vanoxerine has been researched along with Alcohol Abuse in 1 studies
vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Yoshimoto, K | 1 |
Ueda, S | 1 |
Nishi, M | 1 |
Yang, Y | 1 |
Matsushita, H | 1 |
Takeuchi, Y | 1 |
Kato, B | 1 |
Kawai, Y | 1 |
Noritake, K | 1 |
Kaneda, S | 1 |
Sorimachi, Y | 1 |
Yasuhara, M | 1 |
1 other study available for vanoxerine and Alcohol Abuse
Article | Year |
---|---|
Changes in dopamine transporter and c-Fos expression in the nucleus accumbens of alcohol-tolerant rats.
Topics: Alcoholism; Animals; Carrier Proteins; Central Nervous System Depressants; Cocaine; Dopamine; Dopami | 2000 |