vanilmandelic acid has been researched along with Depressive Disorder in 35 studies
Vanilmandelic Acid: A 3-O-methyl ether of 3,4-dihydroxymandelic acid. It is an end-stage metabolite of CATECHOLAMINES; EPINEPHRINE; and NOREPINEPHRINE.
vanillylmandelic acid : An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To elucidate the influence of total sleep deprivation (TSD) on catecholaminergic neurotransmission, which is assumed to be disturbed in depression, 9 depressive patients collected consecutive 24-h urine samples prior to (baseline), during (TSD) and following total sleep deprivation (post-TSD)." | 1.29 | The influence of total sleep deprivation on urinary excretion of catecholamine metabolites in major depression. ( Berger, M; Müller, HU; Müller, WE; Riemann, D, 1993) |
| "Recurrent fall/winter depressions that remit during spring and summer have been called Seasonal Affective Disorders (SAD) (Wehr and Rosenthal 1989)." | 1.28 | Changes in norepinephrine output following light therapy for fall/winter seasonal depression. ( Anderson, JL; Bloomingdale, KL; Mooney, JJ; Samson, JA; Schildkraut, JJ; Vasile, RG, 1992) |
| "Treatment with lithium carbonate significantly reduced urinary norepinephrine, normetanephrine, 3-methoxy-4-hydroxyphenylglycol, and vanillylmandelic acid output as well as whole-body norepinephrine turnover." | 1.27 | Electroconvulsive treatment and lithium carbonate. Their effects on norepinephrine metabolism in patients with primary, major depressions. ( Karoum, F; Linnoila, M; Potter, WZ; Rosenthal, N, 1983) |
| "Thirteen patients with endogenous depression, compared to 25 normal controls, had a significantly greater ratio of the urinary excretion of norepinephrine plus its metabolite normetanephrine to either the sum of the two urinary norepinephrine metabolites 3-methoxy-4-hydroxyphenylglycol plus vanillylmandelic acid or to the sum of urinary norepinephrine and all of its metabolites." | 1.27 | Relative activity of metabolic pathways for norepinephrine in endogenous depression. ( Karoum, F; Linnoila, M; Pickar, D; Roy, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (74.29) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 2 (5.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jähnel, M | 1 |
| Tajiri, S | 1 |
| Linnoila, M | 14 |
| Karoum, F | 12 |
| Miller, T | 1 |
| Potter, WZ | 7 |
| Kelwala, S | 1 |
| Jones, D | 1 |
| Sitaram, N | 1 |
| Calil, HM | 1 |
| Kopin, IJ | 4 |
| Rosenthal, N | 1 |
| Jimerson, DC | 2 |
| Markey, SP | 2 |
| Ebert, MH | 2 |
| Polinsky, RJ | 1 |
| Schatzberg, AF | 3 |
| Orsulak, PJ | 3 |
| Rosenbaum, AH | 2 |
| Maruta, T | 1 |
| Kruger, ER | 2 |
| Cole, JO | 3 |
| Schildkraut, JJ | 5 |
| Blombery, PA | 1 |
| Gordon, EK | 1 |
| Müller, HU | 1 |
| Riemann, D | 1 |
| Berger, M | 1 |
| Müller, WE | 1 |
| Grossman, F | 1 |
| Anderson, JL | 1 |
| Vasile, RG | 1 |
| Mooney, JJ | 1 |
| Bloomingdale, KL | 2 |
| Samson, JA | 2 |
| Moleman, P | 1 |
| Tulen, JH | 1 |
| Blankestijn, PJ | 1 |
| Man in 't Veld, AJ | 1 |
| Boomsma, F | 1 |
| Maes, M | 2 |
| Vandewoude, M | 2 |
| Schotte, C | 2 |
| Martin, M | 2 |
| Blockx, P | 2 |
| D'Hondt, P | 1 |
| Scharpe, S | 1 |
| Baker, NJ | 1 |
| Staunton, M | 1 |
| Adler, LE | 1 |
| Gerhardt, GA | 1 |
| Drebing, C | 1 |
| Waldo, M | 1 |
| Nagamoto, H | 1 |
| Freedman, R | 1 |
| Secunda, SK | 1 |
| Cross, CK | 1 |
| Koslow, S | 1 |
| Katz, MM | 1 |
| Kocsis, JH | 1 |
| Maas, JW | 2 |
| Corona, GL | 1 |
| Cucchi, ML | 1 |
| Frattini, P | 1 |
| Santagostino, G | 1 |
| Schinelli, S | 1 |
| Comincioli, V | 1 |
| Zerbi, F | 1 |
| Fenoglio, L | 1 |
| Savoldi, F | 1 |
| Gerson, B | 1 |
| Kizuka, PP | 1 |
| Roy, A | 8 |
