Page last updated: 2024-10-27

vanoxerine and Alcohol Abuse

vanoxerine has been researched along with Alcohol Abuse in 1 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yoshimoto, K1
Ueda, S1
Nishi, M1
Yang, Y1
Matsushita, H1
Takeuchi, Y1
Kato, B1
Kawai, Y1
Noritake, K1
Kaneda, S1
Sorimachi, Y1
Yasuhara, M1

Other Studies

1 other study available for vanoxerine and Alcohol Abuse

ArticleYear
Changes in dopamine transporter and c-Fos expression in the nucleus accumbens of alcohol-tolerant rats.
    Alcoholism, clinical and experimental research, 2000, Volume: 24, Issue:3

    Topics: Alcoholism; Animals; Carrier Proteins; Central Nervous System Depressants; Cocaine; Dopamine; Dopami

2000