Page last updated: 2024-09-04

vatalanib and Glioma

vatalanib has been researched along with Glioma in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beumer, JH; Desjardins, A; Egorin, MJ; Friedman, HS; Gururangan, S; Herndon, JE; Lagattuta, TF; Reardon, DA; Salvado, AJ; Vredenburgh, JJ1
Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH1
Dai, C; Draghi, N; Eklöf, C; Holland, EC; Liang, X; Resh, MD; Uhrbom, L; Westermark, B; Wolf, RM1
Bendszus, M; Goldbrunner, RH; Kiderlen, M; Sasaki, M; Tonn, JC; Wood, J1

Trials

1 trial(s) available for vatalanib and Glioma

ArticleYear
Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma.
    Cancer, 2009, May-15, Volume: 115, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Hydroxyurea; Imatinib Mesylate; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Middle Aged; Phthalazines; Piperazines; Pyridines; Pyrimidines; Recurrence; Treatment Outcome

2009

Other Studies

3 other study(ies) available for vatalanib and Glioma

ArticleYear
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Glioma; Humans; Lactic Acid; Male; Neovascularization, Pathologic; Phthalazines; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyridines; Rats; Rats, Sprague-Dawley; Temozolomide; Treatment Outcome

2010
p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.
    Genes & development, 2003, Feb-15, Volume: 17, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Differentiation; Cells, Cultured; Chromosomes, Human, Pair 19; DNA-Binding Proteins; Down-Regulation; Genes, Tumor Suppressor; Glioma; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Humans; Intermediate Filament Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Nestin; Nuclear Proteins; Oligodendroglioma; Phthalazines; Platelet-Derived Growth Factor; Pyridines; Repressor Proteins; Retroviridae

2003
PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptor tyrosine kinases, decreases glioma growth and vascularization.
    Neurosurgery, 2004, Volume: 55, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Brain; Brain Neoplasms; Cell Division; Cell Survival; Glioma; Male; Neoplasm Transplantation; Neovascularization, Pathologic; Phthalazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2004