Page last updated: 2024-10-27

vanoxerine and Acute Disease

vanoxerine has been researched along with Acute Disease in 2 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
" Initially, dose-response experiments were performed with intrahippocampal perfusions of GBR-12909 and citalopram, respectively, selective dopamine and serotonin re-uptake blockers."5.32Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures. ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2004)
" Initially, dose-response experiments were performed with intrahippocampal perfusions of GBR-12909 and citalopram, respectively, selective dopamine and serotonin re-uptake blockers."1.32Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures. ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clinckers, R1
Smolders, I1
Meurs, A1
Ebinger, G1
Michotte, Y1
Mechan, AO1
Esteban, B1
O'Shea, E1
Elliott, JM1
Colado, MI1
Green, AR1

Other Studies

2 other studies available for vanoxerine and Acute Disease

ArticleYear
Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures.
    Neuropharmacology, 2004, Volume: 47, Issue:7

    Topics: Acute Disease; Animals; Anticonvulsants; Biogenic Monoamines; Citalopram; Dopamine; Dopamine Antagon

2004
The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Animals; Benzazepines; Body Temperature; Corpus Striat

2002