vatalanib has been researched along with Disease Models, Animal in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (59.09) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Aono, H; Ban, M; Honda, T; Inaba, T; Inoue, K; Kawashima, K; Okamoto, K; Sasabuchi, Y; Tajima, H; Takeno, Y; Yamamoto, M | 1 |
| Li, HL; Li, XL; Li, ZL; Liu, KC; Peng, WB; Wang, LY; Wang, X; Yang, DS; Yang, YP; Zhang, YL | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Bates, DO; Donaldson, LF; Drake, RA; Hulse, RP | 1 |
| Cordeiro, MM; Dong, Z; Miyazawa, M; Neiva, KG; Nör, JE; Oliveira, DT; Zhang, Z | 1 |
| Chen, Y; Fan, ST; Friedman, SL; Kok, TW; Li, L; Liu, Y; Lui, EL; Poon, RT; Wo, J; Ye, T | 1 |
| Augustin, HG; Dietz, CT; Epting, D; Feng, Y; Hammes, HP; Kern, K; Kroll, J; Wieland, T | 1 |
| Egashira, K; Kubo, M; Matoba, T; Nagahama, R; Nakano, K; Oda, S; Sunagawa, K; Tominaga, R | 1 |
| Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH | 1 |
| Böhm-Sturm, P; Diedenhofen, M; Hoehn, M; Jikeli, JF; Ullrich, RT; Unruh, M; Vollmar, S | 1 |
| Bali, S; Bhutta, MF; Brown, SD; Cheeseman, MT; Hilton, H; Hough, TA; Parker, A; Pathak, P; Potter, PK; Purnell, T; Romero, MR; Tyrer, HE; Vizor, L; Vowell, K; Wells, S; Williams, D | 1 |
| Li, G; Liang, S; Liu, H; Liu, S; Peng, H; Qiu, S; Tu, G; Xie, J; Xu, C | 1 |
| Bilenker, JH; Haller, DG | 1 |
| Holland, EC; Nerio, E; Uhrbom, L | 1 |
| Agostini, HT; Drevs, J; Hansen, LL; Junker, B; Maier, P; Martin, G; Unsoeld, AS | 1 |
| Ametamey, S; Honer, M; Jochum, W; Oehler, C; Pruschy, M; Riesterer, O | 1 |
| Arevalo, JM; Armaiz-Pena, G; Bankson, JA; Cole, SW; Coleman, RL; Felix, E; Gershenson, DM; Han, LY; Jennings, NB; Kamat, AA; Kim, TJ; Kundra, V; Landen, CN; Li, Y; Lin, YG; Lloyd, M; Lopez-Berestein, G; Lu, C; Lutgendorf, SK; Mangala, LS; Merritt, WM; Newman, RA; Ravoori, M; Sanguino, AM; Sood, AK; Takahashi, R; Thaker, PH | 1 |
| Bock, F; Cursiefen, C; Dietrich, T; Hos, D; Kruse, FE; Onderka, J; Thierauch, KH | 1 |
| Kallio, EA; Koskinen, PK; Lemström, KB; Malmström, NK; Nykänen, AI; Paavonen, T; Räisänen-Sokolowski, AK; Rintala, JM | 1 |
| Bold, G; Buchdunger, E; Cozens, R; Drevs, J; Ferrari, S; Frei, J; Hofmann, F; Martiny-Baron, G; Menrad, A; Mestan, J; Mett, H; O'Reilly, T; Persohn, E; Rösel, J; Schirner, M; Schneider, MR; Schnell, C; Siemeister, G; Stover, D; Theuer, A; Thierauch, KH; Totzke, F; Towbin, H; Wenger, F; Wood, JM; Woods-Cook, K | 1 |
| Drevs, J; Hofmann, I; Hugenschmidt, H; Madjar, H; Marmé, D; Martiny-Baron, G; Müller, M; Unger, C; Wittig, C; Wood, J | 1 |
| Aaltola, EM; Alitalo, K; Häyry, PJ; Koskinen, PK; Krebs, R; Lemström, KB; Nykänen, AI; Sihvola, RK; Tikkanen, JM; Wood, J; Ylä-Herttuala, S | 1 |
1 review(s) available for vatalanib and Disease Models, Animal
| Article | Year |
|---|---|
Future directions with angiogenesis inhibitors in colorectal cancer.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Colorectal Neoplasms; Disease Models, Animal; Drug Approval; Forecasting; Humans; Neovascularization, Pathologic; Phthalazines; Prognosis; Pyridines; Risk Assessment; Survival Analysis; Treatment Outcome; United States; United States Food and Drug Administration | 2004 |
21 other study(ies) available for vatalanib and Disease Models, Animal
| Article | Year |
|---|---|
Pyridylmethylthio derivatives as VEGF inhibitors. Part 1.
