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vanilmandelic acid and Bipolar Disorder

vanilmandelic acid has been researched along with Bipolar Disorder in 44 studies

Vanilmandelic Acid: A 3-O-methyl ether of 3,4-dihydroxymandelic acid. It is an end-stage metabolite of CATECHOLAMINES; EPINEPHRINE; and NOREPINEPHRINE.
vanillylmandelic acid : An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Recurrent fall/winter depressions that remit during spring and summer have been called Seasonal Affective Disorders (SAD) (Wehr and Rosenthal 1989)."1.28Changes in norepinephrine output following light therapy for fall/winter seasonal depression. ( Anderson, JL; Bloomingdale, KL; Mooney, JJ; Samson, JA; Schildkraut, JJ; Vasile, RG, 1992)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199039 (88.64)18.7374
1990's5 (11.36)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schatzberg, AF5
Orsulak, PJ5
Rosenbaum, AH2
Maruta, T1
Kruger, ER2
Cole, JO5
Schildkraut, JJ11
Pflug, B1
Engelmann, W1
Gaertner, HJ1
Linnoila, M2
Karoum, F2
Potter, WZ2
Moody, JP2
Smith, AH1
Naylor, GJ2
Blombery, PA1
Kopin, IJ1
Gordon, EK4
Markey, SP1
Ebert, MH1
Grossman, F1
Praag, HM1
Gudeman, JE2
Rohde, WA2
LaBrie, RA2
Bond, PA1
Dimitrakoudi, M1
Howlett, DR1
Jenner, FA1
Deleon-Jones, F1
Maas, JW7
Dekirmenjian, H3
Sanchez, J1
Jimerson, DC1
Post, RM1
Goodwin, FK1
Anderson, JL1
Vasile, RG1
Mooney, JJ1
Bloomingdale, KL2
Samson, JA2
Swann, AC2
Secunda, SK3
Koslow, SH3
Katz, MM3
Bowden, CL2
Davis, JM2
Robins, E2
Baker, NJ1
Staunton, M1
Adler, LE2
Gerhardt, GA2
Drebing, C2
Waldo, M1
Nagamoto, H2
Freedman, R2
Franks, R1
Baker, N1
Cross, CK1
Koslow, S1
Kocsis, JH1
Javaid, J1
Gerson, B1
Kizuka, PP1
Roy, A1
Pickar, D1
De Jong, J1
Davis, J1
Katz, M1
Frazer, A1
Berman, N1
Gibbons, R1
Stokes, P1
Landis, DH1
Rosenblatt, S3
Chanley, JD3
Leighton, WP3
Fawcett, JA1
McNamee, HB1
Savage, C3
Messiha, FS3
Turek, I1
Hanlon, TE1
Greenspan, K2
Levy, B1
Durell, J2
Draskoczy, PR1
Gershon, ES1
Reich, P1
Grab, EL1
Catalano, A3
Campanini, T2
De Risio, C3
Bojanovsky, J1
Rubin, RT1
Overall, JE1
Mueller, PS1
Bunney, WE1
Weil-Malherbe, H1
Cardon, PV1
Agallianos, D1
Clower, C1
Baer, L1
Aronoff, MS1
Mardighian, G1
Clower, CG1
Messiha, F1
Fawcett, J1
Takahashi, R1
Nagao, Y1
Tsuchiya, K1
Takamizawa, M1
Kobayashi, T1
Toru, M1
Kobayashi, K1
Kariya, T1

Reviews

1 review available for vanilmandelic acid and Bipolar Disorder

ArticleYear
MHPG excretion by patients with affective disorders.
    International pharmacopsychiatry, 1974, Volume: 9, Issue:1

    Topics: Affective Symptoms; Bipolar Disorder; Brain; Catecholamines; Creatinine; Depression; Desipramine; De

1974

Trials

1 trial available for vanilmandelic acid and Bipolar Disorder

ArticleYear
Catecholamine metabolism in affective disorders. II. Norepinephrine, normetanephrine, epinephrine, metanephrine, and VMA excretion in hypomanic patients.
    Archives of general psychiatry, 1969, Volume: 21, Issue:6

