vanilmandelic acid has been researched along with Neurofibromatosis 1 in 3 studies
Vanilmandelic Acid: A 3-O-methyl ether of 3,4-dihydroxymandelic acid. It is an end-stage metabolite of CATECHOLAMINES; EPINEPHRINE; and NOREPINEPHRINE.
vanillylmandelic acid : An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.
Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Where pheochromocytoma is the cause of hypertension, its resection generally results in a better control of hypertension than that obtained in patients whose BPs were elevated from other unknown causes." | 1.26 | The spectrum of pheochromocytoma in hypertensive patients with neurofibromatosis. ( Beierwaltes, WH; Holland, K; Kalff, V; Lloyd, R; Nakajo, M; Shapiro, B; Sisson, JC, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zinnamosca, L | 1 |
| Petramala, L | 1 |
| Cotesta, D | 1 |
| Marinelli, C | 1 |
| Schina, M | 1 |
| Cianci, R | 1 |
| Giustini, S | 1 |
| Sciomer, S | 1 |
| Anastasi, E | 1 |
| Calvieri, S | 1 |
| De Toma, G | 1 |
| Letizia, C | 1 |
| Kalff, V | 1 |
| Shapiro, B | 1 |
| Lloyd, R | 1 |
| Sisson, JC | 1 |
| Holland, K | 1 |
| Nakajo, M | 1 |
| Beierwaltes, WH | 1 |
| Silver, J | 1 |
| Thomas, D | 1 |
| Young, R | 1 |
| Dowling, RH | 1 |
3 other studies available for vanilmandelic acid and Neurofibromatosis 1
| Article | Year |
|---|---|
Neurofibromatosis type 1 (NF1) and pheochromocytoma: prevalence, clinical and cardiovascular aspects.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Adult; Blood Pressure; Blood Pressure Monitoring, Ambulato | 2011 |
The spectrum of pheochromocytoma in hypertensive patients with neurofibromatosis.
Topics: 3-Iodobenzylguanidine; Adolescent; Adrenal Gland Neoplasms; Adult; Epinephrine; Female; Guanidines; | 1982 |
Phaeochromocytoma of the bladder.
Topics: Aged; Catecholamines; Epinephrine; Female; Humans; Hypertension; Microscopy, Electron; Neurofibromat | 1971 |