vanoxerine has been researched along with Tremor in 2 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Harmaline-induced tremor in rodents is a model of essential tremor." | 7.75 | Pharmacological characterization of harmaline-induced tremor activity in mice. ( Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE, 2009) |
| "Harmaline-induced tremor in rodents is a model of essential tremor." | 3.75 | Pharmacological characterization of harmaline-induced tremor activity in mice. ( Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE, 2009) |
| " Tremorine-induced tremor in mice was inhibited by I-893." | 3.68 | [Pharmacological effects of the novel dopamine uptake inhibitor 1-[2-[bis(4-fluorophenyl)-methoxy]ethyl]-4-(3-phenylpropyl) piperazine dihydrochloride (I-893) on the central nervous system]. ( Hotta, K; Mizusawa, H; Morita, S; Nagase, T; Omote, M; Sakai, K; Yamane, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paterson, NE | 1 |
| Malekiani, SA | 1 |
| Foreman, MM | 1 |
| Olivier, B | 1 |
| Hanania, T | 1 |
| Nagase, T | 1 |
| Hotta, K | 1 |
| Morita, S | 1 |
| Sakai, K | 1 |
| Yamane, M | 1 |
| Omote, M | 1 |
| Mizusawa, H | 1 |
2 other studies available for vanoxerine and Tremor
| Article | Year |
|---|---|
Pharmacological characterization of harmaline-induced tremor activity in mice.
Topics: Affect; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Benzazepines; Carbolines; Chlordiazepo | 2009 |
[Pharmacological effects of the novel dopamine uptake inhibitor 1-[2-[bis(4-fluorophenyl)-methoxy]ethyl]-4-(3-phenylpropyl) piperazine dihydrochloride (I-893) on the central nervous system].
Topics: Animals; Barbiturates; Body Temperature; Catalepsy; Dogs; Dopamine; Dose-Response Relationship, Drug | 1991 |