Page last updated: 2024-10-24

verapamil and Absence Seizure

verapamil has been researched along with Absence Seizure in 41 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"High-dose IA verapamil treatment is well-tolerated in the high-risk aneurysmal subarachnoid hemorrhage population that experience severe, symptomatic CVS with good functional outcomes at follow-up."8.02The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Esplin, N; Gigliotti, MJ; Mao, G; Sexton, K, 2021)
"The present study was focused to characterize the effects of intrahippocampal application of R-verapamil, a P-glycoprotein blocker, and High Frequency Electrical Stimulation (HFS) at 130 Hz, on seizure susceptibility and extracellular concentrations of glutamate and γ-aminobutyric acid (GABA) in hippocampus of kindled rats with drug-resistant seizures."7.77Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. ( Luna-Munguia, H; Orozco-Suarez, S; Rocha, L, 2011)
" Intra-arterial verapamil was started; during this treatment, the patient developed right-sided focal motor seizures."7.74Intra-arterial verapamil-induced seizures: case report and review of the literature. ( Nwagwu, CI; Westhout, FD, 2007)
"Oxcarbazepine is indicated for the treatment of partial or generalised tonic-clonic seizures."5.24Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects. ( Alexandre Junior, V; Antunes, NJ; Coelho, EB; Della Pasqua, O; Lanchote, VL; Takayanagui, OM; Tozatto, E; van Dijkman, SC; van Hasselt, JGC; Wichert-Ana, L, 2017)
"1 mg/kg of verapamil, administered immediately before anesthesia, significantly reduces the increase in peak heart rate and mean arterial blood pressure after electroconvulsive therapy."5.10Intravenous verapamil blunts hyperdynamic responses during electroconvulsive therapy without altering seizure activity. ( Imanaga, K; Inoue, T; Ogawa, R; Ogura, A; Shiga, T; Wajima, Z; Yoshikawa, T, 2002)
"High-dose IA verapamil treatment is well-tolerated in the high-risk aneurysmal subarachnoid hemorrhage population that experience severe, symptomatic CVS with good functional outcomes at follow-up."4.02The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Esplin, N; Gigliotti, MJ; Mao, G; Sexton, K, 2021)
" Thirty mice that developed seizures were randomly divided into three groups and administered PHT as well as the following treatments: saline (negative control); verapamil (20 mg/kg, positive control); and G."3.81Reversal of P-glycoprotein overexpression by Ginkgo biloba extract in the brains of pentylenetetrazole-kindled and phenytoin-treated mice. ( Chen, SL; Fan, Q; Ma, H; Zhang, C, 2015)
"The present study was focused to characterize the effects of intrahippocampal application of R-verapamil, a P-glycoprotein blocker, and High Frequency Electrical Stimulation (HFS) at 130 Hz, on seizure susceptibility and extracellular concentrations of glutamate and γ-aminobutyric acid (GABA) in hippocampus of kindled rats with drug-resistant seizures."3.77Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. ( Luna-Munguia, H; Orozco-Suarez, S; Rocha, L, 2011)
" Intra-arterial verapamil was started; during this treatment, the patient developed right-sided focal motor seizures."3.74Intra-arterial verapamil-induced seizures: case report and review of the literature. ( Nwagwu, CI; Westhout, FD, 2007)
") potentiated the anticonvulsant properties of phenytoin, phenobarbital and valproate against audiogenic seizures in DBA/2 mice."3.68Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice. ( De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR, 1992)
"The presenting symptoms, course, and treatment of 10 patients with severe theophylline toxicity (heart rate above 120, multifocal atrial tachycardia or premature ventricular contractions, hypotension, seizures) are described."3.67Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion. ( Greenberg, A; Kroboth, PD; Piraino, BH; Weiss, J, 1984)
"Nimodipine, a calcium channel blocker with high affinity for central dihydropyridine Ca2+ channels, produced a dose-dependent suppression of electrically induced seizures in the rabbit."3.67Inhibition of electrically induced seizures by a dihydropyridine calcium channel blocker. ( Anderson, RE; Meyer, FB; Sharbrough, FW; Sundt, TM; Tally, PW; Yaksh, TL, 1986)
" In the present investigations the action of the calcium antagonist verapamil on generalized tonic-clonic seizures was studied."3.67Suppression of recurrent generalized tonic-clonic seizure discharges by intraventricular perfusion of a calcium antagonist. ( Speckmann, EJ; Walden, J, 1988)
"Three calcium channel blockers were studied for efficacy in preventing seizures and death from cocaine intoxication."3.67Potentiation of cocaine toxicity with calcium channel blockers. ( Albertson, TE; Derlet, RW, 1989)
"Nimodipine, a dihydropyridine that interacts with a Ca++ channel-associated binding site, when delivered (30 to 150 micrograms/kg) intra-arterially (ia) to enflurane-anesthetized cats, produced a dose-dependent suppression of seizures evoked by pentylenetetrazol."3.67Effect of dihydropyridines and diphenylalkylamines on pentylenetetrazol-induced seizures and cerebral blood flow in cats. ( Anderson, RE; Ots, ME; Sundt, TM; Yaksh, TL, 1987)
