vanoxerine has been researched along with Arrhythmias, Cardiac in 1 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldsmith, P | 1 |
| Golder, Z | 1 |
| Hunt, J | 1 |
| Berghmans, S | 1 |
| Jones, D | 1 |
| Stables, JP | 1 |
| Murphree, L | 1 |
| Howden, D | 1 |
| Newton, PE | 1 |
| Richards, FM | 1 |
1 other study available for vanoxerine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
GBR12909 possesses anticonvulsant activity in zebrafish and rodent models of generalized epilepsy but cardiac ion channel effects limit its clinical utility.
Topics: Animals; Anticonvulsants; Arrhythmias, Cardiac; Dogs; Dopamine Uptake Inhibitors; Electrocardiograph | 2007 |