vatalanib has been researched along with Astrocytoma, Grade IV in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Achyut, BR; Angara, K; Ara, R; Arbab, AS; Bollag, RJ; Borin, TF; Iskander, A; Lebedyeva, I; Lin, PC; Rashid, MH | 1 |
| Achyut, BR; Angara, K; Ara, R; Arbab, AS; Borin, TF; Iskander, A; Jain, M; Rashid, MH; Shankar, A | 1 |
| Beumer, JH; Desjardins, A; Egorin, MJ; Friedman, HS; Gururangan, S; Herndon, JE; Lagattuta, TF; Reardon, DA; Salvado, AJ; Vredenburgh, JJ | 1 |
| Brandes, AA; Gorlia, T; Hau, P; Kros, JM; Lacombe, D; Mirimanoff, RO; Stupp, R; Tosoni, A; van den Bent, MJ | 1 |
| Batchelor, TT; Doyle, CL; Drappatz, J; Duda, DG; Eichler, AF; Gerstner, ER; Jain, RK; Plotkin, SR; Wen, PY; Xu, L | 1 |
| Brennan, CW; Fomchenko, EI; Fujii, K; Holland, EC; Huse, JT; Ladanyi, M; Levine, RL; Nakada, M; Oka, H; Ozawa, T; Pedraza, A; Sasayama, T; Squatrito, M; Tandon, A; Utsuki, S; Wang, L; Yasui, Y | 1 |
| Choma, M; Cole, P; Kealey, S; Moya, MG; Parks, L; Provenzale, JM; Serajuddin, H; York, G | 1 |
4 trial(s) available for vatalanib and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Hydroxyurea; Imatinib Mesylate; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Middle Aged; Phthalazines; Piperazines; Pyridines; Pyrimidines; Recurrence; Treatment Outcome | 2009 |
EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Phthalazines; Pyridines; Radiotherapy, Adjuvant; Temozolomide; Treatment Outcome | 2010 |
Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Membrane Proteins; Middle Aged; Phthalazines; Polymorphism, Single Nucleotide; Pyridines; Radiotherapy; Receptor, TIE-2; Temozolomide; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Correlation of relative permeability and relative cerebral blood volume in high-grade cerebral neoplasms.
Topics: Adult; Angiogenesis Inhibitors; Blood Volume; Blood-Brain Barrier; Brain; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Contrast Media; Female; Gadolinium DTPA; Glioblastoma; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Phthalazines; Pyridines | 2006 |
3 other study(ies) available for vatalanib and Astrocytoma, Grade IV
| Article | Year |
|---|---|
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy-Resistant Glioblastoma.
Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Interleukin-8; Molecular Targeted Therapy; Neovascularization, Pathologic; Phenylurea Compounds; Phthalazines; Pyridines; Rats, Nude; Receptors, Interleukin-8B; Tissue Array Analysis; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Vascular mimicry in glioblastoma following anti-angiogenic and anti-20-HETE therapies.
Topics: Amidines; Angiogenesis Inhibitors; Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Neovascularization, Pathologic; Phthalazines; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Nude | 2017 |
PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.
Topics: Amino Acid Sequence; Base Sequence; Benzamides; Gene Dosage; Gene Fusion; Gene Rearrangement; Glioblastoma; Humans; Imatinib Mesylate; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Oligodendroglioma; Phosphatidylinositol 3-Kinases; Phosphorylation; Phthalazines; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Transformation, Genetic | 2010 |