    Topics: Adult; Aged; Bipolar Disorder; Catecholamines; Clinical Trials as Topic; Epinephrine; Female; Humans

1969

Other Studies

42 other studies available for vanilmandelic acid and Bipolar Disorder

ArticleYear
Toward a biochemical classification of depressive disorders, V: Heterogeneity of unipolar depressions.
    The American journal of psychiatry, 1982, Volume: 139, Issue:4

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Glycols; Humans; Methoxyhydroxyphenylglycol; Psychotic

1982
Circadian course of body temperature and the excretion of MHPG and VMA in a patient with bipolar depression.
    Journal of neural transmission, 1982, Volume: 53, Issue:2-3

    Topics: Adult; Bipolar Disorder; Body Temperature; Circadian Rhythm; Female; Glycols; Humans; Methoxyhydroxy

1982
High positive correlation between urinary free tyramine excretion rate and "whole body" norepinephrine turnover in depressed patients.
    Biological psychiatry, 1982, Volume: 17, Issue:9

    Topics: Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged

1982
The biochemical discrimination of subtypes of depressive disorders: an outline of our studies on norepinephrine metabolism and psychoactive drugs in the endogenous depressions since 1967.
    Pharmacopsychiatria, 1982, Volume: 15, Issue:4

    Topics: Animals; Antidepressive Agents; Bipolar Disorder; Brain; Depressive Disorder; Disease Models, Animal

1982
The effect of mianserin on urinary catecholamine excretion in psychiatric patients.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:1

    Topics: Bipolar Disorder; Catecholamines; Dibenzazepines; Female; Humans; Metanephrine; Mianserin; Vanilmand

1981
Conversion of MHPG to vanillylmandelic acid. Implications for the importance of urinary MHPG.
    Archives of general psychiatry, 1980, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Bipolar Disorder; Brain; Depressive Disorder; Female; Glycols; Humans; Male; Meth

1980
Catecholamine measures for diagnosis and treatment of patients with depressive disorders.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:12 Pt 2

    Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Catecholamines; Depressive Disorder; Epinephrine

1980
Catecholamines in depression: a cumulative study of urinary norepinephrine and its major metabolites in unipolar and bipolar depressed patients versus healthy volunteers at the NIMH.
    Psychiatry research, 1999, Jul-30, Volume: 87, Issue:1

    Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder; Female; Humans; Longitudinal Stu

1999
The Harold E. Himwich Memorial Lecture. Significance of biochemical parameters in the diagnosis, treatment, and prevention of depressive disorders.
    Biological psychiatry, 1977, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Autopsy; Bipolar Disorder; Brain Chemistry; C

1977
Toward a biochemical classification of depressive disorders. I. Differences in urinary excretion of MHPG and other catecholamine metabolites in clinically defined subtypes of depressions.
    Archives of general psychiatry, 1978, Volume: 35, Issue:12

    Topics: Adult; Bipolar Disorder; Depression; Epinephrine; Female; Glycols; Humans; Male; Metanephrine; Metho

1978
Toward a biochemical classification of depressive disorders. II. Application of multivariate discriminant function analysis to data on urinary catecholamines and metabolites.
    Archives of general psychiatry, 1978, Volume: 35, Issue:12

    Topics: Adult; Bipolar Disorder; Depression; Epinephrine; Factor Analysis, Statistical; Female; Glycols; Hum

1978
Urinary excretion of the sulphate and glucuronide of 3-methoxy-4-hydroxyphenylethyleneglycol in a manic-depressive patient.
    Psychological medicine, 1975, Volume: 5, Issue:3

    Topics: Adult; Bipolar Disorder; Emotions; Female; Glycols; Humans; Lithium; Motor Activity; Sulfates; Vanil

1975
Diagnostic subgroups of affective disorders and their urinary excretion of catecholamine metabolities.
    The American journal of psychiatry, 1975, Volume: 132, Issue:11

    Topics: Bipolar Disorder; Catecholamines; Depression; Female; Humans; Metanephrine; Methoxyhydroxyphenylglyc

1975
Central noradrenergic function in man: vanillylmandelic acid in CSF.
    Brain research, 1975, Dec-05, Volume: 99, Issue:2

