varenicline has been researched along with Disease Models, Animal in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 22 (68.75) | 24.3611 |
| 2020's | 7 (21.88) | 2.80 |
| Authors | Studies |
|---|---|
| Brieaddy, LE; Burgess, JP; Damaj, MI; Ivy Carroll, F; Lee, JR; Ma, W; Martin, BR; Navarro, HA; Yokota, Y | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chen, M; Chen, Y; Hu, X; Huang, C; Li, A; Lu, W; Qian, C; Wang, J; Zhang, Y; Zhou, Y; Zhu, S | 1 |
| Abreu-Villaça, Y; Araújo, UC; Filgueiras, CC; Isnardo-Fernandes, J; Leal-Rocha, PH; Manhães, AC; Ribeiro-Carvalho, A | 1 |
| Ebrahimi-Kalan, A; Farhoudi, M; Hosseini, L; Kazmi, S; Mahmoudi, J; Rahbarghazi, R; Sadigh-Eteghad, S; Seyedaghamiri, F; Shanehbandi, D | 1 |
| Bernat, P; Kołodziejczyk, P; Tutka, P; Zagaja, M; Łuszczki, JJ | 1 |
| George, O; Smith, LC | 1 |
| Bennet, L; Chen, S; McGregor, AL | 1 |
| Açikalin, Ö; Bölükbaşi Hatip, F; Hatip-Al-Khatib, I; Kataoka, Y; Tan, R; Yamauchi, A | 1 |
| Cann, C; Gould, TJ; Kutlu, MG; Tumolo, JM | 1 |
| Gupta, S; Patel, RK; Sharma, AK; Wardhan, N | 1 |
| Hashidume, N; Kanaoka, Y; Kataoka, Y; Koga, M; Tashiro, T; Yamauchi, A | 1 |
| Bancroft, EA; DuBois, DW; Fincher, AS; Migut, EA; Montgomery, KS; Murchison, D; Provasek, V | 1 |
| Bardo, MT; Bell, RL; Crooks, PA; Dwoskin, LP; Maggio, SE; Nixon, K; Prendergast, MA; Saunders, MA; Zheng, G | 1 |
| Golebiowska, J; Nikiforuk, A; Popik, P; Potasiewicz, A | 1 |
| Adermark, L; Danielsson, K; de Bejczy, A; Ericson, M; Söderpalm, B | 1 |
| Camarasa, J; Ciudad-Roberts, A; Escubedo, E; Pubill, D | 1 |
| Bartholomew, P; Elwell, M; Radi, Z; Vogel, WM | 1 |
| Kanaoka, Y; Kataoka, Y; Koga, M; Kubo, N; Ohishi, K; Ohkido, Y; Sugiyama, K; Yamauchi, A | 1 |
| Becker, C; Bencherif, M; Kucinski, A; Lippiello, P; Stachowiak, EK; Stachowiak, MK; Wersinger, S | 1 |
| Engberg, ME; Johns, BE; Lambert, CS; Philpot, RM; Wecker, L | 1 |
| Coen, K; Funk, D; Lê, AD; Lo, S | 1 |
| Barrett, ST; Bevins, RA; Chou, S; Pittenger, ST | 2 |
| Clemens, KJ; Holmes, NM; Macnamara, CL; Westbrook, RF | 1 |
| Bisha, M; Fahimi, EG; Henning, U; Kojda, G; Lange-Asschenfeldt, C; Schäble, S; Stermann, T; Suvorava, T | 1 |
| Carroll, ME; Smethells, JR; Swalve, N | 1 |
| D'Souza, G; Kim, D; McGregor, AL; Tingle, MD | 1 |
| Gould, TJ; Lerman, C; Portugal, GS; Raybuck, JD | 1 |
| Coe, JW; Guanowsky, V; Mineur, YS; Picciotto, MR; Rollema, H; Seymour, PA; Shrikhande, A | 1 |
| Gardner, PD; Hendrickson, LM; Pang, X; Tapper, AR; Zhao-Shea, R | 1 |
| Campos, C; Huang, LZ; Ivy Carroll, F; Ly, J; Quik, M | 1 |
2 review(s) available for varenicline and Disease Models, Animal
| Article | Year |
|---|---|
Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models.
Topics: Animals; Antidepressive Agents; Bupropion; Disease Models, Animal; Electronic Nicotine Delivery Systems; Humans; Nicotinic Agonists; Receptors, Nicotinic; Smoking Cessation; Smoking Cessation Agents; Tobacco Use Cessation Devices; Tobacco Use Disorder; Varenicline | 2020 |
Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma.
