vanoxerine has been researched along with Tuberculosis, Drug-Resistant in 1 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kanvatirth, P | 1 |
Jeeves, RE | 1 |
Bacon, J | 1 |
Besra, GS | 1 |
Alderwick, LJ | 1 |
1 other study available for vanoxerine and Tuberculosis, Drug-Resistant
Article | Year |
---|---|
Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria.
Topics: Agar; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Drug Design; Drug Reposit | 2019 |