Topics: Animals; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Esophageal Achalasia; Esopha | 1985 |
Combination therapy with isosorbide dinitrate: current status and the future.
Topics: Angina Pectoris; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Esophageal Achalasia; Exe | 1985 |
2 trials available for verapamil and Achalasia
| Article | Year |
|---|---|
Medical treatment of esophageal achalasia. Double-blind crossover study with oral nifedipine, verapamil, and placebo.
Topics: Administration, Oral; Double-Blind Method; Esophageal Achalasia; Esophagogastric Junction; Esophagus | 1991 |
Calcium-channel blocking agents for gastrointestinal disorders.
Topics: Animals; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Esophageal Achalasia; Esopha | 1985 |
1 other study available for verapamil and Achalasia
| Article | Year |
|---|---|
The effect of verapamil on the lower esophageal sphincter pressure in normal subjects and in achalasia.
Topics: Adult; Blood Pressure; Esophageal Achalasia; Esophagogastric Junction; Female; Humans; Male; Manomet | 1983 |