vendex and Diabetes-Mellitus

Diabetes leads to numerous side effects, including an increased density of collagen fibrils and thickening of the Achilles tendon. This may increase tissue stiffness and could affect stretch distribution between muscle and tendinous tissues during walking. The primary aim of this study was to examine stretch distribution between muscle and tendinous tissues in the medial gastrocnemius muscle-tendon unit in long-term diabetes patients and control subjects during walking.. Achilles tendon length changes were investigated in 13 non-neuropathic diabetes patients and 12 controls, whilst walking at a self selected speed across a 10 m force platform. Electromyographic activity was recorded in the medial gastrocnemius, soleus and tibialis anterior muscles, goniometers were used to detect joint angle changes, and ultrasound was used to estimate tendon length changes.. Achilles tendon length changes were attenuated in diabetes patients compared to controls, and were inversely correlated with diabetes duration (r=-0.628; P<0.05), as was ankle range of motion (r=-0.693; P<0.01). Tendon length changes were also independent of walking speed (r=-0.299; P=0.224) and age (r=0.115; P=0.721) in the diabetic group.. Stretch distribution between muscle and tendon during walking is altered in diabetic patients, which could decrease walking efficiency, a factor that may be exacerbated with increasing diabetes duration. Diabetes-induced changes in mechanical tendon properties may be at least partly responsible for attenuated tendon length changes during walking in this patient group.

Topics: Achilles Tendon; Biomechanical Phenomena; Case-Control Studies; Diabetes Mellitus; Electromyography; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Statistics, Nonparametric; Torque; Ultrasonography; Walking

Portable, custom-made electronic dynamometry for the foot and ankle is a promising assessment method that enables foot and ankle muscle function to be established in healthy participants and those affected by chronic conditions. Diabetic peripheral neuropathy (DPN) can alter foot and ankle muscle function. This study assessed ankle toque in participants with diabetic peripheral neuropathy and healthy participants, with the aim of developing an algorithm for optimizing the precision of data processing and interpretation of the results and to define a reference frame for ankle torque measurement in both healthy participants and those affected by DPN. This paper discloses the software chain and the signal processing methods used for voltage-torque conversion, filtering, offset detection and the muscle effort type identification, which further allowed for a primary statistical report. The full description of the signal processing methods will make our research reproducible. The applied algorithm for signal processing is proposed as a reference frame for ankle torque assessment when using a custom-made electronic dynamometer. While evaluating multiple measurements, our algorithm permits for a more detailed parametrization of the ankle torque results in healthy participants and those affected by DPN.

Topics: Ankle; Ankle Joint; Diabetes Mellitus; Diabetic Neuropathies; Electronics; Humans; Muscle Strength; Muscle, Skeletal; Torque

The aim of the study was to determine the effect of comorbidities on physical function and quality of life of patients at 3 mos after total knee arthroplasty.. Data from 140 patients who underwent a primary unilateral total knee arthroplasty were examined retrospectively. Comorbidities were osteoporosis, presarcopenia, degenerative spine disease, diabetes, and hypertension. All patients completed the following: range of motion, stair climbing test, 6-min walk test, Timed Up and Go Test, peak torque of the knee extensor and flexor, instrumental gait analysis, Western Ontario McMaster Universities Osteoarthritis Index, and EuroQoL five-dimension questionnaire.. Univariate analyses revealed that osteoporosis led to a significantly longer time to complete the stair climbing test-ascent, stair climbing test-descent, and Timed Up and Go Test and to lower scores for the 6-min walk test and peak torque of the knee extensor. Patients with degenerative spine disease showed significant negative scores for knee extension range of motion. Diabetes showed a negative correlation with peak torque of the knee extensor and knee flexion range of motion, as well as a higher Western Ontario McMaster Universities Osteoarthritis Index-stiffness score. Multivariable linear regression analysis showed that Western Ontario McMaster Universities Osteoarthritis Index-stiffness remained independently associated with diabetes. Six-minute walk test, Timed Up and Go Test, stair climbing test-ascent, and peak torque of the knee extensors showed a significant association with osteoporosis.. Comorbidities, particularly osteoporosis and diabetes, affect short-term functional outcomes 3 mos after total knee arthroplasty.

Topics: Aged; Arthroplasty, Replacement, Knee; Comorbidity; Diabetes Mellitus; Disability Evaluation; Female; Gait Analysis; Humans; Hypertension; Knee Joint; Linear Models; Male; Osteoarthritis, Knee; Osteoporosis; Postoperative Period; Quality of Life; Range of Motion, Articular; Recovery of Function; Retrospective Studies; Sarcopenia; Spinal Diseases; Stair Climbing; Time and Motion Studies; Torque; Treatment Outcome; Walk Test

In this paper the torque of an oesophagus is studied for physiological and diabetic conditions. Since the function of the oesophagus is mainly mechanical, this work is focused on providing quantitative measurement of the passive biomechanical properties of the oesophagus torque. The oesophagus was treated as a membrane when calculating the stress and strain. The torque versus twist-angle relation was approximated to be linear at a specified pressure and longitudinal stretch ratio. Thus, the shear modulus can be computed by the torque, twist angle and polar moment of inertia in this state. The shear modulus varies greatly with the changing inflation pressure and longitudinal stretch ratio. When the longitudinal stretch ratio or transmural pressure is constant, the shear modulus is increased after 28 days of diabetes.

Topics: Animals; Biomechanical Phenomena; Diabetes Mellitus; Esophagus; Pressure; Rats; Rats, Wistar; Torque