    Topics: Acute Disease; Affective Symptoms; Bipolar Disorder; Depression; Homovanillic Acid; Humans; Hydroxyi

1975
Changes in norepinephrine output following light therapy for fall/winter seasonal depression.
    Biological psychiatry, 1992, Oct-15, Volume: 32, Issue:8

    Topics: Adult; Arousal; Bipolar Disorder; Depressive Disorder; Female; Humans; Methoxyhydroxyphenylglycol; M

1992
Mania: sympathoadrenal function and clinical state.
    Psychiatry research, 1991, Volume: 37, Issue:2

    Topics: Adrenal Medulla; Adult; Anxiety; Behavior; Bipolar Disorder; Catecholamines; Epinephrine; Female; Ho

1991
Sensory gating deficits in psychiatric inpatients: relation to catecholamine metabolites in different diagnostic groups.
    Biological psychiatry, 1990, Mar-01, Volume: 27, Issue:5

    Topics: Adult; Arousal; Attention; Bipolar Disorder; Brain; Catecholamines; Depressive Disorder; Evoked Pote

1990
Sensory physiology and catecholamines in schizophrenia and mania.
    Psychiatry research, 1990, Volume: 31, Issue:3

    Topics: Adult; Arousal; Bipolar Disorder; Dopamine; Electroencephalography; Evoked Potentials, Auditory; Fem

1990
Studies of amine metabolites in depressed patients. Relationship to suicidal behavior.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Bipolar Disorder; Brain; Depressive Disorder; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone

1986
Lithium carbonate treatment of mania. Cerebrospinal fluid and urinary monoamine metabolites and treatment outcome.
    Archives of general psychiatry, 1987, Volume: 44, Issue:4

    Topics: Adult; Aged; Bipolar Disorder; Brain; Dopamine; Epinephrine; Female; Homovanillic Acid; Humans; Hydr

1987
Toward a biochemical classification of depressive disorders. X. Urinary catecholamines, their metabolites, and D-type scores in subgroups of depressive disorders.
    Archives of general psychiatry, 1989, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Algorithms; Bipolar Disorder; Depressive Disorder; Diagnosis,

1989
Suicidal behavior in depression: relationship to noradrenergic function.
    Biological psychiatry, 1989, Feb-01, Volume: 25, Issue:3

    Topics: Adult; Bipolar Disorder; Blood-Brain Barrier; Brain; Depressive Disorder; Female; Humans; Male; Meth

1989
Catecholamine metabolism and disposition in healthy and depressed subjects.
    Archives of general psychiatry, 1987, Volume: 44, Issue:4

    Topics: Adult; Aged; Bipolar Disorder; Brain; Catecholamines; Depressive Disorder; Diagnosis, Differential;

1987
The investigation of adrenergic metabolism with 7H3-norepinephrine in psychiatric disorders. II. Temporal changes in the distribution of urinary tritiated metabolites in affective disorders.
    Journal of psychiatric research, 1969, Volume: 6, Issue:4

    Topics: Adjustment Disorders; Adult; Aged; Amines; Bipolar Disorder; Depression; Female; Humans; Injections,

1969
Catecholamine metabolism in affective disorders: excretion of 3-methoxy-4-hydroxymandelic acid in depressive states.
    Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:3

    Topics: Adjustment Disorders; Adult; Aged; Bipolar Disorder; Depression; Humans; Middle Aged; Vanilmandelic

1972
Psychiatric and biochemical profiles of lithium therapy in mania. (Case report).
    Diseases of the nervous system, 1972, Volume: 33, Issue:6

    Topics: Adult; Bipolar Disorder; Dopamine; Female; Homovanillic Acid; Humans; Lithium; Norepinephrine; Norme

1972
Dopamine-beta-hydroxylase: evidence for increased activity in sympathetic neurons during psychotic states.
    Science (New York, N.Y.), 1973, Nov-20, Volume: 182, Issue:4115

    Topics: Bipolar Disorder; Dopamine; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Male; Methoxyhydro

1973
The effects of lithium on norepinephrine turnover and metabolism: basic and clinical studies.
    The Journal of nervous and mental disease, 1974, Volume: 158, Issue:5

