venalot has been researched along with Xerostomia* in 1 studies
1 trial(s) available for venalot and Xerostomia
Article | Year |
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Prophylaxis of radiogenic sialadenitis and mucositis by coumarin/troxerutine in patients with head and neck cancer--a prospective,randomized, placebo-controlled, double-blind study.
To study the efficacy of coumarin/troxerutine for the protection of salivary glands and mucosa during irradiation.. Prospective, randomized, placebo-controlled, double-blind trial.. University hospital, Germany.. 48 patients who had radiotherapy to the head and neck.. Salivary gland scintigraphy and acute side-effects of radiotherapy (Radiation Therapy Oncology Group (RTOG) score).. 23 patients (11 experimental, 12 placebo) completed the study. The global efficacy measure combining scintigraphy and RTOG score favoured the experimental arm (P=0.07). The RTOG score showed significantly fewer acute side-effects of radiation in the experimental arm (P<0.05).. The results suggest that coumarin/troxerutine have a favourable effect in the treatment of radiogenic sialadenitis and mucositis. Topics: Adult; Aged; Coumarins; Cranial Irradiation; Double-Blind Method; Drug Combinations; Female; Head and Neck Neoplasms; Humans; Hydroxyethylrutoside; Male; Middle Aged; Mouth Mucosa; Prospective Studies; Radiation Injuries; Radiation-Protective Agents; Radionuclide Imaging; Radiopharmaceuticals; Salivary Glands; Sialadenitis; Sodium Pertechnetate Tc 99m; Treatment Outcome; Xerostomia | 2001 |