vanoxerine has been researched along with Carcinoma, Hepatocellular in 1 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, Y | 1 |
| Ke, KB | 1 |
| Xia, ZK | 1 |
| Li, HJ | 1 |
| Su, R | 1 |
| Dong, C | 1 |
| Zhou, FM | 1 |
| Wang, L | 1 |
| Chen, R | 1 |
| Wu, SG | 1 |
| Zhao, H | 1 |
| Gu, P | 1 |
| Leung, KS | 1 |
| Wong, MH | 1 |
| Lu, G | 1 |
| Zhang, JY | 1 |
| Jiang, BH | 1 |
| Qiu, JG | 1 |
| Shi, XN | 1 |
| Lin, MC | 1 |
1 other study available for vanoxerine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Discovery of vanoxerine dihydrochloride as a CDK2/4/6 triple-inhibitor for the treatment of human hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Depe | 2021 |