" We report herein the influence of nimodipine, a selective central nervous system calcium channel blocker, in 60 rabbits with seizures that had been induced through ischemia, postischemia reperfusion, pentylenetetrazol, and bicuculline."3.67Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents. ( Anderson, RE; Meyer, FB; Sharbrough, FW; Sundt, TM, 1986)
" Two patients with mild symptoms were rechallenged with a lower verapamil dosage (120 mg twice a day) and showed similar rises in CBZ concentration and recurrent neurotoxic symptoms."2.66Verapamil potentiates carbamazepine neurotoxicity: a clinically important inhibitory interaction. ( Brodie, MJ; Macphee, GJ; McInnes, GT; Thompson, GG, 1986)
"Soon thereafter, the patient had a seizure; he required intubation, developed cardiac conduction abnormalities, and became hypotensive."2.38Verapamil overdose: case report and review of the literature. ( Crain, JL; Edwards, TD; Stiller, RA; Watling, SM, 1992)
"2 of the patients (10%) had <50% seizure reduction."1.43Low dose verapamil as an adjunct therapy for medically refractory epilepsy - An open label pilot study. ( Frech, R; Frigerio, R; Maraganore, DM; Narayanan, J; Patel, V; Walters, S, 2016)
"At least, part of antiseizure effects of cannabinoid compounds is mediated through calcium (Ca(2+)) channels."1.38L-type calcium channel mediates anticonvulsant effect of cannabinoids in acute and chronic murine models of seizure. ( Ahmad-Molaei, L; Eslahkar, S; Mazar-Atabaki, A; Motiei-Langroudi, SM; Naderi, N; Ronaghi, A; Shirazi-zand, Z, 2012)
"To reveal putative seizure-induced changes in blood-brain barrier integrity, we performed gadolinium-enhanced magnetic resonance scans on a 7."1.37A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier. ( Bankstahl, JP; Bankstahl, M; Ding, XQ; Kuntner, C; Langer, O; Löscher, W; Meier, M; Müller, M; Stanek, J; Wanek, T, 2011)
"We report a case of familial hemiplegic migraine with prolonged aura where multimodality imaging showed hemispheric cytotoxic edema along with evidence of hypometabolism in the affected hemisphere while there was no evidence of hypoperfusion of the affected hemisphere demonstrating that neuronal depression is a more plausible explanation in its pathogenesis."1.35Familial hemiplegic migraine with prolonged aura and multimodality imaging: a case report. ( Kumar, G; Maytal, J; Topper, L, 2009)
"Flunarizine was also the only drug that antagonized methamphetamine-induced stereotypy."1.29Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats. ( Calder, L; Clikeman, J; Finnegan, KT; Karler, R; Wei, S, 1993)
"The patient developed coma, seizures, respiratory depression, bradycardia, and hypotension."1.27Verapamil poisoning in an infant. ( Crespin, FH; Passal, DB, 1984)
"Verapamil significantly decreased seizure incidence and both it and flunarizine lowered mortality."1.27Calcium channel antagonists decrease the ethanol withdrawal syndrome. ( Dolin, SJ; Halsey, MJ; Little, HJ, 1986)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199018 (43.90)18.7374
1990's7 (17.07)18.2507
2000's5 (12.20)29.6817
2010's10 (24.39)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Mao, G1
Gigliotti, MJ1
Esplin, N1
Sexton, K1
Antunes, NJ1
van Dijkman, SC1
Lanchote, VL1
Wichert-Ana, L1
Coelho, EB1
Alexandre Junior, V1
Takayanagui, OM1
Tozatto, E1
van Hasselt, JGC1
Della Pasqua, O1
Zhang, C1
Fan, Q1
Chen, SL1
Ma, H1
Bonnet, U1
Wiemann, M1
Narayanan, J1
Frech, R1
Walters, S1
Patel, V1
Frigerio, R1
Maraganore, DM1
Kumar, G1
Topper, L1
Maytal, J1
Fletcher, JJ1
Kramer, AH1
Bleck, TP1
Solenski, NJ1
Sawatzki, M1
Kummer, O1
Krähenbühl, S1
Siegemund, M1
Chatterjee, N1
Domoto-Reilly, K1
Fecci, PE1
Schwamm, LH1
Singhal, AB1
Luna-Munguia, H1
Orozco-Suarez, S1
Rocha, L1
Bankstahl, JP1
Bankstahl, M1
Kuntner, C1
Stanek, J1
Wanek, T1
Meier, M1
Ding, XQ1
Müller, M1
Langer, O1
Löscher, W1
Naderi, N1
Ahmad-Molaei, L1
Mazar-Atabaki, A1
Ronaghi, A1
Shirazi-zand, Z1
Motiei-Langroudi, SM1
Eslahkar, S1
Rahme, R1
Abruzzo, TA1
Zuccarello, M1
Ringer, A1
Wajima, Z1
Yoshikawa, T1
Ogura, A1
Imanaga, K1
Shiga, T1
Inoue, T1
Ogawa, R1
Westhout, FD1
Nwagwu, CI1
Luszczki, JJ1
Trojnar, MK1
Trojnar, MP1
Kimber-Trojnar, Z1
Szostakiewicz, B1
Zadrozniak, A1
Borowicz, KK1
Czuczwar, SJ2
Passal, DB1
Crespin, FH1
Greenberg, A1
Piraino, BH1
Kroboth, PD1
Weiss, J1
Kovách, AG2
Dóra, E2
Szedlacsek, S1
Koller, A1
Finnegan, KT1
Calder, L1
Clikeman, J1
Wei, S1
Karler, R1
Lazarova, M1
Petkova, B1
Staneva-Stoycheva, D1
De Sarro, GB1
De Sarro, A1
Trimarchi, GR1
Nistico', G1
Watling, SM1
Crain, JL1
Edwards, TD1
Stiller, RA1
Bahls, FH1
Ozuna, J1
Ritchie, DE1
Małek, U1
Kleinrok, Z1
Straub, H1
Speckmann, EJ4
Bingmann, D3
Walden, J2
Meyer, FB2
Tally, PW1
Anderson, RE3
Sundt, TM3
Yaksh, TL2
Sharbrough, FW2
Hendren, WG1
Schieber, RS1
Garrettson, LK1
Derlet, RW1
Albertson, TE1
Macphee, GJ1
McInnes, GT1
Thompson, GG1
Brodie, MJ1
Baker, RE1
Ruijter, J1
de Jong, BM1
Beattie, B1
Biller, J1
Mehlhaus, B1
Murray, M1
Papp, A1
Fehér, O1
Erdélyi, L1
Ots, ME1
Little, HJ1
Dolin, SJ1
Halsey, MJ1
Weinbroum, A1
Heifetz, M1
Bursztein, S1
Filias, N1
Jornod, J1

