vanoxerine has been researched along with Pregnancy in 6 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mike, A | 1 |
| Karoly, R | 1 |
| Vizi, ES | 1 |
| Kiss, JP | 1 |
| Choong, KC | 1 |
| Shen, RY | 1 |
| Castagné, V | 1 |
| Cuénod, M | 1 |
| Do, KQ | 1 |
| Hamann, J | 1 |
| Rommelspacher, H | 1 |
| Storch, A | 1 |
| Reichmann, H | 1 |
| Gille, G | 1 |
| Bender, M | 1 |
| Drago, J | 1 |
| Rivkees, SA | 1 |
| Zachor, DA | 1 |
| Moore, JF | 1 |
| Brezausek, C | 1 |
| Theibert, A | 1 |
| Percy, AK | 1 |
6 other studies available for vanoxerine and Pregnancy
| Article | Year |
|---|---|
Inhibitory effect of the DA uptake blocker GBR 12909 on sodium channels of hippocampal neurons.
Topics: Animals; Dopamine Uptake Inhibitors; Electrophysiology; Female; Hippocampus; Membrane Potentials; Ne | 2003 |
Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission.
Topics: Amphetamine; Animals; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Elec | 2004 |
An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain Chemistry; Buthionine Sulfoxi | 2004 |
Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture.
Topics: Adenosine Triphosphate; Animals; Carbolines; Caspase 3; Caspases; Cell Death; Cell Nucleus; Cells, C | 2006 |
D1 receptors mediate dopamine action in the fetal suprachiasmatic nuclei: studies of mice with targeted deletion of the D1 dopamine receptor gene.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Benzazepines; | 1997 |
Cocaine inhibits NGF-induced PC12 cells differentiation through D(1)-type dopamine receptors.
Topics: Animals; Brain; Carrier Proteins; Cell Differentiation; Cocaine; Dopamine; Dopamine D2 Receptor Anta | 2000 |