| Pickar, D | 8 |
| De Jong, J | 2 |
| Anokhina, ID | 1 |
| Bol'shakova, TD | 1 |
| Bremer, GP | 1 |
| Buniatian, AF | 1 |
| Ignatenko, LL | 1 |
| Guthrie, S | 1 |
| Oliver, J | 1 |
| Adinoff, B | 1 |
| Chrousos, GP | 1 |
| Gold, PW | 1 |
| Koslow, SH | 1 |
| Davis, J | 1 |
| Katz, M | 1 |
| Frazer, A | 1 |
| Bowden, CL | 1 |
| Berman, N | 1 |
| Gibbons, R | 1 |
| Stokes, P | 1 |
| Landis, DH | 1 |
| Douillet, P | 1 |
| Siever, LJ | 1 |
| Uhde, TW | 1 |
| Lake, CR | 1 |
| Murphy, DL | 1 |
2 reviews available for vanilmandelic acid and Depressive Disorder
| Article | Year |
|---|---|
[Vanillylmandelic acid (VMA) and homovanillic acid (HVA)].
Topics: Adrenal Gland Neoplasms; Biomarkers; Chromatography, High Pressure Liquid; Chronic Disease; Depressi | 2005 |
Disposition and metabolism of MHPG in humans: application to studies in depression.
Topics: Adrenal Gland Diseases; Adrenal Medulla; Autonomic Nervous System Diseases; Biotransformation; Body | 1984 |
2 trials available for vanilmandelic acid and Depressive Disorder
| Article | Year |
|---|---|
Alteration of norepinephrine metabolism with desipramine and zimelidine in depressed patients.
Topics: Antidepressive Agents; Brain; Brompheniramine; Depressive Disorder; Desipramine; Female; Humans; Mal | 1982 |
Urinary excretion of catecholamines and their metabolites in relation to circulating catecholamines. Six-hour infusion of epinephrine and norepinephrine in healthy volunteers.
Topics: Adult; Depressive Disorder; Double-Blind Method; Epinephrine; Humans; Infusions, Intravenous; Male; | 1992 |
31 other studies available for vanilmandelic acid and Depressive Disorder
| Article | Year |
|---|---|
[Pseudopheochromocytoma in Parkinson disease and depression].
Topics: Adrenal Gland Neoplasms; Antidepressive Agents; Antiparkinson Agents; Catecholamines; Depressive Dis | 2003 |
Reliability of urinary monoamine and metabolite output measurements in depressed patients.
Topics: Depressive Disorder; Dopamine; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 1983 |
Monoamine metabolites as predictors of antidepressant response: a critique.
Topics: Antidepressive Agents; Brain; Depressive Disorder; Dopamine beta-Hydroxylase; Homovanillic Acid; Hum | 1983 |
Electroconvulsive treatment and lithium carbonate. Their effects on norepinephrine metabolism in patients with primary, major depressions.
Topics: Brompheniramine; Clorgyline; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Hu | 1983 |
Toward a biochemical classification of depressive disorders, V: Heterogeneity of unipolar depressions.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Glycols; Humans; Methoxyhydroxyphenylglycol; Psychotic | 1982 |
High correlation of norepinephrine and its major metabolite excretion rates.
Topics: Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged | 1982 |
High positive correlation between urinary free tyramine excretion rate and "whole body" norepinephrine turnover in depressed patients.
Topics: Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged | 1982 |
The biochemical discrimination of subtypes of depressive disorders: an outline of our studies on norepinephrine metabolism and psychoactive drugs in the endogenous depressions since 1967.
Topics: Animals; Antidepressive Agents; Bipolar Disorder; Brain; Depressive Disorder; Disease Models, Animal | 1982 |
Conversion of MHPG to vanillylmandelic acid. Implications for the importance of urinary MHPG.
Topics: Adolescent; Adult; Bipolar Disorder; Brain; Depressive Disorder; Female; Glycols; Humans; Male; Meth | 1980 |
Catecholamine measures for diagnosis and treatment of patients with depressive disorders.
Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Catecholamines; Depressive Disorder; Epinephrine | 1980 |
The influence of total sleep deprivation on urinary excretion of catecholamine metabolites in major depression.
Topics: Adult; Aged; Catecholamines; Chromatography, Liquid; Depressive Disorder; Female; Homovanillic Acid; | 1993 |
Catecholamines in depression: a cumulative study of urinary norepinephrine and its major metabolites in unipolar and bipolar depressed patients versus healthy volunteers at the NIMH.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder; Female; Humans; Longitudinal Stu | 1999 |
Changes in norepinephrine output following light therapy for fall/winter seasonal depression.
Topics: Adult; Arousal; Bipolar Disorder; Depressive Disorder; Female; Humans; Methoxyhydroxyphenylglycol; M | 1992 |
Positive relationship between the catecholaminergic turnover and the DST results in depression.
Topics: Adrenocorticotropic Hormone; Adult; Catecholamines; Depressive Disorder; Dexamethasone; Epinephrine; | 1990 |
The decreased availability of L-tryptophan in depressed females: clinical and biological correlates.
Topics: Adrenocorticotropic Hormone; Adult; Amino Acids; Analysis of Variance; Depression; Depressive Disord | 1990 |
Sensory gating deficits in psychiatric inpatients: relation to catecholamine metabolites in different diagnostic groups.
Topics: Adult; Arousal; Attention; Bipolar Disorder; Brain; Catecholamines; Depressive Disorder; Evoked Pote | 1990 |
Studies of amine metabolites in depressed patients. Relationship to suicidal behavior.
Topics: Bipolar Disorder; Brain; Depressive Disorder; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone | 1986 |
Noradrenergic output and clinical response in depressed women during amitriptyline therapy.
Topics: Adult; Amitriptyline; Depressive Disorder; Female; Humans; Methoxyhydroxyphenylglycol; Middle Aged; | 1989 |
Toward a biochemical classification of depressive disorders. X. Urinary catecholamines, their metabolites, and D-type scores in subgroups of depressive disorders.
Topics: Adolescent; Adult; Age Factors; Aged; Algorithms; Bipolar Disorder; Depressive Disorder; Diagnosis, | 1989 |
Suicidal behavior in depression: relationship to noradrenergic function.
Topics: Adult; Bipolar Disorder; Blood-Brain Barrier; Brain; Depressive Disorder; Female; Humans; Male; Meth | 1989 |
[Features of the functioning of the catecholamine and adrenocortical systems of patients with depression and different degrees of emotional tension].
Topics: 11-Hydroxycorticosteroids; Adrenal Cortex; Catecholamines; Depressive Disorder; Dexamethasone; Dihyd | 1986 |
High intercorrelations among urinary outputs of norepinephrine and its major metabolites. A replication in depressed patients and controls.
Topics: Adult; Depressive Disorder; Female; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; | 1988 |
Urinary-free cortisol in depressed patients and controls: relationship to urinary indices of noradrenergic function.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Li | 1988 |
High correlations of norepinephrine, dopamine, and epinephrine and their major metabolite excretion rates.
Topics: Adult; Alcoholism; Circadian Rhythm; Depressive Disorder; Dopamine; Epinephrine; Female; Homovanilli | 1988 |
Norepinephrine and its metabolites in cerebrospinal fluid, plasma, and urine. Relationship to hypothalamic-pituitary-adrenal axis function in depression.
Topics: Adult; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal S | 1988 |
Cerebrospinal fluid corticotropin-releasing hormone in depression: relationship to noradrenergic function.
Topics: Adult; Corticotropin-Releasing Hormone; Depressive Disorder; Dexamethasone; Female; Humans; Male; Me | 1987 |
Catecholamine metabolism and disposition in healthy and depressed subjects.
Topics: Adult; Aged; Bipolar Disorder; Brain; Catecholamines; Depressive Disorder; Diagnosis, Differential; | 1987 |
Relative activity of metabolic pathways for norepinephrine in endogenous depression.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Nor | 1986 |
Urinary monoamines and monoamine metabolites in subtypes of unipolar depressive disorder and normal controls.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Catecholamines; Depressive Disorder; Dopamine; Female; | 1986 |
Indices of noradrenergic output in depression.
Topics: Adult; Blood Pressure; Depressive Disorder; Female; Heart Rate; Humans; Male; Metanephrine; Methoxyh | 1986 |
Urinary excretion of free tyramine and of norepinephrine and its metabolites in unipolar depressed patients.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Nor | 1986 |