vasoactive-intestinal-peptide and Common-Bile-Duct-Neoplasms

vasoactive-intestinal-peptide has been researched along with Common-Bile-Duct-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for vasoactive-intestinal-peptide and Common-Bile-Duct-Neoplasms

Article	Year
Neuroendocrine carcinoma of the ampulla of vater. A case of absence of somatostatin in a vasoactive intestinal polypeptide-, bombesin-, and cholecystokinin-producing tumor. American journal of clinical pathology, 1991, Volume: 95, Issue:1 A 31-year-old patient with a clinical picture of obstructive jaundice had surgical treatment, and a primary carcinoid of the ampulla of Vater (VA) was found. The tumor was studied with light microscopy, immunohistochemistry, and electron microscopy. The neoplasm had histopathologic and cytopathologic features similar to those encountered in typical neuroendocrine neoplasms. It is interesting that immunohistochemical techniques disclosed the presence of vasointestinal polypeptide, cholecystokinin, and bombesin; however, unlike most neuroendocrine neoplasms arising in VA, no somatostatin-immunoreactive cells were found. Topics: Adult; Ampulla of Vater; Bombesin; Cholecystokinin; Common Bile Duct Neoplasms; Endocrine System Diseases; Humans; Male; Microscopy, Electron; Nervous System Neoplasms; Somatostatin; Vasoactive Intestinal Peptide	1991
Human pancreatic polypeptide (HPP) immunoreactivity in an infiltrating endocrine tumour of the papilla of Vater with unusual morphology. Virchows Archiv. A, Pathological anatomy and histology, 1981, Volume: 392, Issue:1 Histological, histochemical and clinical features of an endocrine duodenal tumour situated in the papillary region were studied. The tumour had a remarkable mixed histological growth pattern, consisting of epithelial glandular structures which showed a gradual transition into a spindle-cell tumour, resembling a neurogenic tumour. The neoplasm was considered malignant since it had infiltrated into the muscular layer of the duodenal wall. The tumour was non-argentaffin and non-argyrophil. No serotonin could be demonstrated histochemically. Immunoreactive pancreatic polypeptide (HPP) was detected by indirect immunofluorescence in the majority of tumour cells of the epithelial glandular structures, whereas areas with a spindle-cell pattern were almost unreactive to the HPP-antiserum. No reaction was found with antibodies against gastrin, insulin, glucagon, vasoactive intestinal polypeptide or somatostatin. The patient had no endocrine symptoms that could be ascribed to the production of HPP by the neoplasm. Twenty-four months postoperatively, the patient's serum HPP concentration had begun to rise, suggesting recurrence of the tumour. Topics: Ampulla of Vater; Common Bile Duct Neoplasms; Gastrins; Glucagon; Humans; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Serotonin; Somatostatin; Vasoactive Intestinal Peptide	1981

Article

Year

Neuroendocrine carcinoma of the ampulla of vater. A case of absence of somatostatin in a vasoactive intestinal polypeptide-, bombesin-, and cholecystokinin-producing tumor.

American journal of clinical pathology, 1991, Volume: 95, Issue:1

A 31-year-old patient with a clinical picture of obstructive jaundice had surgical treatment, and a primary carcinoid of the ampulla of Vater (VA) was found. The tumor was studied with light microscopy, immunohistochemistry, and electron microscopy. The neoplasm had histopathologic and cytopathologic features similar to those encountered in typical neuroendocrine neoplasms. It is interesting that immunohistochemical techniques disclosed the presence of vasointestinal polypeptide, cholecystokinin, and bombesin; however, unlike most neuroendocrine neoplasms arising in VA, no somatostatin-immunoreactive cells were found.

Topics: Adult; Ampulla of Vater; Bombesin; Cholecystokinin; Common Bile Duct Neoplasms; Endocrine System Diseases; Humans; Male; Microscopy, Electron; Nervous System Neoplasms; Somatostatin; Vasoactive Intestinal Peptide

1991

Human pancreatic polypeptide (HPP) immunoreactivity in an infiltrating endocrine tumour of the papilla of Vater with unusual morphology.

Virchows Archiv. A, Pathological anatomy and histology, 1981, Volume: 392, Issue:1

Histological, histochemical and clinical features of an endocrine duodenal tumour situated in the papillary region were studied. The tumour had a remarkable mixed histological growth pattern, consisting of epithelial glandular structures which showed a gradual transition into a spindle-cell tumour, resembling a neurogenic tumour. The neoplasm was considered malignant since it had infiltrated into the muscular layer of the duodenal wall. The tumour was non-argentaffin and non-argyrophil. No serotonin could be demonstrated histochemically. Immunoreactive pancreatic polypeptide (HPP) was detected by indirect immunofluorescence in the majority of tumour cells of the epithelial glandular structures, whereas areas with a spindle-cell pattern were almost unreactive to the HPP-antiserum. No reaction was found with antibodies against gastrin, insulin, glucagon, vasoactive intestinal polypeptide or somatostatin. The patient had no endocrine symptoms that could be ascribed to the production of HPP by the neoplasm. Twenty-four months postoperatively, the patient's serum HPP concentration had begun to rise, suggesting recurrence of the tumour.

Topics: Ampulla of Vater; Common Bile Duct Neoplasms; Gastrins; Glucagon; Humans; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Serotonin; Somatostatin; Vasoactive Intestinal Peptide

1981