Reviews

2 reviews available for verapamil and Absence Seizure

ArticleYear
Verapamil overdose: case report and review of the literature.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:11

    Topics: Adolescent; Cardiac Pacing, Artificial; Charcoal; Drug Overdose; Fluid Therapy; Gastric Lavage; Hear

1992
Extracorporeal bypass for the treatment of verapamil poisoning.
    Annals of emergency medicine, 1989, Volume: 18, Issue:9

    Topics: Cardiopulmonary Bypass; Child, Preschool; Combined Modality Therapy; Delayed-Action Preparations; Hu

1989

Trials

3 trials available for verapamil and Absence Seizure

ArticleYear
Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Nov-15, Volume: 109S

    Topics: Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availabi

2017
Intravenous verapamil blunts hyperdynamic responses during electroconvulsive therapy without altering seizure activity.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:2

    Topics: Adult; Aged; Anesthesia; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind

2002
Verapamil potentiates carbamazepine neurotoxicity: a clinically important inhibitory interaction.
    Lancet (London, England), 1986, Mar-29, Volume: 1, Issue:8483

    Topics: Adult; Carbamazepine; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Synergism; Drug

1986

Other Studies

36 other studies available for verapamil and Absence Seizure

ArticleYear
The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
    Clinical neurology and neurosurgery, 2021, Volume: 202

    Topics: Aneurysm, Ruptured; Anticonvulsants; Brain Ischemia; Dose-Response Relationship, Drug; Female; Funct

