Page last updated: 2024-10-27

vanoxerine and Necrosis

vanoxerine has been researched along with Necrosis in 1 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamann, J1
Rommelspacher, H1
Storch, A1
Reichmann, H1
Gille, G1

Other Studies

1 other study available for vanoxerine and Necrosis

ArticleYear
Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture.
    Journal of neurochemistry, 2006, Volume: 98, Issue:4

    Topics: Adenosine Triphosphate; Animals; Carbolines; Caspase 3; Caspases; Cell Death; Cell Nucleus; Cells, C

2006