Page last updated: 2024-10-27

vanoxerine and Tuberculosis, Drug-Resistant

vanoxerine has been researched along with Tuberculosis, Drug-Resistant in 1 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kanvatirth, P1
Jeeves, RE1
Bacon, J1
Besra, GS1
Alderwick, LJ1

Other Studies

1 other study available for vanoxerine and Tuberculosis, Drug-Resistant

ArticleYear
Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Agar; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Drug Design; Drug Reposit

2019