vendex has been researched along with Staphylococcal-Infections* in 2 studies
2 other study(ies) available for vendex and Staphylococcal-Infections
Article | Year |
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Fluid accumulation and the rapid spread of bacteria in the pathogenesis of external fixator pin track infection.
An animal model was used to study the pathogenesis of pin track infection. The roles of fluid accumulation around the pin/bone interface and mechanical loosening of the pin were specifically studied. In addition, the spread of bacteria in relation to the clinical appearance of the pin track was assessed. This study demonstrated that fluid accumulation around the interface is an important factor in the spread of infection from the superficial wound track to the medulla of the bone. Spread occurs despite the absence of mechanical pin loosening, and can occur before any clinical features of infection are apparent. Topics: Animals; Body Fluids; Bone Nails; Female; Fracture Fixation; Models, Animal; Prosthesis-Related Infections; Sheep; Staphylococcal Infections; Torque | 2001 |
Antimicrobial efficacy of external fixator pins coated with a lipid stabilized hydroxyapatite/chlorhexidine complex to prevent pin tract infection in a goat model.
Pin tract infection is a common complication of external fixation. An antiinfective external fixator pin might help to reduce the incidence of pin tract infection and improve pin fixation.. Stainless steel and titanium external fixator pins, with and without a lipid stabilized hydroxyapatite/chlorhexidine coating, were evaluated in a goat model. Two pins contaminated with an identifiable Staphylococcus aureus strain were inserted into each tibia of 12 goats. The pin sites were examined daily. On day 14, the animals were killed, and the pin tips cultured. Insertion and extraction torques were measured.. Infection developed in 100% of uncoated pins, whereas coated pins demonstrated 4.2% infected, 12.5% colonized, and the remainder, 83.3%, had no growth (p < 0.01). Pin coating decreased the percent loss of fixation torque over uncoated pins (p = 0.04).. These results demonstrate that the lipid stabilized hydroxyapatite/chlorhexidine coating was successful in decreasing infection and improving fixation of external fixator pins. Topics: Animals; Anti-Infective Agents, Local; Bone Nails; Chi-Square Distribution; Chlorhexidine; Coated Materials, Biocompatible; Device Removal; Disease Models, Animal; Durapatite; External Fixators; Fracture Fixation; Goats; Male; Stainless Steel; Staphylococcal Infections; Statistics, Nonparametric; Tibial Fractures; Titanium; Torque | 2001 |