vanilmandelic acid has been researched along with Menkes Kinky Hair Syndrome in 6 studies
Vanilmandelic Acid: A 3-O-methyl ether of 3,4-dihydroxymandelic acid. It is an end-stage metabolite of CATECHOLAMINES; EPINEPHRINE; and NOREPINEPHRINE.
vanillylmandelic acid : An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.
Menkes Kinky Hair Syndrome: An inherited disorder of copper metabolism transmitted as an X-linked trait and characterized by the infantile onset of HYPOTHERMIA, feeding difficulties, hypotonia, SEIZURES, bony deformities, pili torti (twisted hair), and severely impaired intellectual development. Defective copper transport across plasma and endoplasmic reticulum membranes results in copper being unavailable for the synthesis of several copper containing enzymes, including PROTEIN-LYSINE 6-OXIDASE; CERULOPLASMIN; and SUPEROXIDE DISMUTASE. Pathologic changes include defects in arterial elastin, neuronal loss, and gliosis. (From Menkes, Textbook of Child Neurology, 5th ed, p125)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disulfiram was orally given, in addition to a parenteral administration of copper-histidine in the case of MD patients." | 2.77 | Effects of disulfiram treatment in patients with Menkes disease and occipital horn syndrome. ( Kodama, H; Ogawa, E, 2012) |
| "Menkes disease is a lethal disorder associated with copper metabolism." | 1.42 | Standard values for the urine HVA/VMA ratio in neonates as a screen for Menkes disease. ( Iijima, K; Koda, T; Kodama, H; Kusunoki, N; Lee, T; Matsuo, K; Miwa, A; Morioka, I; Nagasaka, M; Shibata, A; Takeshima, Y; Yagi, M; Yokota, T, 2015) |
| "Menkes disease is a disorder of copper transport that results in early death." | 1.33 | Screening for Menkes disease using the urine HVA/VMA ratio. ( Hamasaki, Y; Kodama, H; Matsuo, M; Tasaki, R, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, T | 3 |
| Yagi, M | 3 |
| Kusunoki, N | 3 |
| Nagasaka, M | 2 |
| Koda, T | 2 |
| Matsuo, K | 2 |
| Yokota, T | 2 |
| Miwa, A | 2 |
| Shibata, A | 2 |
| Morioka, I | 3 |
| Kodama, H | 5 |
| Takeshima, Y | 3 |
| Iijima, K | 3 |
| Awano, H | 1 |
| Matsuo, M | 2 |
| Tasaki, R | 2 |
| Iwanaga, M | 1 |
| Takayanagi, T | 1 |
| Ogawa, E | 1 |
| Hamasaki, Y | 1 |
1 trial available for vanilmandelic acid and Menkes Kinky Hair Syndrome
| Article | Year |
|---|---|
Effects of disulfiram treatment in patients with Menkes disease and occipital horn syndrome.
Topics: Adolescent; Adult; Ceruloplasmin; Copper; Cutis Laxa; Disulfiram; Dopamine; Ehlers-Danlos Syndrome; | 2012 |
5 other studies available for vanilmandelic acid and Menkes Kinky Hair Syndrome
| Article | Year |
|---|---|
Standard values for the urine HVA/VMA ratio in neonates as a screen for Menkes disease.
Topics: Chromatography, High Pressure Liquid; Early Diagnosis; Female; Homovanillic Acid; Humans; Infant, Ne | 2015 |
[Clinical manifestations of three neonates with family histories of Menkes disease].
Topics: Child, Preschool; Early Diagnosis; Genetic Predisposition to Disease; Genetic Testing; Homovanillic | 2014 |
Reply to the letter: "Neonatal screening for Menkes disease using urine HVA/VMA ratio".
Topics: Homovanillic Acid; Humans; Infant; Infant, Newborn; Menkes Kinky Hair Syndrome; Neonatal Screening; | 2016 |
Neonatal screening for Menkes disease using urine HVA/VMA ratio.
Topics: Homovanillic Acid; Humans; Infant; Infant, Newborn; Menkes Kinky Hair Syndrome; Neonatal Screening; | 2016 |
Screening for Menkes disease using the urine HVA/VMA ratio.
Topics: Alleles; Chromatography, High Pressure Liquid; Copper; Dopamine beta-Hydroxylase; Dose-Response Rela | 2005 |