Topics: Anilides; Animals; Arthritis, Experimental; Cell Line; Choroidal Neovascularization; Disease Models, Animal; Endothelial Cells; Humans; Mice; Neoplasms; Pyridines; Rats; Structure-Activity Relationship; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Jatropholane-type diterpenes from Euphorbia sikkimensis.
Topics: Algorithms; Angiogenesis Inhibitors; Animals; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Euphorbia; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Zebrafish | 2013 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain.
Topics: Alternative Splicing; Animals; Antibodies; Disease Models, Animal; Functional Laterality; Hyperalgesia; Male; Myelin Sheath; Nerve Fibers, Myelinated; Neuralgia; Pain Measurement; Phthalazines; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Sensory Receptor Cells; Serine-Arginine Splicing Factors; Spinal Cord; Time Factors; Vascular Endothelial Growth Factor A; Vesicular Glutamate Transport Protein 1 | 2016 |
Effect of PTK/ZK on the angiogenic switch in head and neck tumors.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Head and Neck Neoplasms; Humans; Interleukin-8; Mice; Mice, SCID; Microvessels; Neoplasm Transplantation; Neovascularization, Pathologic; Phthalazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyridines; Receptors, Vascular Endothelial Growth Factor; Transplantation, Heterologous; Tumor Cells, Cultured | 2008 |
PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling.
Topics: Actins; Animals; Biomarkers; Cell Proliferation; Collagen Type I; Cytoskeleton; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred BALB C; Oncogene Protein v-akt; Phthalazines; Protein Kinase Inhibitors; Pyridines; Rats; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A | 2009 |
Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Physiologic; Oxygen; Phthalazines; Protein Kinase Inhibitors; Pyridines; Receptors, Vascular Endothelial Growth Factor; Retinal Neovascularization; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2009 |
Nanoparticle-mediated endothelial cell-selective delivery of pitavastatin induces functional collateral arteries (therapeutic arteriogenesis) in a rabbit model of chronic hind limb ischemia.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Cells, Cultured; Chronic Disease; Collateral Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Electric Stimulation; Endothelial Cells; Feasibility Studies; Hindlimb Suspension; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intramuscular; Ischemia; Male; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Nanoparticles; Neovascularization, Physiologic; Oxygen; Phthalazines; Protein Kinase Inhibitors; Pyridines; Quinolines; Rabbits; Regional Blood Flow; Time Factors; Vascular Endothelial Growth Factor Receptor-1 | 2010 |
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Glioma; Humans; Lactic Acid; Male; Neovascularization, Pathologic; Phthalazines; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyridines; Rats; Rats, Sprague-Dawley; Temozolomide; Treatment Outcome | 2010 |
In-vivo visualization of tumor microvessel density and response to anti-angiogenic treatment by high resolution MRI in mice.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Mice; Microvessels; Neoplasms; Neovascularization, Pathologic; Phthalazines; Pyridines; Xenograft Model Antitumor Assays | 2011 |
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Topics: Animals; Blister; Body Fluids; Cell Hypoxia; Disease Models, Animal; Ear, Middle; Gene Expression Regulation; Hearing Loss; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Nitroimidazoles; Otitis Media with Effusion; Phthalazines; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A | 2011 |
Vatalanib decrease the positive interaction of VEGF receptor-2 and P2X2/3 receptor in chronic constriction injury rats.
