vanoxerine has been researched along with Idiopathic Parkinson Disease in 2 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stopper, H | 1 |
| Schupp, N | 1 |
| Fazeli, G | 1 |
| Dietel, B | 1 |
| Queisser, N | 1 |
| Walitza, S | 1 |
| Gerlach, M | 1 |
| Ding, YS | 1 |
| Fowler, JS | 1 |
| Volkow, ND | 1 |
| Gatley, SJ | 1 |
| Logan, J | 1 |
| Dewey, SL | 1 |
| Alexoff, D | 1 |
| Fazzini, E | 1 |
| Wolf, AP | 1 |
2 other studies available for vanoxerine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Genotoxicity of the neurotransmitter dopamine in vitro.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Dopamine; Humans; Micronucleus Tests; Mutagenicit | 2009 |
Pharmacokinetics and in vivo specificity of [11C]dl-threo-methylphenidate for the presynaptic dopaminergic neuron.
Topics: Aged; Animals; Chromatography, High Pressure Liquid; Dopamine; Dopamine Uptake Inhibitors; Female; H | 1994 |