Page last updated: 2024-11-05
venlafaxine and Pain
venlafaxine has been researched along with Pain in 2 studies
venlafaxine : A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Synthesis and testing of a series of cyclohexanol ethylpiperazines identified ( S)-(-)- 17i (WAY-256805), a potent norepinephrine reuptake inhibitor (IC 50 = 82 nM, K i = 50 nM) that exhibited excellent selectivity over both the serotonin and dopamine transporters and was efficacious in animal models of depression, pain, and thermoregulatory dysfunction." | 3.74 | Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors. ( Belardi, JK; Bray, JA; Burroughs, KD; Cohn, ST; Cosmi, SA; Deecher, DC; Gavrin, LK; Ho, DM; Johnston, GH; Koury, EJ; Leiter, J; Leventhal, L; Mahaney, PE; Mugford, CA; Platt, B; Rosenzweig-Lipson, SJ; Sabatucci, JP; Santilli, AA; Smith, VA; Stack, GP; Trybulski, EJ; Vu, TA; Ye, F; Zhang, Y, 2008) |
| "A series of mutual prodrugs derived from gabapentin, pregabalin, memantine, venlafaxine were synthesized and their pharmacological properties to treat neuropathic pain were investigated in a rat model of chronic sciatic nerve constriction injury (CCI)." | 3.72 | Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury. ( Bo-Hua, Z; He, L; Hong-Ju, Y; Jun-Wei, W; Nan, Z; Wei-Guo, S; Wei-Xiu, Y; Zhe-Hui, G; Zheng-Hua, G; Zhi-Pu, L; Zhong-Wei, J, 2004) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hong-Ju, Y | 1 |
| He, L | 1 |
| Wei-Guo, S | 1 |
| Nan, Z | 1 |
| Wei-Xiu, Y | 1 |
| Zhong-Wei, J | 1 |
| Jun-Wei, W | 1 |
| Zheng-Hua, G | 1 |
| Bo-Hua, Z | 1 |
| Zhi-Pu, L | 1 |
| Zhe-Hui, G | 1 |
| Mahaney, PE | 1 |
| Gavrin, LK | 1 |
| Trybulski, EJ | 1 |
| Stack, GP | 1 |
| Vu, TA | 1 |
| Cohn, ST | 1 |
| Ye, F | 1 |
| Belardi, JK | 1 |
| Santilli, AA | 1 |
| Sabatucci, JP | 1 |
| Leiter, J | 1 |
| Johnston, GH | 1 |
| Bray, JA | 1 |
| Burroughs, KD | 1 |
| Cosmi, SA | 1 |
| Leventhal, L | 1 |
| Koury, EJ | 1 |
| Zhang, Y | 1 |
| Mugford, CA | 1 |
| Ho, DM | 1 |
| Rosenzweig-Lipson, SJ | 1 |
| Platt, B | 1 |
| Smith, VA | 1 |
| Deecher, DC | 1 |
Other Studies
2 other studies available for venlafaxine and Pain
| Article | Year |
|---|---|
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
Topics: Amines; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal | 2004 |
Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.
Topics: Animals; Cell Line; Cyclohexanols; Ethylamines; Female; Humans; Male; Mice; Models, Molecular; Molec | 2008 |