Topics: Animals; Chronic Pain; Disease Models, Animal; Male; Neuralgia; Phthalazines; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Disease Models, Animal; DNA Primers; DNA-Binding Proteins; E2F Transcription Factors; Immunohistochemistry; In Situ Nick-End Labeling; Luciferases; Luminescent Measurements; Mice; Mice, Transgenic; Oligodendroglioma; Phthalazines; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Kinases; Pyridines; Receptor, Platelet-Derived Growth Factor alpha; TOR Serine-Threonine Kinases; Transcription Factors | 2004 |
Intravitreal injection of specific receptor tyrosine kinase inhibitor PTK787/ZK222 584 improves ischemia-induced retinopathy in mice.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Injections; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Phthalazines; Protein Kinase Inhibitors; Pyridines; Reperfusion Injury; Retinal Neovascularization; Treatment Outcome; Vitreous Body | 2005 |
Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment.
Topics: Animals; Carcinoma; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Glucose Transporter Type 1; Humans; Immunohistochemistry; Mammary Neoplasms, Animal; Mice; Misonidazole; Neoplasm Transplantation; Neovascularization, Pathologic; Phthalazines; Positron-Emission Tomography; Pyridines; Transplantation, Homologous | 2006 |
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma.
Topics: Animals; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Drug Combinations; Enzyme Inhibitors; Female; Humans; Isoproterenol; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Organ Size; Ovarian Neoplasms; Phthalazines; Pyridines; Radiography; Random Allocation; Stress, Psychological; Terbutaline; Transplantation, Heterologous; Tumor Burden; Vascular Endothelial Growth Factor A | 2006 |
Inflammatory corneal (lymph)angiogenesis is blocked by VEGFR-tyrosine kinase inhibitor ZK 261991, resulting in improved graft survival after corneal transplantation.
Topics: Animals; Cell Proliferation; Corneal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Graft Survival; Keratoplasty, Penetrating; Lymphangiogenesis; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphorylation; Phthalazines; Protein Kinase Inhibitors; Pyridines; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor Receptor-3 | 2008 |
Vascular endothelial growth factor in chronic rat allograft nephropathy.
Topics: Animals; Cyclosporine; Disease Models, Animal; Graft Rejection; Kidney; Kidney Diseases; Kidney Transplantation; Male; Phthalazines; Protein Kinase Inhibitors; Pyridines; Rats; Signal Transduction; Transplantation, Homologous; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.
Topics: Angiogenesis Inhibitors; Animals; Bone Marrow Cells; Carcinoma; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Hematopoiesis; Humans; Kidney Neoplasms; Leukocytes; Lymphokines; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Phosphorylation; Phthalazines; Platelet-Derived Growth Factor; Pyridines; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wound Healing | 2000 |
Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model.
Topics: Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Carcinoma, Renal Cell; Cell Division; Cyclohexanes; Disease Models, Animal; Enzyme Inhibitors; Female; Kidney Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phthalazines; Pyridines; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Renal Circulation; Sesquiterpenes | 2000 |
Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis.
Topics: Acute Disease; Angiogenesis Inhibitors; Animals; Arteriosclerosis; Chronic Disease; Disease Models, Animal; Disease Progression; Endothelial Growth Factors; Gene Transfer, Horizontal; Graft Rejection; Graft Survival; Heart Transplantation; Immunohistochemistry; In Situ Hybridization; Leukocytes, Mononuclear; Lymphokines; Macrophages; Myocardium; Phthalazines; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Transfection; Transplantation, Heterotopic; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |