Page last updated: 2024-10-24

verapamil and Achalasia

verapamil has been researched along with Achalasia in 6 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"Verapamil hydrochloride is an organic calcium antagonist that is known to decrease the contraction of smooth muscle."5.27The effect of verapamil on the lower esophageal sphincter pressure in normal subjects and in achalasia. ( Becker, BS; Burakoff, R, 1983)
"Verapamil and diltiazem have been shown in animals (opossum, baboon) to produce decreased contractions in esophageal smooth muscle, resulting in a decreased amplitude of peristalsis and decreased lower esophageal sphincter pressures."3.75Calcium-channel blocking agents for gastrointestinal disorders. ( Castell, DO, 1985)
"Verapamil hydrochloride is an organic calcium antagonist that is known to decrease the contraction of smooth muscle."1.27The effect of verapamil on the lower esophageal sphincter pressure in normal subjects and in achalasia. ( Becker, BS; Burakoff, R, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Traube, M1
McCallum, RW1
Becker, BS1
Burakoff, R2
Triadafilopoulos, G1
Aaronson, M1
Sackel, S1
Palombo, C1
Mian, M1
Bertelli, A1
Castell, DO1
Schroeder, JS1

Reviews

4 reviews available for verapamil and Achalasia

ArticleYear
Calcium-channel blockers and the gastrointestinal tract. American College of Gastroenterology's Committee on FDA related matters.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:11

    Topics: Animals; Calcium Channel Blockers; Digestive System; Diltiazem; Esophageal Achalasia; Esophageal Dis

1984
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
    La Clinica terapeutica, 1989, Feb-15, Volume: 128, Issue:3

    Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach

1989
Calcium-channel blocking agents for gastrointestinal disorders.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Esophageal Achalasia; Esopha

1985
Combination therapy with isosorbide dinitrate: current status and the future.
    American heart journal, 1985, Volume: 110, Issue:1 Pt 2

    Topics: Angina Pectoris; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Esophageal Achalasia; Exe

1985

Trials

2 trials available for verapamil and Achalasia

ArticleYear
Medical treatment of esophageal achalasia. Double-blind crossover study with oral nifedipine, verapamil, and placebo.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:3

    Topics: Administration, Oral; Double-Blind Method; Esophageal Achalasia; Esophagogastric Junction; Esophagus

1991
Calcium-channel blocking agents for gastrointestinal disorders.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Esophageal Achalasia; Esopha

1985

Other Studies

1 other study available for verapamil and Achalasia

ArticleYear
The effect of verapamil on the lower esophageal sphincter pressure in normal subjects and in achalasia.
    The American journal of gastroenterology, 1983, Volume: 78, Issue:12

    Topics: Adult; Blood Pressure; Esophageal Achalasia; Esophagogastric Junction; Female; Humans; Male; Manomet

1983