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verapamil and Abnormalities, Drug-Induced

verapamil has been researched along with Abnormalities, Drug-Induced in 5 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
" In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis."3.80Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cullinane, J1
Bannigan, J1
Thompson, J1
Zhu, JJ1
Xu, YQ1
He, JH1
Yu, HP1
Huang, CJ1
Gao, JM1
Dong, QX1
Xuan, YX1
Li, CQ1
Bílá, V1
Kren, V1
Burgess, AM1
Vere, DW1
Nishikawa, T1
Kajita, A1
Ando, M1
Takao, A1
Bruyere, HJ1
Gilbert, EF1

Other Studies

5 other studies available for verapamil and Abnormalities, Drug-Induced

ArticleYear
Cadmium teratogenesis in the chick: period of vulnerability using the early chick culture method, and prevention by divalent cations.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Calcium; Calcium Channel Blockers; Cations, Divalent; Chick Em

2009
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease

2014
Teratogenicity testing based on the interaction with a mutant allele.
    Folia biologica, 1992, Volume: 38, Issue:1

    Topics: Abnormalities, Drug-Induced; Alleles; Animals; Anti-Bacterial Agents; Cyclophosphamide; Female; Fetu

1992
Teratogenic effects of some calcium channel blocking agents in Xenopus embryos.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Calcium Channel Blockers; Diltiazem; Nicardipine; Verapamil; X

1989
Potentiating effects of verapamil on cardiovascular teratogenicity of phenobarbital in the chick embryos.
    Developmental pharmacology and therapeutics, 1988, Volume: 11, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Aorta; Calcium; Chick Embryo; Drug Synergism; Heart Defects, C

1988