Topics: Animals; Benzazepines; Carcinogenicity Tests; Disease Models, Animal; Humans; Hydromorphone; Lipoma; Mutagenicity Tests; Neoplasms; Phentolamine; Piperidines; Pyrimidines; Pyrroles; Quinoxalines; Rats; Risk Assessment; Varenicline | 2013 |
30 other study(ies) available for varenicline and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs.
Topics: Analgesics; Animals; Body Temperature; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Molecular Structure; Nicotinic Antagonists; Pain; Protein Binding; Pyridines; Radioligand Assay; Receptors, Nicotinic; Structure-Activity Relationship | 2008 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Varenicline improved laparotomy-induced cognitive impairment by restoring mitophagy in aged mice.
Topics: Aging; Animals; Apoptosis; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; eIF-2 Kinase; Laparotomy; Male; Maze Learning; Mice, Inbred C57BL; Mitochondria; Mitophagy; Neurons; Neuroprotective Agents; Oxidative Stress; Perioperative Care; Postoperative Cognitive Complications; STAT3 Transcription Factor; tau Proteins; Varenicline | 2022 |
Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Varenicline | 2021 |
Varenicline improves cognitive impairment in a mouse model of mPFC ischemia: The possible roles of inflammation, apoptosis, and synaptic factors.
Topics: Animals; Anxiety; Apoptosis; Behavior, Animal; Brain Ischemia; Cognitive Dysfunction; Disease Models, Animal; Mice; Neuroinflammatory Diseases; Nicotinic Agonists; Prefrontal Cortex; Synapses; Varenicline | 2022 |
Interaction of Varenicline with Classic Antiseizure Medications in the Mouse Maximal Electroshock-Induced Seizure Model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Varenicline | 2023 |
Delayed Varenicline Administration Reduces Inflammation and Improves Forelimb Use Following Experimental Stroke.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Axons; Basal Ganglia; Disease Models, Animal; Drug Administration Schedule; Encephalitis; Forelimb; GAP-43 Protein; Green Fluorescent Proteins; Infarction, Middle Cerebral Artery; Male; Mice, Transgenic; Motor Activity; Nerve Regeneration; Nicotinic Agonists; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recovery of Function; Time Factors; Varenicline | 2017 |
Effect of varenicline on behavioral deficits in a rat model of Parkinson's disease induced by unilateral 6-hydroxydopamine lesion of substantia nigra.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Motor Activity; Nicotinic Agonists; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substantia Nigra; Varenicline | 2018 |
Differential effects of α4β2 nicotinic receptor antagonists and partial-agonists on contextual fear extinction in male C57BL/6 mice.
Topics: Animals; Anxiety; Azetidines; Dihydro-beta-Erythroidine; Disease Models, Animal; Extinction, Psychological; Fear; Male; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic; Stress Disorders, Post-Traumatic; Varenicline | 2018 |
Haloperidol-induced parkinsonism is attenuated by varenicline in mice.
Topics: Animals; Catalepsy; Disease Models, Animal; Dopamine; Female; Haloperidol; Levodopa; Male; Mice; Neurons; Parkinsonian Disorders; Varenicline | 2018 |
Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase.
Topics: Aconitine; Administration, Inhalation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Emphysema; Mice, Inbred C57BL; Nicotinic Agonists; Pancreatic Elastase; Pulmonary Alveoli; Smoking Cessation; Varenicline | 2018 |
Effects of ethanol and varenicline on female Sprague-Dawley rats in a third trimester model of fetal alcohol syndrome.
Topics: Animals; Anxiety; Basal Forebrain; Disease Models, Animal; Ethanol; Excitatory Postsynaptic Potentials; Female; Fetal Alcohol Spectrum Disorders; Male; Maze Learning; Motor Activity; Pregnancy; Pregnancy Trimester, Third; Rats; Varenicline | 2018 |
An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic α6β2* antagonist r-bPiDI.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Disease Models, Animal; Ethanol; Female; Naltrexone; Nicotine; Nicotinic Antagonists; Picolines; Pyridinium Compounds; Rats; Self Administration; Smoking Cessation Agents; Tobacco Use Disorder; Treatment Outcome; Varenicline | 2018 |
Procognitive effects of varenicline in the animal model of schizophrenia depend on α4β2- and α 7-nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cognition; Cognitive Dysfunction; Disease Models, Animal; Drug Monitoring; Nicotinic Agonists; Rats; Receptors, Nicotinic; Schizophrenia; Treatment Outcome; Varenicline | 2018 |
Combined administration of varenicline and bupropion produces additive effects on accumbal dopamine and abolishes the alcohol deprivation effect in rats.
