variecolin and Breast-Neoplasms

variecolin has been researched along with Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for variecolin and Breast-Neoplasms

Article	Year
Secondary metabolites from Aspergillus japonicus CAM231, an endophytic fungus associated with Garcinia preussii. Natural product research, 2017, Volume: 31, Issue:8 Chemical investigation of Aspergillus japonicus CAM231, isolated from the leaf of Garcina preussii collected in Cameroon, yielded two new compounds; one pyrone derivative, hydroxy neovasinin (1) and one phenol derivative, asperolan (2), together with two known compounds neovasifurarone B (3) and variecolin (4). The structures of the two new compounds were established using intensive NMR spectroscopy and HRMS spectra in comparison with data found in literature. The structure of compound 1 was confirmed by single-crystal X-ray crystallographic analysis in combination with NOESY experiment. The new compounds were screened for their cytotoxic and antibacterial properties; however, the tested compounds displayed no significant activities. Topics: Anti-Bacterial Agents; Antineoplastic Agents; Aspergillus; Breast Neoplasms; Cameroon; Cell Line, Tumor; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endophytes; Furans; Garcinia; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Phenols; Pyrones; Secondary Metabolism; Terpenes	2017

Article

Year

Secondary metabolites from Aspergillus japonicus CAM231, an endophytic fungus associated with Garcinia preussii.

Natural product research, 2017, Volume: 31, Issue:8

Chemical investigation of Aspergillus japonicus CAM231, isolated from the leaf of Garcina preussii collected in Cameroon, yielded two new compounds; one pyrone derivative, hydroxy neovasinin (1) and one phenol derivative, asperolan (2), together with two known compounds neovasifurarone B (3) and variecolin (4). The structures of the two new compounds were established using intensive NMR spectroscopy and HRMS spectra in comparison with data found in literature. The structure of compound 1 was confirmed by single-crystal X-ray crystallographic analysis in combination with NOESY experiment. The new compounds were screened for their cytotoxic and antibacterial properties; however, the tested compounds displayed no significant activities.

Topics: Anti-Bacterial Agents; Antineoplastic Agents; Aspergillus; Breast Neoplasms; Cameroon; Cell Line, Tumor; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endophytes; Furans; Garcinia; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Phenols; Pyrones; Secondary Metabolism; Terpenes

2017