vasoactive-intestinal-peptide and Head-and-Neck-Neoplasms

vasoactive-intestinal-peptide has been researched along with Head-and-Neck-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for vasoactive-intestinal-peptide and Head-and-Neck-Neoplasms

ArticleYear
Neurogenic tumors and VIP-induced diarrhea.
    Journal of pediatric surgery, 1979, Volume: 14, Issue:5

    The authors report a case of cervical ganglioneuroblastoma associated with intractable watery diarrhea and hypokalemia. The probable physiopathologic mechanism of the diarrhea and its relation to the vasoactive intestinal peptide secretion (VIP) by the tumor are discussed.

    Topics: Diarrhea, Infantile; Ganglioneuroma; Gastrointestinal Hormones; Head and Neck Neoplasms; Humans; Infant; Male; Vasoactive Intestinal Peptide

1979
Intractable diarrhea in a boy with vasoactive intestinal peptide-producing ganglioneuroblastoma.
    Pediatrics, 1977, Volume: 59, Issue:5

    A 1-year-old boy had intractable diarrhea and symptoms of the watery-diarrhea-hypokalemia-achlorhydria (WDHA) syndrome, a well-known entity in adults. Resection of a ganglioneuroblastoma situated in the neck caused prompt relief of symptoms. The ganglioneuroblastoma in this instance contained the enterohormone vasoactive intestinal peptide (VIP); blood levels of this peptide were elevated preoperatively. After tumor resection, the VIP level returned to normal, and the diarrhea ceased on the day of the operation. The genesis of the diarrhea in relation to the production of polypeptides from neuroendocrine origin is discussed (APUD-cell concept). VIP may be the mediator of the WHDA syndrome in ganglioneuroblastoma.

    Topics: Colon; Diagnosis, Differential; Diarrhea, Infantile; Ganglioneuroma; Gastrointestinal Hormones; Head and Neck Neoplasms; Humans; Infant; Male; Peptides; Vasoactive Intestinal Peptide

1977