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vanoxerine and Brain Disorders

vanoxerine has been researched along with Brain Disorders in 1 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meloni, R1
Gale, K1

Other Studies

1 other study available for vanoxerine and Brain Disorders

ArticleYear
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
    European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; C

1991