varespladib has been researched along with Arthritis, Rheumatoid in 2 studies
*Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arjunan, P; Gopalakrishnakone, P; Kumar, PV; Nagarajarao, LM; Ramapatna, SL; Sato, K; Satyanarayanajois, SD; Thwin, MM | 1 |
| Bradley, JD; Dmitrienko, AA; Gluck, OS; Kivitz, AJ; Myers, SL; Sides, GD; Weaver, AL; Wiesenhutter, C | 1 |
1 trial(s) available for varespladib and Arthritis, Rheumatoid
| Article | Year |
|---|---|
A randomized, double-blinded, placebo-controlled clinical trial of LY333013, a selective inhibitor of group II secretory phospholipase A2, in the treatment of rheumatoid arthritis.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Keto Acids; Middle Aged; Phospholipases A; Phospholipases A2; Placebos | 2005 |
1 other study(ies) available for varespladib and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Novel peptide inhibitors of human secretory phospholipase A2 with antiinflammatory activity: solution structure and molecular modeling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Circular Dichroism; Fibroblasts; Gene Expression; Humans; Magnetic Resonance Spectroscopy; Matrix Metalloproteinases; Models, Molecular; Oligopeptides; Peptides; Peptides, Cyclic; Phospholipases A2, Secretory; Protein Binding; Protein Conformation; Rabbits; Solutions; Structure-Activity Relationship; Synovial Fluid | 2007 |