Topics: Alcohol-Related Disorders; Animals; Bupropion; Disease Models, Animal; Dopamine; Drug Therapy, Combination; Male; Nucleus Accumbens; Rats; Rats, Wistar; Smoking Cessation Agents; Varenicline | 2020 |
Heteromeric nicotinic receptors are involved in the sensitization and addictive properties of MDMA in mice.
Topics: Analysis of Variance; Animals; Benzazepines; Brain; Cholinergic Agents; Conditioning, Operant; Dihydro-beta-Erythroidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hallucinogens; Hyperkinesis; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Protein Binding; Quinoxalines; Radionuclide Imaging; Receptors, Nicotinic; Substance-Related Disorders; Tritium; Varenicline | 2013 |
Varenicline aggravates plaque formation through α7 nicotinic acetylcholine receptors in ApoE KO mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apolipoproteins E; Benzazepines; Body Weight; Cardiovascular Diseases; Cholesterol; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Agonists; Plaque, Atherosclerotic; Quinoxalines; Varenicline | 2014 |
The effects of varenicline on sensory gating and exploratory behavior with pretreatment with nicotinic or 5-HT3A receptor antagonists.
Topics: Animals; Benzazepines; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Nicotinic Agonists; Quinoxalines; Receptors, Serotonin, 5-HT3; Reflex, Startle; Schizophrenia; Sensory Gating; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Varenicline | 2015 |
Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments.
Topics: Animals; Ataxia; Biomechanical Phenomena; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Gait; Male; Niacinamide; Nicotinic Agonists; Olivary Nucleus; Principal Component Analysis; Pyridines; Random Allocation; Rats, Sprague-Dawley; Varenicline; Walking | 2015 |
Effects of varenicline on operant self-administration of alcohol and/or nicotine in a rat model of co-abuse.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Drug Interactions; Ethanol; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Substance-Related Disorders; Varenicline | 2016 |
The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in female rats.
Topics: Amphetamine-Related Disorders; Animals; Catheters, Indwelling; Central Nervous System Stimulants; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Female; Methamphetamine; Motor Activity; Nicotinic Agonists; Psychotropic Drugs; Random Allocation; Rats, Sprague-Dawley; Self Administration; Treatment Outcome; Varenicline | 2016 |
Varenicline impairs extinction and enhances reinstatement across repeated cycles of nicotine self-administration in rats.
Topics: Animals; Catheters, Indwelling; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Self Administration; Tobacco Use Cessation Devices; Tobacco Use Disorder; Varenicline | 2016 |
Effects of varenicline on alpha4-containing nicotinic acetylcholine receptor expression and cognitive performance in mice.
Topics: Administration, Oral; Animals; Brain; Cell Line; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Male; Memory Disorders; Mice, Inbred C57BL; Nootropic Agents; Receptors, Nicotinic; Recognition, Psychology; RNA, Messenger; Scopolamine; Varenicline | 2016 |
Sex differences in attenuation of nicotine reinstatement after individual and combined treatments of progesterone and varenicline.
Topics: Animals; Disease Models, Animal; Drug Combinations; Drug-Seeking Behavior; Extinction, Psychological; Female; Male; Nicotine; Nicotinic Agonists; Progesterone; Progestins; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Sex Factors; Smoking Cessation; Varenicline | 2016 |
The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in male rats.
Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Locomotion; Male; Methamphetamine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Varenicline | 2017 |
Varenicline improves motor and cognitive deficits and decreases depressive-like behaviour in late-stage YAC128 mice.
Topics: Animals; Anxiety; Cell Proliferation; Cognition Disorders; Corpus Striatum; Depression; Disease Models, Animal; Female; Hippocampus; Huntington Disease; Male; Maze Learning; Memory; Mice, Transgenic; Motor Activity; Movement Disorders; Neural Stem Cells; Neuroprotective Agents; Nicotinic Agonists; Varenicline | 2017 |
Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice.
Topics: Animals; Behavior, Animal; Benzazepines; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Learning Disabilities; Male; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Quinoxalines; Tobacco Use Disorder; Varenicline | 2008 |
Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect.
Topics: Animals; Antidepressive Agents; Benzazepines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nicotinic Agonists; Quinoxalines; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Sertraline; Swimming; Varenicline | 2009 |
Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption.
Topics: Alanine; Alcohol Drinking; Analysis of Variance; Animals; Benzazepines; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drinking Behavior; Drug Combinations; Ethanol; Gene Expression Regulation; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, Nicotinic; Tyrosine 3-Monooxygenase; Varenicline; Ventral Tegmental Area | 2010 |
Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats.
Topics: Animals; Antiparkinson Agents; Azetidines; Benzazepines; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Levodopa; Male; Nicotinic Agonists; Oxidopamine; Parkinson Disease; Quinoxalines; Rats; Rats, Sprague-Dawley; Varenicline | 2011 |