vendex and Periodontal-Pocket

The purpose of this ongoing randomized study was to assess differences in bone level changes and success rates using implants supporting single crowns in the posterior mandible either with platform matched or platform switched abutments.. Patients aged 18 and above, missing at least two teeth in the posterior mandible and with a natural tooth mesial to the most proximal implant site were enrolled. Randomization followed implant placement. Definitive restorations were placed after a minimum transgingival healing period of 8 weeks. Changes in crestal bone level from surgery and loading (baseline) to 12-month post-loading were radiographically measured. Implant survival and success were determined.. Sixty-eight patients received 74 implants in the platform switching group and 72 in the other one. The difference of mean marginal bone level change from surgery to 12 months was significant between groups (p < 0.004). Radiographical mean bone gain or no bone loss from loading was noted for 67.1% of the platform switching and 49.2% of the platform matching implants. Implant success rates were 97.3% and 100%, respectively.. Within the same implant system the platform switching concept showed a positive effect on marginal bone levels when compared with restorations with platform matching.

Topics: Alveolar Process; Bone Density; Bone Remodeling; Cementation; Crowns; Dental Implant-Abutment Design; Dental Implants, Single-Tooth; Dental Plaque Index; Dental Prosthesis, Implant-Supported; Dental Restoration Failure; Female; Follow-Up Studies; Humans; Male; Mandible; Middle Aged; Periodontal Index; Periodontal Pocket; Prospective Studies; Radiography, Bitewing; Survival Analysis; Torque; Treatment Outcome

To compare the clinical outcome of platform switching (PS) and regular platform (RP) implants in bilateral single molar replacements.. This study was designed as a randomised, controlled, split-mouth trial. Eighteen patients, with bilaterally missing single molars had one site randomly assigned to a PS implant or a RP implant. A total of 36 implants were bilaterally installed. Both implants were loaded with screw retained temporary crowns 3 months after implant insertion and with screw retained definitive crowns 3 months later. Outcome measures were implant/crown failure, complications, radiographic marginal bone-level changes, pocket probing depth (PPD) and bleeding on probing (BOP). Clinical data were collected at baseline 6 and 12 months after implant placement.. No patients dropped out and no implant failed. No prosthetic or major biological complications were observed. One year after implant placement, mean marginal bone level was 0.93 ± 0.26 mm (95% CI 0.81 to 1.05) in RP group and 0.84 ± 0.23 mm (95% CI 0.73 to 0.95) in the PS group and no statistically significant differences between the two groups were observed (P = 0.18). Mean PPD and BOP values were, 6 and 12 months after implant placement, 2.74 ± 0.49 mm (95% CI 2.51 to 2.97) and 1.28 ± 0.75 (95% CI 0.93 to 1.63) in the RP group, and 2.70 ± 0.38 mm (95% CI 2.53 to 2.88) and 1.39 ± 0.78 (95% CI 1.03 to 1.75) in the PS group respectively, with no statistical differences between groups (P = 0.81 and P = 0.16, respectively).. No statistically significant difference was observed between platform switched and non-platform switched implants.

Topics: Adult; Aged; Alveolar Bone Loss; Alveolar Process; Crowns; Dental Implant-Abutment Design; Dental Implants, Single-Tooth; Dental Restoration Failure; Female; Follow-Up Studies; Gingival Hemorrhage; Humans; Male; Middle Aged; Osseointegration; Periodontal Pocket; Radiography, Dental, Digital; Torque; Treatment Outcome

Whilst there is keen interest in developing improved drug delivery devices to the periodontal pocket and oral mucosa, there are few reports which have examined the physical properties of gels and semi-solid formulations which favour retention and bioadhesion in situ. Hydration and rheological properties appear to be of prime importance in this context and this study aimed to correlate the measurement of these properties with observed bioadhesion, both in vitro and in vivo. Three candidate bioadhesives were selected from previous experiments which had used in vitro organ culture models. These were chitosan, xanthan gum and poly (ethylene oxide) aqueous formulations. Hydration rates with various media were determined in specially constructed cells. Rheological properties were measured using a controlled stress rheometer under carefully regulated conditions. These findings were also correlated with in vivo assessments in the periodontal pocket and oral mucosa. The results demonstrated that three formulations with differing bioadhesive properties also possessed widely different physical characteristics. Hydration experiments indicated a direct relationship between the rate of hydration and bioadhesion or retention. Rheological studies suggested that possession of a gel structure could be an important determinant of retention where shear displacing forces are present in vivo, e.g. the oral mucosa. Furthermore, these studies indicated that formulations which could demonstrate resistance to changes in rheological properties on hydration would also favour retention in situ. Physical characterisation therefore appears to have an important place in screening polymeric formulations prior to clinical testing in the periodontal pocket and oral mucosa.

Topics: Adhesiveness; Adhesives; Administration, Buccal; Biocompatible Materials; Biopolymers; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chitin; Chitosan; Drug Carriers; Drug Delivery Systems; Elasticity; Fluoresceins; Fluorescent Dyes; Gels; Humans; Materials Testing; Mouth Mucosa; Organ Culture Techniques; Periodontal Pocket; Polyethylene Glycols; Polysaccharides, Bacterial; Rheology; Stress, Mechanical; Surface-Active Agents; Torque; Water