vanoxerine has been researched along with Atrioventricular Nodal Re-Entrant Tachycardia in 1 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vanoxerine is an oral, 1,4-dialkylpiperazine derivative antiarrhythmic drug being evaluated for pharmacological cardioversion of atrial fibrillation (AF)." | 9.22 | Randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of a single oral dose of vanoxerine for the conversion of subjects with recent onset atrial fibrillation or flutter to normal sinus rhythm: RESTORE SR. ( Camm, AJ; Cotter, G; Davison, BA; Dittrich, HC; Feld, G; Iwashita, J; Koch, G; Kowey, PR; Piccini, JP; Pritchett, EL; van Gelder, IC; Waldo, A; Wiener, LE, 2016) |
| "Vanoxerine is an oral, 1,4-dialkylpiperazine derivative antiarrhythmic drug being evaluated for pharmacological cardioversion of atrial fibrillation (AF)." | 5.22 | Randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of a single oral dose of vanoxerine for the conversion of subjects with recent onset atrial fibrillation or flutter to normal sinus rhythm: RESTORE SR. ( Camm, AJ; Cotter, G; Davison, BA; Dittrich, HC; Feld, G; Iwashita, J; Koch, G; Kowey, PR; Piccini, JP; Pritchett, EL; van Gelder, IC; Waldo, A; Wiener, LE, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piccini, JP | 1 |
| Pritchett, EL | 1 |
| Davison, BA | 1 |
| Cotter, G | 1 |
| Wiener, LE | 1 |
| Koch, G | 1 |
| Feld, G | 1 |
| Waldo, A | 1 |
| van Gelder, IC | 1 |
| Camm, AJ | 1 |
| Kowey, PR | 1 |
| Iwashita, J | 1 |
| Dittrich, HC | 1 |
1 trial available for vanoxerine and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of a single oral dose of vanoxerine for the conversion of subjects with recent onset atrial fibrillation or flutter to normal sinus rhythm: RESTORE SR.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Double-Blin | 2016 |