2021
Reversal of P-glycoprotein overexpression by Ginkgo biloba extract in the brains of pentylenetetrazole-kindled and phenytoin-treated mice.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caspase 3; Disease Models,

2015
Verapamil and ethacrynic acid are associated with neuronal acidification in hippocampal CA3-neurons (slice preparation, guinea pig): Contribution to their anti-seizure potency?
    Pharmacological research, 2016, Volume: 110

    Topics: Animals; Anticonvulsants; CA3 Region, Hippocampal; Ethacrynic Acid; Guinea Pigs; Hydrogen-Ion Concen

2016
Low dose verapamil as an adjunct therapy for medically refractory epilepsy - An open label pilot study.
    Epilepsy research, 2016, Volume: 126

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Chemotherapy, Adjuvant; Drug Resistant Epilepsy; Female; H

2016
Familial hemiplegic migraine with prolonged aura and multimodality imaging: a case report.
    Headache, 2009, Volume: 49, Issue:1

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Child; Electroencephalography; Female; Humans; Magnetic Re

2009
Overlapping features of eclampsia and postpartum angiopathy.
    Neurocritical care, 2009, Volume: 11, Issue:2

    Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipi

2009
[Seizure and non-cardiogenic pulmonary edema after intoxication].
    Der Internist, 2010, Volume: 51, Issue:4

    Topics: Adult; Cardiovascular Diseases; Diagnosis, Differential; Female; Humans; Pulmonary Edema; Seizures;

2010
Licorice-associated reversible cerebral vasoconstriction with PRES.
    Neurology, 2010, Nov-23, Volume: 75, Issue:21

    Topics: Administration, Oral; Brain; Cerebral Angiography; Cerebrovascular Circulation; Cerebrovascular Diso

2010
Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures.
    Neuropharmacology, 2011, Volume: 61, Issue:4

    Topics: Animals; Disease Models, Animal; Disease Susceptibility; Drug Resistance; Electric Stimulation; Extr

2011
A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jun-15, Volume: 31, Issue:24

    Topics: Analysis of Variance; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Memb

2011
L-type calcium channel mediates anticonvulsant effect of cannabinoids in acute and chronic murine models of seizure.
    Neurochemical research, 2012, Volume: 37, Issue:2

    Topics: Acute Disease; Animals; Anticonvulsants; Benzamides; Benzoxazines; Calcium Channels, L-Type; Cannabi

2012
Intra-arterial veramil-induced seizures: drug toxicity or rapid reperfusion?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2012, Volume: 39, Issue:4

    Topics: Accidents, Traffic; Adult; Anti-Arrhythmia Agents; Cerebral Angiography; Craniocerebral Trauma; Fema

2012
Intra-arterial verapamil-induced seizures: case report and review of the literature.
    Surgical neurology, 2007, Volume: 67, Issue:5

    Topics: Adult; Anticonvulsants; Aphasia, Broca; Carotid Artery, Internal; Female; Functional Laterality; Hum

2007
Effects of amlodipine, diltiazem, and verapamil on the anticonvulsant action of topiramate against maximal electroshock-induced seizures in mice.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:3

    Topics: Amlodipine; Animals; Anticonvulsants; Behavior, Animal; Brain; Calcium Channel Blockers; Diltiazem;

2008
Verapamil poisoning in an infant.
    Pediatrics, 1984, Volume: 73, Issue:4

    Topics: Bradycardia; Calcium Chloride; Coma; Female; Humans; Hypotension; Infant; Respiratory Insufficiency;

1984
Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion.
    The American journal of medicine, 1984, Volume: 76, Issue:5

    Topics: Aged; Heart Rate; Hemoperfusion; Humans; Hypotension; Kinetics; Male; Middle Aged; Propranolol; Seiz

1984
Contribution of adenosine to the regulation of cerebral blood flow: the role of calcium ions in the adenosine-induced cerebrocortical vasodilatation.
    Advances in experimental medicine and biology, 1984, Volume: 169

    Topics: Adenosine; Animals; Calcium; Calcium Channel Blockers; Cats; Cerebral Cortex; Cerebrovascular Circul

1984
Effect of the organic calcium antagonist D-600 on cerebrocortical vascular and redox responses evoked by adenosine, anoxia, and epilepsy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1983, Volume: 3, Issue:1

    Topics: Adenosine; Animals; Blood Volume; Cats; Cerebral Cortex; Cerebrovascular Circulation; Electrocardiog

