Page last updated: 2024-10-27

vanoxerine and Alcoholism

vanoxerine has been researched along with Alcoholism in 1 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yoshimoto, K1
Ueda, S1
Nishi, M1
Yang, Y1
Matsushita, H1
Takeuchi, Y1
Kato, B1
Kawai, Y1
Noritake, K1
Kaneda, S1
Sorimachi, Y1
Yasuhara, M1

Other Studies

1 other study available for vanoxerine and Alcoholism

ArticleYear
Changes in dopamine transporter and c-Fos expression in the nucleus accumbens of alcohol-tolerant rats.
    Alcoholism, clinical and experimental research, 2000, Volume: 24, Issue:3

    Topics: Alcoholism; Animals; Carrier Proteins; Central Nervous System Depressants; Cocaine; Dopamine; Dopami

2000