vapiprost and Renal-Artery-Obstruction

vapiprost has been researched along with Renal-Artery-Obstruction* in 1 studies

Trials

1 trial(s) available for vapiprost and Renal-Artery-Obstruction

Article	Year
The haemodynamic effects of GR 32191, a thromboxane A2 receptor antagonist, in patients with renal artery stenosis and hypertension. British journal of clinical pharmacology, 1993, Volume: 36, Issue:3 This study was designed to determine if GR 32191 a thromboxane A2 receptor antagonist, would lower blood pressure in patients with hypertension and renal artery stenosis. Eight patients with unilateral atheromatous renal artery stenosis and hypertension were studied in a double-blind, single dose, placebo controlled, crossover study. The results show that, GR 32191, given orally, in doses of 20 mg and 40 mg, does not reduce the blood pressure to any clinically important degree. Topics: Aged; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemodynamics; Heptanoic Acids; Humans; Hypertension, Renovascular; Male; Middle Aged; Receptors, Thromboxane; Renal Artery Obstruction	1993

Article

Year

The haemodynamic effects of GR 32191, a thromboxane A2 receptor antagonist, in patients with renal artery stenosis and hypertension.

British journal of clinical pharmacology, 1993, Volume: 36, Issue:3

This study was designed to determine if GR 32191 a thromboxane A2 receptor antagonist, would lower blood pressure in patients with hypertension and renal artery stenosis. Eight patients with unilateral atheromatous renal artery stenosis and hypertension were studied in a double-blind, single dose, placebo controlled, crossover study. The results show that, GR 32191, given orally, in doses of 20 mg and 40 mg, does not reduce the blood pressure to any clinically important degree.

Topics: Aged; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemodynamics; Heptanoic Acids; Humans; Hypertension, Renovascular; Male; Middle Aged; Receptors, Thromboxane; Renal Artery Obstruction

1993