vanoxerine has been researched along with Hyperactivity, Motor in 4 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, A | 1 |
| de Jong, LA | 1 |
| Kamenski, ME | 1 |
| Higa, KK | 1 |
| Lucero, JD | 1 |
| Young, JW | 1 |
| Behrens, MM | 1 |
| Powell, SB | 1 |
| Douma, TN | 1 |
| Kolarz, A | 1 |
| Postma, Y | 1 |
| Olivier, B | 1 |
| Groenink, L | 1 |
| Carlsson, ML | 1 |
| Martin, P | 1 |
| Nilsson, M | 1 |
| Sorensen, SM | 1 |
| Carlsson, A | 1 |
| Waters, S | 1 |
| Waters, N | 1 |
| Rhodes, JS | 1 |
| Hosack, GR | 1 |
| Girard, I | 1 |
| Kelley, AE | 1 |
| Mitchell, GS | 1 |
| Garland, T | 1 |
1 trial available for vanoxerine and Hyperactivity, Motor
| Article | Year |
|---|---|
Differential sensitivity to acute administration of cocaine, GBR 12909, and fluoxetine in mice selectively bred for hyperactive wheel-running behavior.
Topics: Animals; Animals, Outbred Strains; Breeding; Cocaine; Crosses, Genetic; Dopamine Uptake Inhibitors; | 2001 |
3 other studies available for vanoxerine and Hyperactivity, Motor
| Article | Year |
|---|---|
Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice.
Topics: Animals; Female; GABAergic Neurons; Hyperkinesis; Impulsive Behavior; Interneurons; Male; Mice, Inbr | 2017 |
The amphetamine-chlordiazepoxide mixture, a pharmacological screen for mood stabilizers, does not enhance amphetamine-induced disruption of prepulse inhibition.
Topics: Acoustic Stimulation; Affect; Amphetamine; Analysis of Variance; Animals; Anticonvulsants; Antimanic | 2011 |
The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; | 1999 |