1983
Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Calcium Channel Blockers; Cerebral Cortex;

1993
Effects of the calcium antagonists verapamil and nitrendipine on carbamazepine withdrawal.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:10

    Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Convulsants; Male; Nitrendipine;

1999
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin.
    Neurology, 1991, Volume: 41, Issue:5

    Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Carbamazepine; Diltiazem; Drug Interactions; Female

1991
Influence of calcium channel inhibitors upon the anticonvulsant efficacy of common antiepileptics against pentylenetetrazol-induced convulsions in mice.
    Neuropharmacology, 1990, Volume: 29, Issue:10

    Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Ethosuximi

1990
Paroxysmal depolarization shifts induced by bicuculline in CA3 neurons of hippocampal slices: suppression by the organic calcium antagonist verapamil.
    Neuroscience letters, 1990, Mar-26, Volume: 111, Issue:1-2

    Topics: Animals; Bicuculline; Guinea Pigs; Hippocampus; In Vitro Techniques; Seizures; Verapamil

1990
Inhibition of electrically induced seizures by a dihydropyridine calcium channel blocker.
    Brain research, 1986, Oct-01, Volume: 384, Issue:1

    Topics: Animals; Catheterization; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; I

1986
Suppression of recurrent generalized tonic-clonic seizure discharges by intraventricular perfusion of a calcium antagonist.
    Electroencephalography and clinical neurophysiology, 1988, Volume: 69, Issue:4

    Topics: Animals; Pentylenetetrazole; Rats; Recurrence; Seizures; Verapamil

1988
Potentiation of cocaine toxicity with calcium channel blockers.
    The American journal of emergency medicine, 1989, Volume: 7, Issue:5

    Topics: Animals; Cocaine; Diltiazem; Drug Synergism; Injections, Intraperitoneal; Male; Nifedipine; Rats; Ra

1989
Specific suppression of pentylenetetrazol-induced epileptiform discharges in CA3 neurons (hippocampal slice, guinea pig) by the organic calcium antagonists flunarizine and verapamil.
    Experimental brain research, 1989, Volume: 74, Issue:2

    Topics: Animals; Flunarizine; Guinea Pigs; Hippocampus; In Vitro Techniques; Pentylenetetrazole; Seizures; V

1989
Differential antiepileptic effects of the organic calcium antagonists verapamil and flunarizine in neurons of organotypic neocortical explants from newborn rats.
    Experimental brain research, 1988, Volume: 72, Issue:2

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Flunarizine; Membrane Potentials; Neurons; Organ Culture

1988
Verapamil-induced carbamazepine neurotoxicity. A report of two cases.
    European neurology, 1988, Volume: 28, Issue:2

    Topics: Adult; Ataxia; Carbamazepine; Drug Interactions; Female; Humans; Middle Aged; Seizures; Verapamil

1988
The ionic mechanism of the pentylenetetrazol convulsions.
    Acta biologica Hungarica, 1987, Volume: 38, Issue:3-4

    Topics: Animals; Cobalt; Electrophysiology; Helix, Snails; Ions; Manganese; Nickel; Pentylenetetrazole; Seiz

1987
Effect of dihydropyridines and diphenylalkylamines on pentylenetetrazol-induced seizures and cerebral blood flow in cats.
    Journal of neurosurgery, 1987, Volume: 67, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cats; Cerebrovascular Circulation; Clonaz

1987
Calcium channel antagonists decrease the ethanol withdrawal syndrome.
    Life sciences, 1986, Dec-01, Volume: 39, Issue:22

    Topics: Animals; Calcium Channel Blockers; Diazepam; Ethanol; Flunarizine; Male; Motor Activity; Nimodipine;

1986
Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents.
    Mayo Clinic proceedings, 1986, Volume: 61, Issue:4

    Topics: Animals; Anticonvulsants; Bicuculline; Calcium Channel Blockers; Central Nervous System; Convulsants

1986
[Poisoning by tricyclic antidepressants and antidotes].
    Harefuah, 1985, Volume: 109, Issue:5-6

    Topics: Adolescent; Amitriptyline; Female; Humans; Phenytoin; Physostigmine; Seizures; Suicide, Attempted; T

1985
[Cardiovascular complications of tricyclic anti-depressants. Apropos of a case of acute poisoning].
    Revue medicale de la Suisse romande, 1973, Volume: 93, Issue:12

    Topics: Adult; Arrhythmias, Cardiac; Bundle-Branch Block; Diazepam; Digitalis Glycosides; Electrocardiograph

1973