verapamil has been researched along with Abnormalities, Autosome in 11 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These lymphocytes showed higher chromosomal aberrations in comparison with lymphocytes isolated from the patients before treatment." | 1.28 | Ca antagonist verapamil and tumor promoter 12-O-tetradecanoylphorbol-13- acetate (TPA) induce chromosomal aberrations in human lymphocytes. ( Baharav, E; Friedman, J; Halbrecht, I; Sandowski, U; Shabtai, F, 1990) |
| "The induction of 2-break chromosome aberrations (dicentrics and ring chromosomes) in human lymphocytes by the antitumor agents bleomycin and peplomycin is strongly enhanced when those agents are applied together with the heart drug verapamil (isoptin)." | 1.27 | The cytogenetic efficiency of the antitumor agents bleomycin and peplomycin is enhanced by the heart drug verapamil (isoptin). ( Oppermann, B; Scheid, W; Traut, H, 1984) |
| "Fetal cardiac arrhythmias are usually first suspected on the basis of auscultatory findings during routine examination in pregnancy." | 1.27 | Treatment of fetal cardiac arrhythmias. ( Stewart, PA; Wladimiroff, JW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dyomina, EA | 1 |
| Pylypchuk, OP | 1 |
| el-Ashmawy, IM | 1 |
| el-Nahas, AF | 1 |
| Bayad, AE | 1 |
| McDonald, SL | 1 |
| Stevenson, DA | 1 |
| Moir, SE | 1 |
| Hutcheon, AW | 1 |
| Haites, NE | 1 |
| Heys, SD | 1 |
| Schofield, AC | 1 |
| Scheid, W | 2 |
| Oppermann, B | 1 |
| Traut, H | 2 |
| Liu, YC | 1 |
| Huang, H | 1 |
| Nesterova, EV | 2 |
| Durnev, AD | 2 |
| Seredenin, SB | 2 |
| Redner, A | 1 |
| Hegewisch, S | 1 |
| Haimi, J | 1 |
| Steinherz, P | 1 |
| Jhanwar, S | 1 |
| Andreeff, M | 1 |
| Friedman, J | 1 |
| Shabtai, F | 1 |
| Sandowski, U | 1 |
| Baharav, E | 1 |
| Halbrecht, I | 1 |
| Wladimiroff, JW | 1 |
| Stewart, PA | 1 |
11 other studies available for verapamil and Abnormalities, Autosome
| Article | Year |
|---|---|
Formation peculiarities of radiation-induced aberrations of chromosomes in human cells under the modifying influence of chemical agents (comparative aspects).
Topics: Cells, Cultured; Chromatids; Chromosome Aberrations; Dose-Response Relationship, Radiation; Gamma Ra | 2013 |
Teratogenic and cytogenetic effects of ivermectin and its interaction with P-glycoprotein inhibitor.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B; Bone Marrow; Bone Marrow Cell | 2011 |
Genomic changes identified by comparative genomic hybridisation in docetaxel-resistant breast cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast N | 2005 |
The cytogenetic efficiency of the antitumor agents bleomycin and peplomycin is enhanced by the heart drug verapamil (isoptin).
Topics: Bleomycin; Cells, Cultured; Chromosome Aberrations; Drug Interactions; Female; Humans; Peplomycin; V | 1984 |
Involvement of calcium-dependent protein kinase C in arsenite-induced genotoxicity in Chinese hamster ovary cells.
Topics: Adenosine Triphosphate; Animals; Arsenates; Calcium; Catalase; CHO Cells; Chromosome Aberrations; Cr | 1997 |
Verapamil contributes to the clastogenic effects of acrylamide, cyclophosphamide, and dioxidine on somatic cells of BALB/C and C57BL/6 mice.
Topics: Acrylamide; Animals; Bone Marrow Cells; Calcium Channel Blockers; Chromosome Aberrations; Cyclophosp | 1999 |
[Cytogenetic effects of acrylamide, acrylonitrile and their combination with verapamil in vivo].
Topics: Acrylamide; Acrylonitrile; Animals; Chromosome Aberrations; Drug Synergism; Male; Mice; Mice, Inbred | 1999 |
A study of multidrug resistance and cell kinetics in a child with near-haploid acute lymphoblastic leukemia.
Topics: Cell Cycle; Chromosome Aberrations; Daunorubicin; Drug Resistance; Haplotypes; Humans; Membrane Glyc | 1990 |
Ca antagonist verapamil and tumor promoter 12-O-tetradecanoylphorbol-13- acetate (TPA) induce chromosomal aberrations in human lymphocytes.
Topics: Chromosome Aberrations; Humans; Lymphocytes; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Synergistic enhancement of the bleomycin and peplomycin induced mitotic index reduction by verapamil.
Topics: Adult; Bleomycin; Cell Survival; Chromosome Aberrations; Drug Synergism; Female; Humans; In Vitro Te | 1985 |
Treatment of fetal cardiac arrhythmias.
Topics: Amiodarone; Arrhythmia, Sinus; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; D | 1985 |