    Topics: Animals; Bipolar Disorder; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Humans; Imipram

1974
A psychopharmacological study of catecholamines in affective disorders.
    The Journal of nervous and mental disease, 1974, Volume: 158, Issue:5

    Topics: Adult; Affective Symptoms; Bipolar Disorder; Catecholamines; Dopamine; Electroconvulsive Therapy; Fe

1974
Catecholamine metabolism in affective disorders. IV. Preliminary studies of norepinephrine metabolism in depressed patients treated with amitriptyline.
    Journal of psychiatric research, 1972, Volume: 9, Issue:3

    Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Catechols; Chromatography, Gas; Depression; Female; Gl

1972
[Urinary excretion of vanilmandelic acid in various clinical phases of manic-depressive psychosis].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1971, Apr-30, Volume: 95, Issue:2

    Topics: Adult; Bipolar Disorder; Female; Humans; Mandelic Acids; Middle Aged; Vanilmandelic Acid

1971
[Biochemical correlates of a 48 hour periodic psychosis].
    Psychiatria clinica, 1971, Volume: 4, Issue:5

    Topics: 17-Ketosteroids; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bipolar Dis

1971
Manifest psychopathology and urine biochemical measures. Multivariate analyses in manic-depressive illness.
    Archives of general psychiatry, 1970, Volume: 22, Issue:1

    Topics: 17-Hydroxycorticosteroids; Bipolar Disorder; Creatinine; Emotions; Factor Analysis, Statistical; Fem

1970
Plasma free fatty acids concentration in depressive illness.
    Archives of general psychiatry, 1970, Volume: 22, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Aged; Analysis of Variance; Anxiety; Behavior; Bipolar

1970
Dopamine excretion in affective states and following Li2Co3 therapy.
    Nature, 1970, Feb-28, Volume: 225, Issue:5235

    Topics: Adult; Bipolar Disorder; Carbonates; Dopamine; Fluorometry; Humans; Lithium; Middle Aged; Vanilmande

1970
Catecholamine metabolism in affective disorders. 3. MHPG and other catecholamine metabolites in patients treated with lithium carbonate.
    Journal of psychiatric research, 1970, Volume: 7, Issue:3

    Topics: Adrenal Medulla; Adult; Aged; Bipolar Disorder; Catecholamines; Catechols; Epinephrine; Female; Glyc

1970
Vanilmandelicaciduria in the different clinical phases of manic depressive psychosis.
    The British journal of psychiatry : the journal of mental science, 1970, Volume: 116, Issue:533

    Topics: Adult; Bipolar Disorder; Creatinine; Female; Humans; Mandelic Acids; Middle Aged; Vanilmandelic Acid

1970
Clinical and biochemical aspects of lithium therapy.
    Diseases of the nervous system, 1971, Volume: 32, Issue:2

    Topics: Affective Symptoms; Bipolar Disorder; Catecholamines; Dopamine; Humans; Lithium; Norepinephrine; Sch

1971
Catecholamine metabolism, depression and stress.
    Nature, 1971, Apr-02, Volume: 230, Issue:5292

    Topics: Bipolar Disorder; Brain Chemistry; Catecholamines; Depression; Female; Glycols; Humans; Male; Middle

1971
Catecholamine metabolism of manic-depressive illness.
    Journal of psychiatric research, 1968, Volume: 6, Issue:3

    Topics: Antidepressive Agents; Bipolar Disorder; Calcium; Catecholamines; Creatinine; Disulfiram; Dopamine;

1968
Vanilmandelic acid in urine and in cerebro-spinal fluid in different phases of manic-depressive psychosis.
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1968, Feb-28, Volume: 92, Issue:1

    Topics: Bipolar Disorder; Humans; Mandelic Acids; Vanilmandelic Acid

1968
The investigation of adrenergic metabolism with 7H3-norepinephrine in psychiatric disorders. I. Temporal changes in the distribution of urinary tritiated metabolites and the effects of drugs.
    Journal of psychiatric research, 1969, Volume: 6, Issue:4

    Topics: Amines; Bipolar Disorder; Chlorpromazine; Humans; Hydrogen-Ion Concentration; Injections, Intravenou

1969